Search results for " modifica"

Covalently modified halloysite clay nanotubes: synthesis, properties, biological and medical applications

2017

Halloysite (HNT) is a promising natural nanosized tubular clay mineral that has many important uses in different industrial fields. It is naturally occurring, biocompatible, and available in thousands of tons at low cost. As a consequence of a hollow cavity, HNT is mainly used as nanocontainer for the controlled release of several chemicals. Chemical modification of both surfaces (inner lumen and outer surface) is a strategy to tune the nanotube's properties. Specifically, chemical modification of HNT surfaces generates a nanoarchitecture with targeted affinity through outer surface functionalization and drug transport ability from functionalization of the nanotube lumen. The primary focus …

A NEW ROUTE TO OBTAIN PANI-EAA FLEXIBLE FILMS

2010

Tarkkaavaisuushäiriöiden helpottaminen koulun keinoin : neljä esimerkkiä behavioraalisen intervention toteuttamisesta

2002

Ileostomía virtual como alternativa al estoma de protección en el cáncer de ovario avanzado. Ileostomía sistemática o selectiva. Papel de la endoscop…

2020

Entre todos los cánceres del tracto genital femenino, el cáncer de ovario es el segundo en orden de frecuencia y el de mayor mortalidad. En España se diagnostican unos 3.300 casos nuevos anuales, lo que representa el 5% de los canceres entre las mujeres. La incidencia en nuestro país es de aproximadamente 9 nuevos casos / 100.000 habitantes/año. La tasa de mortalidad es de 4 muertes /100.000 habitantes/año. En el momento del diagnóstico, el 75% de las pacientes están en un estadio avanzado de la enfermedad (III o IV). Las cifras de supervivencia disminuyen drásticamente entre los estadio I al IV. La exenteración pélvica posterior modificada es un procedimiento que se realiza con frecuencia …

Ni@Fe2O3 heterodimers: controlled synthesis and magnetically recyclable catalytic application for dehalogenation reactions

2012

Ni@Fe2O3 heterodimer nanoparticles (NPs) were synthesized by thermal decomposition of organometallic reactants. After functionalization, these Ni@Fe2O3 heterodimers became water soluble. The pristine heterodimeric NPs were characterized by transmission electron microscopy (TEM), X-ray diffraction (XRD), Mossbauer spectroscopy and magnetic susceptibility measurements. A special advantage of the heterodimers lies in the fact that nanodomains of different composition can be used as catalysts for the removal of environmentally hazardous halogenated pollutants.

Synthesis and preliminary in vivo evaluation of well-dispersed biomimetic nanocrystalline apatites labeled with positron emission tomographic imaging…

2015

In recent years, biomimetic synthetic apatite nanoparticles (AP-NPs), having chemical similarity with the mineral phase of bone, have attracted a great interest in nanomedicine as potential drug carriers. To evaluate the therapeutic perspectives of AP-NPs through the mechanisms of action and organs they interact with, the noninvasive monitoring of their in vivo behavior is of paramount importance. To this aim, here the feasibility to radiolabel AP-NPs ("naked" and surface-modified with citrate to reduce their aggregation) with two positron emission tomographic (PET) imaging agents ([F-18]NaF and Ga-68-NO(2)AP(BP)) was investigated. [F-18]NaF was used for the direct incorporation of the radi…

Synthesis and Characterisation of Functionalized borosilicate nanoparticles for boron neutron capture therapy applications

2012

Boron Neutron Capture Therapy (BNCT) is a promising therapy for the cure of diffuse tumors. The successful clinical application of BNCT requires finding new boron-based compounds suitable for an efficient 10B delivery to the cancerous tissues. The purpose of this work is to synthesize borosilicate nanoparticles by a sol–gel recipe, and to functionalize them with folic acid in order to promote their capture by the tumor cells. Whereas sol–gel is a promising technique for the synthesis of nanoparticles, in case of borosilicate systems this approach is affected by significant boron loss during preparation. Here we show that functionalization of borosilicate nanoparticles with folic acid can re…

Fluorination of some highly functionalized cycloalkanes: chemoselectivity and substrate dependence.

2017

A study exploring the chemical behavior of some dihydroxylated β-amino ester stereo- and regioisomers, derived from unsaturated cyclic β-amino acids is described. The nucleophilic fluorinations involving hydroxy–fluorine exchange of some highly functionalized alicyclic diol derivatives have been carried out in view of selective fluorination, investigating substrate dependence, neighboring group assistance and chemodifferentiation.

Jet shape modification in Pb-Pb collisions at √S[sub]N[sub]N= 2.76 TeV using two-particle correlations

2018

This thesis focuses on two separate topics. The first topic concerns the upgrade of the Time Projection Chamber (TPC) detector of the ALICE experiment. The upgrade will take place during the second Long Shutdown (2019-2020). The part of the upgrade I participated in was the replacement of the detector’s current readout electronics with Gas Electron Multiplier (GEM) foils. This change would allow for the continuous readout of the data, resulting in a hundredfold increase in the amount of data the ALICE experiment can process, as the TPC is the central tracking detector. I was involved in the Quality Assurance (QA) of these GEM foils. The advanced QA procedure consists of three measurements, a…

Deterministic Modification of CVD Grown Monolayer MoS2 with Optical Pulses

2021

| openaire: EC/H2020/820423/EU//S2QUIP | openaire: EC/H2020/834742/EU//ATOP Transition metal dichalcogenide monolayers have demonstrated a number of exquisite optical and electrical properties. Here, the authors report the optical modification of topographical and optical properties of monolayer MoS2 with femtosecond pulses under an inert atmosphere. A formation of three-dimensional structures on monolayer MoS2 with tunable height up to ≈20 nm is demonstrated. In contrast to unmodified monolayer MoS2, these optically modified structures show significantly different optical properties, such as lower photoluminescence intensity and longer fluorescence lifetime. The results suggest a novel way…