Search results for " memory"
showing 10 items of 1351 documents
Rapid nucleus-scale reorganization of chromatin in neurons enables transcriptional adaptation for memory consolidation
2020
AbstractThe interphase nucleus is functionally organized in active and repressed territories defining the transcriptional status of the cell. However, it remains poorly understood how the nuclear architecture of neurons adapts in response to behaviorally relevant stimuli that trigger fast alterations in gene expression patterns. Imaging of fluorescently tagged nucleosomes revealed that pharmacological manipulation of neuronal activity in vitro and auditory cued fear conditioning in vivo induce nucleus-scale restructuring of chromatin within minutes. Furthermore, the acquisition of auditory fear memory is impaired after infusion of a drug into auditory cortex which blocks chromatin reorganiz…
RNA memory model: a RNA-mediated transcriptional activation mechanism involved in cell identity.
2010
Position-effect variegation (PEV) was discovered in Drosophila melanogaster in 1930 in a study of X-ray-induced chromosomal rearrangements. If a rearrangement places euchromatic genes adjacent to a region of centromeric heterochromatin, it gives a variegated phenotype that results from the random inactivation of genes by heterochromatin spreading from the breakpoint. After the establishment, the inactivation is henceforth clonally inherited. The vast majority of these modifiers were originally isolated in Drosophila as dominant mutations that suppressed or enhanced the variegation caused by a variegating white allele called white-mottled 4 (wm4). A large number of modifier genes alter PEV p…
New Characterization Methodology For Shape Memory Alloys
2011
Translating the Memory of the Holocaust: Thomas Geve’s Memoir
2020
espanolThis paper explores the most significant challenges of translating the memory of the Holocaust, focusing on the difficulties of transferring a survivor’s testimonial account to a different linguistic and cultural system. Because the concentration camp experience is inherently multicultural, and survivors have chosen to pen their ordeal in several languages, translation epitomizes a discipline that intertwines directly with the construction of universal collective memory. Consequently, translating Holocaust memoirs poses challenging questions on hermeneutics and deontology. Throughout the following pages, I will critically analyze my own Spanish rendition of Thomas Geve’s memoir, Guns…
Verbal and academic skills in children with early-onset type 1 diabetes
2010
Aim Basic verbal and academic skills can be adversely affected by early-onset diabetes, although these skills have been studied less than other cognitive functions. This study aimed to explore the mechanism of learning deficits in children with diabetes by assessing basic verbal and academic skills in children with early-onset diabetes and in comparison children. In addition, the incidence of dyslexia (≤10th centile in reading speed or reading–spelling accuracy) was studied. Method The performance of 51 children with early-onset diabetes (25 females, 26 males; mean age 9y 11mo, SD 4mo; range 9–10y) was compared with that of 92 children without diabetes (40 females, 52 males; mean age 9y 1…
Transitional Politics of Memory: Political Strategies of Managing the Past in Post-communist Romania
2017
The article develops a typology of political strategies of coming to terms with the past as a theoretical frame of reference against which it assesses the transitional politics of memory pursued in...
Testimony, updating and storytelling: the historical memory of Spanish Civil War in contemporary Catalan literature
2019
El tema de la Guerra Civil i la dictadura franquista ha generat a l’Estat espanyol des de mitjans dels noranta ençà una quantitat ingent de novel·les, articles periodístics, investigació històrica i producció audiovisual que palesa la vigència problemàtica del tema. Aquest article vol centrar-se en un aspecte d’aquesta producció: la referida a les narracions que dintre de la literatura catalana actual l’han abordat. Es tracta d’un corpus d’obres extens en el qual han participat alguns dels escriptors més destacats. La nostra aproximació pretén estudiar aquesta vasta i diversa producció, mirant d’esbrinar les motivacions i els plantejaments narratius que regeixen aquestes propostes. Hi hem d…
Historia del testimonio chileno : de las estrategias de denuncia a las políticas de memoria.
2008
Esta Historia del testimonio chileno describe críticamente la cambiante función que la palabra de los supervivientes de los campos de concentración chilenos ha desempeñado en la creación de imágenes y relatos de la violencia del régimen de Pinochet desde los meses posteriores al golpe hasta la actualidad. En los años que siguieron al golpe de 1973, los supervivientes unieron su voz a las múltiples plataformas de denuncia en el exilio que trataban de articular un amplio frente internacional contra la consolidación de la dictadura. Los testimonios de sus experiencias en los campos se vincularon a esa estrategia de resistencia, a la vez que permitían a los supervivientes dar sentido narrativo …
Computer Structure Laboratory
2019
La asignatura "Estructura de Computadores" es una asignatura obligatoria de segundo curso del Grado en Ingeniería Multimedia y del Grado en Ingeniería Informática. Tiene asignada una dedicación de 6 ECTS, siendo de carácter obligatorio en los dos grados. El material desarrollado son un total de 8 sesiones de laboratorio de 2 horas y media cada una, donde se estudia: jerarquía de memoria, centrándose en la memoria cache (3 sesiones), entrada y salida (2 sesiones) y periféricos (3 sesiones). En las 5 primeras prácticas se utiliza un software (MipsIt) que simula una máquina MIPS. En las 3 últimas sesiones se utiliza una máquina virtual con Linux. Las prácticas parten de ejemplos ya preparados …
Statistical Analysis of the (In)efficiency of Bitcoin : A comparison of the weak form efficient market hypothesis in the US and Venezuela
2019
Master's thesis Business Administration BE501 - University of Agder 2019 Bitcoin is a phenomenon that has received a lot of attentionduringthe last years. Although the literature on the subject has expanded, there is still need for more research. This paper replicates the work of Urquhart (2016) and examines whether there isevidence ofweak form efficiency in the Bitcoin market. He found that the Bitcoin market in the US showed signs of moving towards weak form efficiency. We contribute to the existing literature by adding recentdata and comparing two different markets;the USand Venezuela. To obtain robustness of the results, the analysis is conducted by performing six different statistical …