Search results for " multiple"
showing 10 items of 903 documents
Combined approach for the investigation of dominant fermenting microbiota in two traditional sourdoughs produced in sicily
2017
In order to explore the community of lactic acid bacteria (LAB) and yeasts present in two major typical Sicilian sourdoughs, seven mature sourdoughs for "Pane Nero di Castelvetrano" (CV1 - CV3 samples) and "Pane di Monreale" (MR1 - MR4 samples) were analysed through a culturedependent and culture-independent approach. The highest values of microbial counts were revealed in MR1 sourdough. In particular, LAB counts were at about 109 CFU/g in media specific for typical sourdough LAB, such as SDB and SFM, while levels of 106 CFU/g were registered for yeasts. The total DNA form each sourdough sample was extracted and subjected to a multiplex-PCR in order to recognize the major groups of LAB. Sev…
A performance study of LTE MIMO-OFDM systems using the extended one-ring MIMO channel model
2012
In this paper, we consider a long-term evolution (LTE) system for the downlink by using multiple-input multiple-output (MIMO) orthogonal frequency division multiplexing (OFDM) techniques. The downlink channel is modeled by the socalled extended MIMO one-ring model. This model extends the well-known narrowband one-ring model with respect to frequency selectivity. The symbol error rate (SER) performance of the LTE MIMO-OFDM system is investigated for the downlink by employing different kinds of spatial encoders, where it is assumed that the channel state information (CSI) is perfectly known. For comparison, the space-time block coding (STBC) scheme, the vertical Bell Laboratories layered spac…
Filter multiplexing by use of spatial Code Division Multiple Access approach.
2003
The increasing popularity of optical communication has also brought a demand for a broader bandwidth. The trend, naturally, was to implement methods from traditional electronic communication. One of the most effective traditional methods is Code Division Multiple Access. In this research, we suggest the use of this approach for spatial coding applied to images. The approach is to multiplex several filters into one plane while keeping their mutual orthogonality. It is shown that if the filters are limited by their bandwidth, the output of all the filters can be sampled in the original image resolution and fully recovered through an all-optical setup. The theoretical analysis of such a setup …
Signal detection for spread spectrum communication systems with gradient algorithm
2012
Retrieval process of original symbols of a spread spectrum based communication system is tried to be improved by Gradient Algorithm (GA) and Blind Source Separation (BSS) principles. Two simple schemes, based on two energy functions are presented. Time correlation properties of the channel are used as advantages in developing the filter coefficients for the receiver. Direct Sequence - Code Division Multiple Access (DS-CDMA) technique based system setup is used for algorithm testing purposes. This is identified as one of the most stable spread spectrum communication technique where most of the technologies developed for that are highly compatible with High Speed Packet Access (HSPA) transmis…
Evaluating currency crises: the case of the European monetary system
2007
In this paper we examine the nature of currency crises. We ascertain whether the currency crises of the European Monetary System (EMS) were based either on fundamentals, or on self-fulfilling market expectations driven by extrinsic uncertainty. In particular, we extend previous work of Jeanne and Masson (J Int Econ 50:327–350, 2000) regarding the evaluation of currency crisis. We contribute to the existing literature proposing the use of Markov regime-switching with time-varying transition probability model. Our empirical results suggest that the currency crises of the EMS were not due only to market expectations driven by external uncertainty, or ‘sunspots’, but also to fundamental variabl…
Synthesis and study of cytotoxic activity of 1,2,4-trioxane- and egonol-derived hybrid molecules against Plasmodium falciparum and multidrug-resistan…
2014
Abstract Malaria and cancer cause the death of millions of people every year. To combat these two diseases, it is important that new pharmaceutically active compounds have the ability to overcome multidrug resistance in cancer and Plasmodium falciparum strains. In search of effective anti-cancer and anti-malaria hybrids that possess improved properties compared to their parent compounds, a series of novel 1,2,4-trioxane-based hybrids incorporating egonol and/or ferrocene fragments were synthesized and tested in vitro against P. falciparum strains, CCRF–CEM cells and the multidrug-resistant P-glycoprotein-over-expressing CEM/ADR5000 cells. The most active compounds against P. falciparum stra…
Furoquinolines and dihydrooxazole alkaloids with cytotoxic activity from the stem bark of Araliopsis soyauxii.
2018
Abstract Two new furoquinoline alkaloids, maculine B (1) and kokusaginine B (2) and one new dihydrooxazole alkaloid, veprisazole (3), along with four known compounds namely, N13-methyl-3-methoxyrutaecarpine (4), flindersiamine (5), skimmianine (6) and tilianin (7) were isolated from the methanol extract of the stem bark of Araliopsis soyauxii Engl. by various chromatographic methods. Their structures were determined using spectrometry and spectroscopic techniques including NMR and MS. The cytotoxicity of the new compounds compared to that of doxorubicin, the reference anticancer compound, was determined on a panel of nine cancer cell lines including sensitive and drug resistant phenotypes. …
Interplay of three G‑quadruplex units in the KIT promoter
2019
The proto-oncogene KIT encodes for a tyrosine kinase receptor, which is a clinically validated target for treating gastrointestinal stromal tumors. The KIT promoter contains a G-rich domain within a relatively long sequence potentially able to form three adjacent G-quadruplex (G4) units, namely, K2, SP, and K1. These G4 domains have been studied mainly as single quadruplex units derived from short truncated sequences and are currently considered promising targets for anticancer drugs, alternatively to the encoded protein. Nevertheless, the information reported so far does not contemplate the interplay between those neighboring G4s in the context of the whole promoter, possibly thwarting dru…
Intrahepatic cholangiocarcinoma: Limitations for resectability, current surgical concepts and future perspectives.
2020
Intrahepatic cholangiocarcinoma (iCCA) is the second most common hepatic malignancy and its incidence has been shown to increase significantly during the past decades. Complete surgical resection is currently acknowledged as the only curative treatment option able to provide adequate long-term outcomes. We herein review technical, functional and oncologic limitations for resectability, discuss current surgical aspects as well as highlight the fields in which future research and practice should focus on in order to ameliorate long-term outcomes in patients with iCCA.
Sustainable Renovation Framework: Introducing three levels of Integrated Design Process Implementation and Evaluation
2017
Future sustainable building renovation is a balance between the economic and environmental impacts related to the desired social activities facilitated by the renovated building. A review of recent research has revealed that the present efforts on sustainable objectives fulfilment in renovation projects are not sufficient. This paper investigates processes and frameworks in building renovation. It aims to deal with simplification of the existing complexity due to involvement of various types of stakeholders, sustainability criteria and potential renovation technologies in design process. Moreover, it facilitates understanding of the design process implementation through identification of th…