Search results for " lichen"
showing 10 items of 170 documents
Oral lichen planus: a retrospective study of 633 patients from Bucharest, Romania
2012
Objective: In this retrospective study, patients’ medical records were reviewed to investigate the profiles of 633 OLP cases in a group of Romania. Material and Methods: In this retrospective study, the following clinical data were obtained from the medical charts of patients: gender, age, clinical presentation of OLP, site affected, presence of symptoms, extraoral manifestations of lichen planus, presence of systemic diseases, and history of medications. Results: Most (78.67%) OLP patients were female and the mean age at presentation was 52 years. The white type of the disease (reticular/papular/plaque lesions) was the main form encountered in this sample (48.97%). Among patients with avai…
Scoring systems for Oral Lichen Planus used by differently experienced raters
2017
BACKGROUND: Scoring systems have been widely used to evaluate the severity and activity of oral lichen planus (OLP). The aim of the present study was to compare two existing (one modified) scoring systems in the evaluation of OLP severity and correlation with pain. Three differently experienced raters were involved. MATERIALS AND METHODS: Consecutive patients with OLP were assessed for pain using the Visual Analogue Scale and examined at 10 intraoral sites before starting (T0) and three weeks after (T1) steroid therapy (Clobetasol). Three differently experienced raters evaluated photographs using two scoring systems designated White-Erosive-Atrophic (WEA) modified from an older WEA system (…
Topical treatment of oral lichen planus with anthocyanins
2014
Background: Oxidative stress is involved in oral lichen planus (OLP) pathogenesis; meanwhile anthocyanins are natural antioxidants present in grapes skin. Objectives: The aim of this research was to verify the utility of anthocyanins, extracted from grapes skin, for the local treatment of oral lichen planus and to compare it with clobetasol propionate- neomycin -nystatin cream (CP-NN). Study Design: Prospective, non-randomized study, with control group. Fifty-two patients with OLP were includ - ed. We divided patients into two categories: erosive oral lichen planus (EOLP) and non erosive oral lichen planus (NEOLP). 38 had EOLP (17 cases and 21 controls) and 14 presented NEOLP types (9 cases…
Thermal restraint of a bacterial exopolysaccharide of shallow vent origin
2018
This is the post-print version of the following article: "Thermal restraint of a bacterial exopolysaccharide of shallow vent origin", which has been published in final form at https://www.sciencedirect.com/science/article/pii/S0141813018308250?via%3Dihub; International audience; To dynamically characterize the thermal properties of the fructose-rich exopolysaccharide (EPS1-T14), produced by themarine thermophilic Bacillus licheniformis T14, the Attenuated Total Reflectance Fourier Transform Infra-Redspectroscopy was coupled to variable temperature ranging from ambient to 80 °C.The spectra were analyzed by the following innovative mathematical tools: i) non-ideal spectral deviation, ii) OHst…
Immune-Mediated Desquamative Gingivitis and Optical Coherence Tomography Diagnostic Patterns: Clinical Implication from a Systematic Review
2021
Desquamative Gingivitis (DG) comprises heterogeneous clinical manifestations of numerous immune-mediated muco-cutaneous diseases. Optical Coherence Tomography (OCT) has been proposed as a valuable diagnostic support even if, to date, there are no standardized OCT-diagnostic patterns applicable to DGs. A systematic review was performed to detect existing data on in vivo OCT diagnostic patterns of the most common immune-mediated DGs (i.e., pemphigus vulgaris, mucous membrane pemphigoid and oral lichen planus). It has been found that OCT exhibits specific patterns that address the diagnosis of DG by pemphigus vulgaris (i.e., intraepithelial unilocular blister, reduced epithelial thickness, pre…
Identification of Morphological Biosignatures in Martian Analogue Field Specimens Using In Situ Planetary Instrumentation
2008
International audience; We have investigated how morphological biosignatures (i.e., features related to life) might be identified with an array of viable instruments within the framework of robotic planetary surface operations at Mars. This is the first time such an integrated lab-based study has been conducted that incorporates space-qualified instrumentation designed for combined in situ imaging, analysis, and geotechnics ( sampling). Specimens were selected on the basis of feature morphology, scale, and analogy to Mars rocks. Two types of morphological criteria were considered: potential signatures of extinct life ( fossilized microbial filaments) and of extant life (crypto-chasmoendolit…
Eukaryotes Are a Holophyletic Group of Polyphyletic Origin.
2020
Because of the polyphyletic origin of the eukaryotic monophylum, eukaryogenesis within prokaryotes is not comparable with mammal origin within paraphyletic reptiles. Both synapomorphies and plesiomorphies represent apomorphies and are indeed suitable for defining monophyletic (holophyletic and paraphyletic) groups. Alphaproteobacteria (Bacteria) and Asgard (Archaea) are the ancestors of LECA (the Last Eukaryotic Common Ancestor). The presence of ESPs in Asgard does not dispute the polyphyletic origin of eukaryotes ; it only further corroborates it. “Candidatus Prometheoarchaeum syntrophicum” is the closest relative to eukaryotes and the only Asgard with available microscopy data. This newly…
The activity concentration of post-Chernobyl Cs in the area of the Opole Anomaly (southern Poland)
2015
During the years 2007 and 2010, the activity concentration of 137Cs accumulated in soil, mosses Pleurozium schreberi and lichens Hypogymnia physodes was measured. The studies covered the areas of the so-called Opole Anomaly. In consequence of the Chernobyl nuclear power plant breakdown in 1986, relatively large amounts of this radionuclide were deposited in this area. In some areas of the Anomaly, over 100 times higher surface activity of 137Cs was detected, compared to the lowest values registered in Poland. Currently, 137Cs is still present in woodlands and wastelands. As at 2 April 2013, the surface activity concentration of 137Cs in soil on the tested area was from 0.34 to 67.5 kBq m−2.…
Human papillomaviruses in oral carcinoma and oral potentially malignant disorders: a systematic review
2011
Oral Diseases (2011) 17 (Suppl. 1), 58–72 Objectives: Human papillomavirus (HPV) in oral carcinoma (OSCC) and potentially malignant disorders (OPMD) is controversial. The primary aim was to calculate pooled risk estimates for the association of HPV with OSCC and OPMD when compared with healthy oral mucosa as controls. We also examined the effects of sampling techniques on HPV detection rates. Methods: Systematic review was performed using PubMed (January 1966–September 2010) and EMBASE (January 1990–September 2010). Eligible studies included randomized controlled, cohort and cross-sectional studies. Pooled data were analysed by calculating odds ratios, using a random effects model. Risk o…
Angiogenesis of oral lichen planus: a possible pathogenetic mechanism.
2008
Objective: Oral Lichen Planus (OLP) is a chronic inflammatory disease with an autoimmune inflammatory pathogenesis. The aim of the research is to compare the vascular endothelial growth factor (VEGF) and adhesion of molecules in the biopsy samples of patients affected by OLP, in order to research the presence of the angiogenetic phenomenon and to understand its pathogenetic mechanism. Materials and Methods: Thirty OLP patients and thirty healthy subjects were enrolled in a study. The immunohistochemical analysis of the VEGF and vascularendothelial adhesion molecules was carried out by means of primary antibodies and anti-CD34, anti-VEGF, antiCD106 antigen (VCAM-1) and anti-CD54 antigen (ICA…