Search results for " molecule"

showing 10 items of 1523 documents

Computational investigations of 18-electron triatomic sulfur–nitrogen anions

2018

MRCI-SD/def2-QZVP and PBE0/def2-QZVP calculations have been employed for the analysis of geometries, stabilities, and bonding of isomers of the 18-electron anions N2S2−, NS2−, and NSO−. Isomers of the isoelectronic neutral molecules SO2, S2O, S3, and O3 are included for comparison. The sulfur-centered acyclic NSN2−, NSS−, and NSO− anions are the most stable isomers of their respective molecular compositions. However, the nitrogen-centered isomers SNS− and SNO− lie close enough in energy to their more stable counterparts to allow their occurrence. The experimental structural information, where available, is in good agreement with the optimized bond parameters. The bonding in all investigate…

anionit010405 organic chemistryisomeriaTriatomic moleculeOrganic Chemistrychemistry.chemical_elementGeneral ChemistryElectron010402 general chemistrylaskennallinen kemia01 natural sciencesSulfurNitrogenCatalysis0104 chemical scienceselectronic structureschemistry18-electron triatomicssulfur–nitrogen anionsrikkiyhdisteetPhysical chemistryisomerstyppiyhdisteettheoretical calculations
researchProduct

Anti-oxidant and anti-inflammatory properties of betalains from Cactus Pear

2004

Anti-oxidant and anti-inflammatory properties of Betalains from Cactus Pear. C. Gentile1, A. Marconi1, M. A. Livrea2, G. Uzan1, P. D’Alessio1. 1 Inserm U602, Paris, France. 2 Dip. Farmacochimico, Tossicologico e Biologico, Università Palermo, Italy. Betalains of phytochemical origin, known as potent radical-scavengers in chemical and biological systems, have been tested in a model of inflammation. New phytochemicals are continuously inspected for potential pharmacological applications. The red betanin and the yellow indicaxanthin have recently been isolated and characterized from Cactus Pear. Reactive Oxygen Species may be toxic or display a regulatory character. During the inflammation rea…

betalains endothelial cells inflammation adhesion molecules
researchProduct

Bioactive molecules from soil and marine bacteria: new potential applications

2015

bioactive moleculeSettore BIO/11 - Biologia Molecolarebioactive molecules; soil; sea urchinsoilsea urchin
researchProduct

Biological activities of the extracts from macroalgae Carpodesmia crinita, Carpodesmia brachycarpa, Asparagopsis taxiformis

2023

Marine species represent a rich source of biologically active products that can be used in various fields. Among them, marine algae produce numerous secondary metabolites responsible for different biological activities such as: immunomodulatory [1], antioxidant [2], and antimicrobial [3]. The aim of this study was chemically characterizing the extracts of three macroalgae species: Carpodesmia crinite (Duby) Orellana & Sansón, 2019, Carpodesmia brachycarpa (J. Agardh) Orellana & Sansón 2019, Asparagopsis taxiformis (Delile) Trevisan 1845 and evaluate their biological activities. The characterization of the secondary metabolites was performed by HPLC-MS and the results obtained showed…

bioactive moleculemacroalgaeantimicrobial activitySettore BIO/10 - BiochimicainvertebrateSettore BIO/05 - ZoologiaSettore CHIM/06 - Chimica OrganicaSettore BIO/06 - Anatomia Comparata E Citologiasea urchinSettore AGR/16 - Microbiologia Agraria
researchProduct

ANTIMICROBIAL ACTIVITY FROM POLYPEPTIDE-RICH EXTRACTS OF THE SEAGRASS POSIDONIA OCEANICA

2021

The present study was carried out to assess the antibacterial, antifungal and antibiofilm properties of polypeptide-rich extracts isolated from green leaves and rhizomes of Mediterranean seagrass Posidonia oceanica (L. Delile) (Posidoniaceae). The seagrass was collected, washed with freshwater, grinded with liquid nitrogen in order to obtain fine powders that were exposed to extraction by acetic acid and antiproteases. The crude extracts isolated from leaves and rhizomes of P. oceanica were subjected to microbiological assays to evaluate the antibacterial, antifungal and antibiofilm activity of polypeptide fraction against two reference bacterial strains Staphylococcus aureus ATCC 25923 and…

bioactive moleculemarine biodiversityseagraantimicrobial activityantifungal activity
researchProduct

Biotecnology and Cultural Heritage: bioactive molecules applied in restoration projects

2014

bioactive molecules
researchProduct

Harnessing nature's insights: synthetic small molecules with peroxidase-mimicking DNAzyme properties.

2011

International audience

biology010405 organic chemistryOrganic ChemistryDeoxyribozymeNanotechnologyGeneral Chemistry[CHIM.CATA]Chemical Sciences/CatalysisDNA Catalytic010402 general chemistry01 natural sciencesSmall moleculeCatalysis0104 chemical scienceschemistry.chemical_compoundHeterocyclic Compounds 1-RingchemistryPeroxidasesBiomimetic MaterialsBiomimeticsbiology.proteinBioorganic chemistryHeminComputingMilieux_MISCELLANEOUSHeminPeroxidaseChemistry (Weinheim an der Bergstrasse, Germany)
researchProduct

Antimykotische Wirkstoffe, Mitt. Chlor-(1-piperazinyl)-1,3,5-triazine

1988

Aus der Umsetzung von Cyanurchlorid (1) mit den Piperazinderivaten 2a–c bei –20 bis 10° gehen die Dichlor-(1-piperazinyl)-1,3,5-triazine 3a–c hervor. Bei der erhohten Reaktionstemperatur von 40° erfolgt aus 1 und den Piperazinderivaten 4a–b Bildung der 2-Chlor-4,6-bis(piperazinyl)-1,3,5-triazine 5a–b. Zu gemischt substituierten Chlor-1,3,5-triazinen 9 fuhrt die nacheinander erfolgende Umsetzung von 1 mit 2 verschiedenen cyclischen sekundaren Aminen (6 und 8). Die Strukturtypen 3, 5 und 9 zeigen in den 1H-NMR-Spektren zwei fur Piperazinringe charakteristische Signalgruppen im Bereich 2.4–4.0 ppm. Unter den neu entwickelten Verbindungen finden sich Vertreter mit sehr starker antimykotischer W…

biologyBicyclic moleculeStereochemistryCyanuric chloridePharmaceutical ScienceTrichophyton rubrumbiology.organism_classificationPiperazinechemistry.chemical_compoundReaction temperaturechemistryDrug DiscoveryMicrosporum canisMicrosporumArchiv der Pharmazie
researchProduct

New umbelliferone sesquiterpene ethers from roots ofLigularia persica

1991

An extract of roots of Ligularia persica yielded thirteen umbelliferone sesquiterpene ethers, among them the new ones ligupersin A (11) and ligupersin B (13).

biologyBicyclic moleculeStereochemistryLigulariaOrganic ChemistryEtherNuclear magnetic resonance spectroscopySesquiterpenebiology.organism_classificationUmbelliferoneCoumarinchemistry.chemical_compoundchemistryOrganic chemistryPhysical and Theoretical ChemistryLiebigs Annalen der Chemie
researchProduct

Natural Products as Inhibitors of Epidermal Growth Factor Receptor

2011

biologyCancerTraditional Chinese medicinePharmacognosyPharmacologymedicine.diseaseBiochemistrySmall moleculeGeneticsbiology.proteinmedicineMolecular MedicineEpidermal growth factor receptorTyrosine kinaseBiotechnologyForum on Immunopathological Diseases and Therapeutics
researchProduct