Search results for " medicinal"
showing 10 items of 590 documents
Surface and volume non-invasive methods for the structural monitoring of the bass-relief ‘Madonna con Bambino’ (Gorizia, Northern Italy)
2016
Structural analysis of marble statues, carried out by non-invasive and in situ methods, is crucial to define the state of conservation of the artworks and to identify the deterioration phenomena that can affect them. In this work, we combined in situ non-destructive techniques, ultrasonic tomography (US), ultraviolet-induced visible fluorescence (UV-IF) and X-ray fluorescence (XRF) to study the bass-relief ‘Madonna con Bambino’ (Gorizia, Italy). The US revealed the presence of some metallic pivots, associated with areas of high sound velocity; moreover, a more degraded area has been identified in the lower part of the bass-relief. The acquired UV-IF image confirmed the presence of surface d…
Cytotoxicity and inhibition of P-glycoprotein by selected medicinal plants from Thailand.
2014
Abstract Ethnopharmacological relevance Thai medicine has a long tradition of tonifying medicinal plants. In the present investigation, we studied the flower extracts of Jasminum sambac, Mammea siamensis, Mesua ferrea, Michelia alba, Mimusops elengi, and Nelumbo nucifera and speculated that these plants might influence metabolism and substance flow in the body. Materials and methods Isolation of porcine brain capillary endothelial cells (PBCECs) as well as multidrug-resistance CEM/ADR5000 leukemia cells, MDA-M;B-231 breast cancer, U-251 brain tumor, and HCT-116 colon cancer cells were used. The calcein-acetoxymethylester (AM) assay was used to measure inhibition of P-glycoprotein transport.…
Induction of apoptosis in a leukemia cell line by triterpene saponins from Albizia adianthifolia
2004
Abstract Triterpenoid saponins, which are present in plants and some marine animals, exert various important pharmacological effects. The present study examines the effects of adianthifoliosides A, B, and D (AdA, AdB, and AdD) together with two prosapogenins (Pro1 and Pro2) obtained from Albizia adianthifolia (Mimosaceae) on human leukemia T-cells (Jurkat cells) and on splenocytes. AdA, AdB, and AdD were found to exhibit a cytotoxic effect on Jurkat cells, whereas the prosapogenins were found to exert a lymphoproliferative effect on this cell type. Furthermore, all tested compounds were found to exert a synergistic lymphoproliferative activity with concanavalin A (ConA) on splenocytes. The …
Fighting and non-fighting time-motion in taekwondo cadet athletes
2016
[Resumen] La relación entre los tiempos de lucha (L) y no lucha (NL) ha sido utilizada para caracterizar las demandas físicas del taekwondo. El objetivo del presente estudio es analizar el tiempo de L y NL en función de la categoría de competición en taekwondistas cadetes (12-14 años). Se analizaron las fases del tiempo de movimiento (L y NL) de 47 combates del primer Campeonato del Mundo Cadete en función de la categoría de competición (minimosca, mosca, gallo, pluma, ligero, superligero, semimedio, medio, semipesado y pesado). Se utilizó el test Kruskal-Wallis seguido de las pruebas por pares de U de Mann Whitney para analizar las diferencias entre grupos (p < 0,05). Se encontraron difere…
Sports activities in the natural environment: its representation in physical education textbooks in primary school
2017
El objeto de esta investigación es analizar las actividades deportivas realizadas en el medio natural representadas en los libros de texto de Educación Física (EF) en la etapa de Educación Primaria (EP), publicados en la Ley Orgánica 2/2006, de 3 de mayo, de Educación (LOE). Se analizan 4339 imágenes, recogidas en 44 libros de texto, pertenecientes a ocho editoriales españolas. Para el análisis de contenido de las imágenes se utilizó la herramienta SAIMEF (Sistema de Análisis de las Imágenes de Educación Física), elaborada ad hoc. La prueba piloto, el panel de expertos y la triangulación con varios observadores fueron algunos de los criterios de cientificidad que avalaron dicha herramienta.…
MuLiMs-MCoMPAs: A Novel Multiplatform Framework to Compute Tensor Algebra-Based Three-Dimensional Protein Descriptors
2019
This report introduces the MuLiMs-MCoMPAs software (acronym for Multi-Linear Maps based on N-Metric and Contact Matrices of 3D Protein and Amino-acid weightings), designed to compute tensor-based 3D protein structural descriptors by applying two- and three-linear algebraic forms. Moreover, these descriptors contemplate generalizing components such as novel 3D protein structural representations, (dis)similarity metrics, and multimetrics to extract geometrical related information between two and three amino acids, weighting schemes based on amino acid properties, matrix normalization procedures that consider simple-stochastic and mutual probability transformations, topological and geometrical…
Composition of essential oil of lemon thyme (Thymus × citriodorus) at different hydrodistillation times.
2018
Distillation time can both to optimise the production and to engineer the composition of essential oil in essential oil bearing plants. Purpose of this study was to evaluate the effect of duration of hydrodistillation on composition of essential oil of Thymus × citriodorus, the natural source of commercially important geraniol and citral, a component with valuable biological properties. Essential oils were isolated by hydrodistillation at different distillation times and analysed by GC/MS analytical methods. Increase in percentage of essential oil during all hydrodistillation time gradient was uneven. Elongation of hydrodistillation time decreased percentages of monoterpenes but increased p…
Preservation of vitamins content in Cuccìa using an innovative method of processing
2019
Cuccìa is a traditional Sicilian food prepared by boiling whole durum wheat kernels, in water, for many hours. This process destroys the vitamins E and B contents of crude kernels. It was rated a method to prepare the Cuccìa, preserving the vitamin content. Four varieties of durum wheat were processed comparing the traditional cooking method (TR-boiling for 5/6 hours), and an innovative one (IN-grains scarification, germination, and cooking at 50 °C for 2 hours). On soups obtained the content of biotin, niacin and α-amylase activity were determined. ANOVA showed the cooking method influences biotin and niacin content having values from 0.56 and 0.72 ng ml−1 (raw grain) and values close to 0…
Elucidating the aryl hydrocarbon receptor antagonism from a chemical-structural perspective.
2020
The aryl hydrocarbon receptor (AhR) plays an important role in several biological processes such as reproduction, immunity and homoeostasis. However, little is known on the chemical-structural and physicochemical features that influence the activity of AhR antagonistic modulators. In the present report, in vitro AhR antagonistic activity evaluations, based on a chemical-activated luciferase gene expression (AhR-CALUX) bioassay, and an extensive literature review were performed with the aim of constructing a structurally diverse database of contaminants and potentially toxic chemicals. Subsequently, QSAR models based on Linear Discriminant Analysis and Logistic Regression, as well as two tox…
Cytotoxic neo-clerodane diterpenes from Stachys aegyptiaca
2018
Abstract Two new E/Z neo-clerodane diterpene isomers, trivially named stachaegyptin D (1) and E (2), together with known compounds, stachysolon monoacetate (3) and stachysolon diacetate (4), were isolated from an organic-solvent extract of the medicinal herb Stachys aegyptiaca. Structures were elucidated by a combination of spectroscopic methods, including HREIMS, 1H, 13C, DEPT, and 2D NMR analysis, as well as, first time X-ray analysis for stachysolone (3). All isolated metabolites showed some activity against the human hepatocellular cell line, HepG2. Compound 4 was the most active with an IC50 of 59.5 μM.