Search results for " libraries"

Targeting HSP90 with the small molecule inhibitor AUY922 (luminespib) as a treatment strategy against hepatocellular carcinoma

2018

Hepatocellular carcinoma (HCC) is a highly malignant tumor that responds very poorly to existing therapies, most probably due to its extraordinary inter- and intra-tumor molecular heterogeneity. The modest therapeutic response to molecular targeted agents underlines the need for new therapeutic approaches for HCC. In our study, we took advantage of well-characterized human HCC cell lines, differing in transcriptomic subtypes, DNA mutation and amplification alterations, reflecting the heterogeneity of primary HCCs, to provide a preclinical evaluation of the specific heat shock protein 90 (HSP90) inhibitor AUY922 (luminespib). Indeed, HSP90 is highly expressed in different tumor types, but it…

Literacy Skills as Local Intangible Capital : The History of a Rural Lending Library c. 1860–1920

2016

Public Libraries – Facilitators of Information Society and e- Inclusion in Latvia

2014

Abstract The economic growth and national competitiveness is closely correlated with the development of information society. In the last few years the role of public libraries has significantly increased and libraries have greatly contributed to the improvement of information society in Latvia. The usage of library services had never been as high as they were in 2011 – 42% of the population were active library users and 90% of them used the Internet. Nowadays, the public library network in Latvia provides a powerful network of information, knowledge and community centres and they are highly demanded by society.

Public libraries, literary art activities and social inclusion

2019

This paper focuses on literary art activities in public libraries. The aim is to stimulate discussion on how literary art activities can promote socially sustainable development, a sense of community, and social inclusion. In Finland, public libraries organise low-threshold literary art activities that encourage both written and verbal expression, e.g. literary art clubs, rap and comics workshops, and creative writing groups. Literary art activities provide opportunities for the improvement of literacy, self-expression and social readiness, and the strengthening of self-esteem and identity. Moreover, they can promote community spirit. Libraries respond to current societal challenges and the…

Bibliotekāru iesaistīšanās darbā publiskajās viena darbinieka bibliotēkās

2021

Bibliotekāru iesaistīšanās darbā viena darbinieka bibliotēkās ir viens no bibliotēkas ikdienas procesu kvalitatīvas un efektīvas izpildes aspektiem. Apzinot personāla iesaistīšanās faktorus, ir iespējams noteikt un uzlabot bibliotekāru iesaistīšanos darbā. Pētījuma mērķis ir noskaidrot, vai viena darbinieka publiskajās bibliotēkās strādājošie bibliotekāri ir darbā iesaistījušies, un kādi faktori ietekmē to iesaistīšanos darbā. Pētījuma ievaros veikta viena darbinieka publisko bibliotēku bibliotekāru anketēšana un intervijas. Pētījuma rezultāti norāda, ka viena darbinieka publisko bibliotēku bibliotekāri ir darbā iesaistījušies vidēji divas dienas nedēļā, tomēr ir vairāki pastāvoši faktori, …

Highly occupied gauge theories in 2 + 1 dimensions : a self-similar attractor

2019

Motivated by the boost-invariant Glasma state in the initial stages in heavy-ion collisions, we perform classical-statistical simulations of SU(2) gauge theory in 2+1 dimensional space-time both with and without a scalar field in the adjoint representation. We show that irrespective of the details of the initial condition, the far-from-equilibrium evolution of these highly occupied systems approaches a unique universal attractor at high momenta that is the same for the gauge and scalar sectors. We extract the scaling exponents and the form of the distribution function close to this non-thermal fixed point. We find that the dynamics are governed by an energy cascade to higher momenta with sc…

Time-like Proton Form Factors with Initial State Radiation Technique

2022

Electromagnetic form factors are fundamental quantities describing the internal structure of hadrons. They can be measured with scattering processes in the space-like region and annihilation processes in the time-like region. The two regions are connected by crossing symmetry. The measurements of the proton electromagnetic form factors in the time-like region using the initial state radiation technique are reviewed. Recent experimental studies have shown that initial state radiation processes at high luminosity electron-positron colliders can be effectively used to probe the electromagnetic structure of hadrons. The BABAR experiment at the B-factory PEP-II in Stanford and the BESIII experim…

Formaldehyde and total aldehydes in indoor air of public environments by voltammetry

2014

The proposed method involves active sampling, where a sampling pump is used to pull air through a solution and voltammetric analysis of the obtained solutions. No interferences have been observed. In addition, very little sample preparation is required. Analyses were performed in 19 indoor stations and one in outdoor. Measurements were carried out on University environments: Museum of Chemistry, Zoological Museum, libraries, laboratories, corridors, meeting rooms, photocopying room, machine shop and terrace. Formaldehyde concentrations in analyzed samples ranged from 2.6 to 85 μg m-3 (median = 32 μg m-3), while the sum of others aldehydes ranged from 2 to 25 μg m-3 (median =2.4 μg m-3). In …

Iusti Lipsii De bibliothecis syntagma

Brief treatise that following a chronological order traces the history of ancient libraries, from the Egyptian ones to those of Imperial Rome.