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RESEARCH PRODUCT
Intrahepatic cholangiocarcinoma: Limitations for resectability, current surgical concepts and future perspectives.
Nikolaos MachairasGeorgios C. SotiropoulosDimitri A. RaptisKumar JayantHauke Langsubject
Surgical resectionmedicine.medical_specialty030230 surgeryResectionBile duct cancerCholangiocarcinomaNeoplasms Multiple Primary03 medical and health sciences0302 clinical medicinePostoperative ComplicationsmedicineHepatectomyHepatic InsufficiencyHumansIn patientNeoplasm InvasivenessIntensive care medicineIntrahepatic Cholangiocarcinomabusiness.industryMargins of ExcisionGeneral Medicinemedicine.diseaseHepatic malignancyNeoadjuvant TherapyLiver TransplantationBile Ducts IntrahepaticOncologyBile Duct NeoplasmsCurative treatment030220 oncology & carcinogenesisBlood VesselsLymph Node ExcisionSurgeryLaparoscopyNeoplasm Recurrence Localbusinessdescription
Intrahepatic cholangiocarcinoma (iCCA) is the second most common hepatic malignancy and its incidence has been shown to increase significantly during the past decades. Complete surgical resection is currently acknowledged as the only curative treatment option able to provide adequate long-term outcomes. We herein review technical, functional and oncologic limitations for resectability, discuss current surgical aspects as well as highlight the fields in which future research and practice should focus on in order to ameliorate long-term outcomes in patients with iCCA.
year | journal | country | edition | language |
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2020-05-01 | European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology |