Search results for " life science"

Intérêt des oméga 3 pour la rétine

2015

La rétine en recherche appliquée

2015

Lipides et rétine - Aspects biologiques

2014

Dietary fatty acids in the retina: beyond DHA, is EPA the underestimate intermediate?

2016

Dietary fatty acids in the retina: beyond DHA, is EPA the underestimate intermediate?. 12. congress of the international society for the study of fatty acids and lipids

Cholesterol homeostasis and retinal stress in anterior ischemic optic neuropathy

2016

Purpose: Anterior ischemic optic neuropathy (AION) is characterized by acute stress of retinal ganglion cells (RGC). Cholesterol-24S-hydroxylase (CYP46A1) is specifically expressed in RGC where it may exert neuroprotective properties by preventing from cholesterol accumulation via catalyzing the formation of 24S-hydroxycholesterol. Previous findings hypothesize the housekeeping importance of CYP46A1 in the maintenance of cholesterol in the retina. In order to better understand the role of CYP46A1 in the retina, we aimed to define whether CYP46A1 expression and 24S-hydroxycholesterol levels were modified during RGC stress in AION.Methods: Ninety nine male Sprague Dawley rats were randomized …

Maintenance of anticoagulant and antiplatelet agents for patients undergoing vitreoretinal surgery

2009

International audience; Purpose: To establish the prevalence of anticoagulant, aspirin, and clopidogrel use in patients undergoing vitreoretinal surgery, and to compare the outcome of peribulbar anesthesia between users and non-users. Materials and Methods: We conducted a retrospective case series in one academic center between January and June 2009. We analyzed the chart of 239 eyes who underwent posterior segment surgery with peribulbar anesthesia. Data included age, reasons for anticoagulant and/or antiplatelet agents, operative procedure, history of diabetes mellitus, high blood pressure, axial globe length, pre and post operative visual acuity, complications rates during and after anes…

Severe corneal complications following vitreoretinal surgery

2011

Severe corneal complications following vitreoretinal surgery. annual meeting of the association-for-research-in-vision-and-ophthalmology (ARVO)

Regulation of immune response in post-operative endophthalmitis

2011

Regulation of immune response in post-operative endophthalmitis. annual meeting of the association-for-research-in-vision-and-ophthalmology (ARVO)

Problématiques de la nutrition en ophtalmologie – application à la dégénérescence maculaire liée à l’âge nutrition in ophthalmology – clinical applic…

2014

« Let food be your medicine. » This contribution from Hippocrates is still timely addressed, especially in the field of ophthalmology. Observational epidemiology reports close associations between food habits and the risk or prevention of several ocular pathologies such as cataract or Age-related Macular Degeneration (AMD). Anti-oxidant vitamins, minerals and lipids are the nutrients that have been the most widely studied. Interventional epidemiology and experimental works partially corroborated these findings. Unexpectedly, the benefit of long chain omega 3 polyunsaturated fatty acids in the prevention of late AMD was not firmly established in Age-Related Eye Disease Study 2 (AREDS2). Neve…

4812 - A0028 Gangliosides in the retina: a comparative inventory with brain and other ocular structures

2016

Purpose: Gangliosides (GG) make an extremely diverse family of glycosphingolipids particularly abundant in the brain and neural tissues. While it is known that alterations in GG metabolism are associated with visual defects, the precise biological roles of these compounds in the retina are still largely unknown. In this context, we performed an exhaustive inventory and thorough characterization of the human eye GG aiming to reveal specificities and common features of the retina compared to other ocular tissues and brain.Methods: Retina, RPE/Choroid, ciliary body, optic nerve and brain samples were collected from deceased human donors (N=7). GG were extracted and analysed by a comprehensive …