Search results for " metabolism"

Réseaux de distribution de l’énergie et sobriété énergétique des territoires, les apports d’une approche thermodynamique et métabolique des systèmes …

2017

Dans le contexte de transition énergétique et de crise environnementale actuel, les intérêts des approches territoriales et systémiques de l’énergie semblent aujourd’hui admis. Cependant et malgré les nombreuses avancées dans les domaines technologiques, en matière d’urbanisme et d’aménagement ou bien encore en termes d’approches psycho-sociales et comportementales, les courbes de consommations énergétiques peinent à s’infléchir. Fort de ce constat, nous posons l’hypothèse, sur la base d’éléments théoriques empruntés à la thermodynamique et à la biologie, du rôle potentiel que pourraient jouer les réseaux de distribution énergétique, leurs caractéristiques, leur morphologie et leur dynamiqu…

The impact of Nordic walking on bone properties in postmenopausal women with pre-diabetes and non-alcohol fatty liver disease

2021

This study investigated the impact of Nordic walking on bone properties in postmenopausal women with pre-diabetes and non-alcohol fatty liver disease (NAFLD). A total of 63 eligible women randomly participated in the Nordic walking training (AEx, n = 33), or maintained their daily lifestyle (Con, n = 30) during intervention. Bone mineral content (BMC) and density (BMD) of whole body (WB), total femur (TF), femoral neck (FN), and lumbar spine (L2-4) were assessed by dual-energy X-ray absorptiometry. Serum osteocalcin, pentosidine, receptor activator of nuclear factor kappa-B ligand (RANKL) levels were analyzed by ELISA assay. After an 8.6-month intervention, the AEx group maintained their BM…

Serum metabolic profiles in overweight and obese women with and without metabolic syndrome.

2014

Objective: To identify serum biomarkers through metabolomics approach that distinguishes physically inactive overweight/obese women with metabolic syndrome from those who are metabolically healthy, independent of body weight and fat mass. Methods: We applied nuclear magnetic resonance spectroscopy-based profiling of fasting serum samples to examine the metabolic differences between 78 previously physically inactive, body weight and fat mass matched overweight/obese premenopausal women with and without MetS. MetS was defined as the presence of at least three of the following five criteria: waist circumference ≥ 88 cm, serum triacylglycerol ≥ 1.7 mmol/L, and high density lipoprotein cholester…

Betatrophin Levels Are Related to the Early Histological Findings in Nonalcoholic Fatty Liver Disease

2021

Betatrophin, a liver hormone, regulates glucose and lipid metabolism. We investigated the betatrophin levels in nonalcoholic fatty liver disease (NAFLD) and searched for any relationship with histological severity and metabolic parameters. Fifty males with NAFLD [Nonalcoholic Steatohepatitis (NASH) (n = 32)

Estudios sobre la inmunogenicidad y los mecanismos fisiopatológicos de la proteína NSP4 de rotavirus.

2005

Rotavirus es el principal agente causante de gastroenteritis viral en niños y animales jóvenes en todo el mundo. Una de las principales proteínas de rotavirus es la glicoproteína no estructural 4 (NSP4) que juega un papel crucial tanto en el ciclo replicativo de rotavirus, actuando como receptor de partículas inmaduras en el retículo endoplasmático, como en la fisiopatología de rotavirus, siendo la primera enterotoxina de origen vírico descrita hasta el momento. El objetivo de la presente tesis fue clonar y producir la glicoproteína NSP4 de diferentes cepas humanas y animales de rotavirus para así poder realizar estudios inmunogénicos tales como la caracterización de epitopos presentes en l…

sport nutrition: from Lab to the field held

2018

Anthropometric Indicators as a Tool for Diagnosis of Obesity and Other Health Risk Factors: A Literature Review

2021

[EN] Obesity is characterized by the accumulation of an excessive amount of fat mass (FM) in the adipose tissue, subcutaneous, or inside certain organs. The risk does not lie so much in the amount of fat accumulated as in its distribution. Abdominal obesity (central or visceral) is an important risk factor for cardiovascular diseases, diabetes, and cancer, having an important role in the so-called metabolic syndrome. Therefore, it is necessary to prevent, detect, and appropriately treat obesity. The diagnosis is based on anthropometric indices that have been associated with adiposity and its distribution. Indices themselves, or a combination of some of them, conform to a big picture with di…

The Sick Adipose Tissue: New Insights Into Defective Signaling and Crosstalk With the Myocardium

2021

Adipose tissue (AT) biology is linked to cardiovascular health since obesity is associated with cardiovascular disease (CVD) and positively correlated with excessive visceral fat accumulation. AT signaling to myocardial cells through soluble factors known as adipokines, cardiokines, branched-chain amino acids and small molecules like microRNAs, undoubtedly influence myocardial cells and AT function via the endocrine-paracrine mechanisms of action. Unfortunately, abnormal total and visceral adiposity can alter this harmonious signaling network, resulting in tissue hypoxia and monocyte/macrophage adipose infiltration occurring alongside expanded intra-abdominal and epicardial fat depots seen …

Diet to Reduce the Metabolic Syndrome Associated with Menopause. The Logic for Olive Oil

2020

The rates of metabolic syndrome are increasing in parallel with the increasing prevalence of obesity, primarily due to its concomitant insulin resistance. This is particularly concerning for women, as the years around menopause are accompanied by an increase in visceral obesity, a strong determinant of insulin resistance. A fall in estrogens and increase in the androgen/estrogen ratio is attributed a determining role in this process, which has been confirmed in other physiological models, such as polycystic ovary syndrome. A healthy lifestyle, with special emphasis on nutrition, has been recommended as a first-line strategy in consensuses and guidelines. A consistent body of evidence has ac…

Taste of Fat and Obesity: Different Hypotheses and Our Point of View

2022

Obesity results from a temporary or prolonged positive energy balance due to an alteration in the homeostatic feedback of energy balance. Food, with its discriminative and hedonic qualities, is a key element of reward-based energy intake. An alteration in the brain reward system for highly palatable energy-rich foods, comprised of fat and carbohydrates, could be one of the main factors involved in the development of obesity by increasing the attractiveness and consumption of fat-rich foods. This would induce, in turn, a decrease in the taste of fat. A better understanding of the altered reward system in obesity may open the door to a new era for the diagnosis, management and treatment of th…