Fluorination of some highly functionalized cycloalkanes: chemoselectivity and substrate dependence.

6533b826fe1ef96bd1283d71

RESEARCH PRODUCT

Fluorination of some highly functionalized cycloalkanes: chemoselectivity and substrate dependence.

Loránd Kiss Santos Fustero Attila Márió Remete Melinda Nonn Matti Haukka Ferenc Fülöp

subject

isomeria Diol chemistry.chemical_element aminohapot 010402 general chemistry 01 natural sciences Full Research Paper lcsh:QD241-441 chemistry.chemical_compound Alicyclic compound Nucleophile lcsh:Organic chemistry fluorine Structural isomer Organic chemistry stereoisomers Chemoselectivity lcsh:Science ta116 chemistry.chemical_classification amino acids 010405 organic chemistry Organic Chemistry Substrate (chemistry)03.01. Általános orvostudomány fluori 0104 chemical sciences Chemistry chemistry chemoselectivity Fluorine Surface modification functionalization lcsh:Q

description

A study exploring the chemical behavior of some dihydroxylated β-amino ester stereo- and regioisomers, derived from unsaturated cyclic β-amino acids is described. The nucleophilic fluorinations involving hydroxy–fluorine exchange of some highly functionalized alicyclic diol derivatives have been carried out in view of selective fluorination, investigating substrate dependence, neighboring group assistance and chemodifferentiation.

year	journal	country	edition	language
2017-01-01	Beilstein journal of organic chemistry

10.3762/bjoc.13.233 https://pubmed.ncbi.nlm.nih.gov/29181116

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