Search results for " longitudinal"
showing 10 items of 188 documents
Internuclear ophthalmoplegia of abduction: clinical and electrophysiological data on the existence of an abduction paresis of prenuclear origin.
1992
Three patients showed unilateral and five bilateral abduction paresis. Five had associated adduction nystagmus of the contralateral eye. Electrophysiological testing of masseter and blink reflexes indicated an ipsilateral rostral pontine or mesencephalic lesion, and excluded a lesion of the infranuclear portion of the abducens nerve. Abduction paresis was attributed to impaired inhibition of the tonic resting activity of the antagonistic medial rectus muscle. The prenuclear origin of the disorder is based on morphological and neurophysiological evidence of an ipsilateral inhibitory connection between the paramedian pontine reticular formation and the oculomotor nucleus running close to but …
Mathematical Model Predicts Clinical Ocular Motor Syndromes
2003
: Clinical ocular motor syndromes were compared with ocular motor syndromes simulated by a mathematical model of the vestibuloocular reflex. The mathematical sensorimotor feedforward model of otolith control of three-dimensional binocular eye position is based on relevant anatomical connections of the vestibuloocular reflex from the utricles to extraocular eye muscles. This is the first attempt to simulate static ocular motor syndromes for unilateral utricular or vestibular nerve failure, lesions of the vestibular nucleus, and lesions of the ascending vestibuloocular reflex pathways. Comparison of the predicted syndromes with those found in patients with unilateral disorders of the vestibul…
A national cohort study on pediatric Behçet's disease: Cross-sectional data from an Italian registry
2017
Abstract Background Behçet’s disease is a rare multi-systemic inflammatory disease with unknown etiology which involves principally oral and genital mucosa, skin and eyes. Average age at onset of the disease is about 25-30 years, but it may be diagnosed before the age of 16. It is not very rare in Italy, even though there are limited data concerning epidemiology. Aim of this study is to describe the baseline data of an Italian cohort of patients with as having BD or probable BD. Methods We described the baseline data of the first national epidemiological study on children coming from 16 Italian Pediatric Rheumatologic Centers diagnosed by the treating physicians as having Behçet’s Disease. …
Impact of insulin resistance on cardiac and vascular function.
2016
Background Insulin resistance (IR), constitutes an important cardiovascular risk factor and can cause ischemic heart disease. It can lead to left ventricular dysfunction with a mechanism independent of ischemic heart disease and it is closely associated with impaired vascular function. The aim of our study was to explore the impact of IR on cardiac and vascular function, in patients with cardiovascular risk factors but angiographically undamaged coronary arteries. Methods We studied 32 patients (62.06 ± 11.19 years) with cardiovascular risk factors. All patients underwent coronary angiography, echocardiography, Doppler ultrasound of carotid arteries and laboratory tests. Exclusion criteria …
Results of an Observational Cohort Study of Hyperuricemia as a Predictor of Poor Physical Performance in the Elderly
2017
Objective: Hyperuricemia is frequent in older people and associated with several medical conditions. The relationship between hyperuricemia and physical performance is limited. We aimed to investigate the association between hyperuricemia and physical performance over a 4.4-year followup in the elderly. Methods: A total of 1,904 community-dwelling older participants were followed for a mean of 4.4 years. Hyperuricemia at baseline was defined using serum uric acid concentrations ≥6 and ≥7 mg/dl for women and men, respectively. Objective physical performance tests measured included the Short Physical Performance Battery (SPPB), 4-meter gait speed, chair-stands time, leg extension and flexion,…
Correlation between longitudinal strain analysis and coronary microvascular dysfunction in patients with heart failure with preserved ejection fracti…
2020
Objective: The aim of this study was to evaluate in patients with microvascular angina and heart failure with preserved ejection fraction, the speckle-tracking echocardiography, and longitudinal myocardial strain to evaluate the possible presence of alterations in heart failure with preserved ejection fraction patients compared with a control population. We also investigated the correlation between the longitudinal strain analysis and the TIMI frame count after coronary angiography. Methods: Our study was performed on a population 41 patients with microvascular angina that underwent coronary angiography and speckle-tracking echocardiography. We divided the sample into two categories: patien…
Splenic marginal zone lymphoma: A prognostic model for clinical use
2006
The Integruppo Italiano Linfomi (IIL) carried out a study to assess the outcomes of splenic marginal zone lymphoma and to identify prognostic factors in 309 patients. The 5-year cause-specific survival (CSS) rate was 76%. In univariate analysis, the parameters predictive of shorter CSS were hemoglobin levels below 12 g/dL (P < .001), albumin levels below 3.5 g/dL (P = .001), International Prognostic Index (IPI) scores of 2 to 3 (P < .001), lactate dehydrogenase (LDH) levels above normal (P < .001), age older than 60 years (P = .01), platelet counts below 100 000/μL (P = .04), HbsAg-positivity (P = .01), and no splenectomy at diagnosis (P = .006). Values that maintained a negative influence …
Nature of water-biochar interface interactions
2012
A poplar biochar obtained by an industrial gasification process was saturated with water and analyzed using fast field cycling (FFC) NMR relaxometry in a temperature range between 299 and 353 K. Results revealed that the longitudinal relaxation rate increased with the increment of the temperature. This behavior was consistent with that already observed for paramagnetic inorganic porous media for which two different relaxation mechanisms can be accounted for: outer- and inner-sphere mechanisms. The former is due to water diffusing from the closest approach distance to infinity, whereas the second is due to water interacting by nonconventional H-bonds to the porous surface of the solid materi…
Internalizing problems as a mediator in the relationship between low effortful control and internet abuse in adolescence: A three-wave longitudinal s…
2019
Abstract The aim of the study is to examine the relationships between early adolescents' low effortful control, middle adolescents' internalizing problems and late adolescents' Internet abuse, focusing on the mediating role that middle adolescents' internalizing problems may play in the relationship between early adolescents' low effortful control and late adolescents' Internet abuse. The study followed a sample of 482 adolescents (245 boys and 237 girls) from early adolescence (wave 1; mean age = 14.76, SD = 0.63), through middle adolescence (wave 2; mean age = 15.77, SD = 0.61), to late adolescence (wave 3; mean age = 17.88, SD = 0.57). The participants completed self-report questionnaire…
Mobilités et changements de catégories : portée et limites des données longitudinales : XIXes journées d'étude sur les données longitudinales dans l'…
2012
De nombreuses recherches ont déjà démontré l'apport des données longitudinales pour déchiffrer le passage d'un état à un autre, et signaler des états transitoires, précaires ou durables, plus ou moins réversibles, plus ou moins ajustés aux attentes et aux dispositifs, en particulier entre formation et emploi. Des catégories ont été construites à l'appui de réflexions interdisciplinaires, telles que celles de transition, de cheminement long, de parcours, de carrières et bien d'autres. Dans un contexte sociétal où tout semble changer en même temps et où il est difficile de démêler les effets structurels et conjoncturels, ces avancées incitent aujourd'hui à attaquer de front la question comple…