Search results for " mutagenesis"

showing 10 items of 2215 documents

Academic competence, teacher–student relationship, and violence and victimisation in adolescents: The classroom climate as a mediator

2021

School violence is a serious social and public health problem prevalent worldwide. Although the relevance of teacher and classroom factors is well established in the literature, few studies have focused on the role of teacher perceptions in school violence and victimisation and the potential mediational role of classroom climate in this relationship. A total of 2399 adolescents (50% girls), aged between 11 and 18 years (M = 14.65, SD = 1.78) and enrolled in five Spanish Secondary Compulsory Education schools completed measures of classroom climate, school violence towards peers and perception of peer victimisation, and their teachers informed about their academic competence and the teacher&…

medicine.medical_specialtyMediation (statistics)AdolescentHealth Toxicology and Mutagenesismedia_common.quotation_subjectViolència escolarProtective factorlcsh:Medicineacademic competence050109 social psychologyViolenceCompulsory educationVictimisationteacher–student relationshipArticleStructural equation modelingDevelopmental psychologyclassroom climatePerceptionmedicineHumansmediation0501 psychology and cognitive sciencesadolescentsChildStudentsCrime Victimsmedia_commonClassroom climateschool violenceSchoolsPublic healthlcsh:R05 social sciencesPublic Health Environmental and Occupational HealthBullyingschool victimisationFemaleViolència juvenilPsychology050104 developmental & child psychology
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Statistical Advances in Epidemiology and Public Health

2021

The key role of statistical modeling in epidemiology and public health is unquestionable [...]

medicine.medical_specialtyModels StatisticalManagement scienceHealth Toxicology and MutagenesisPublic healthlcsh:RPublic Health Environmental and Occupational HealthMEDLINElcsh:MedicineStatistical modelStatisticalEditorialn/aEpidemiologyKey (cryptography)medicinePublic HealthSociologyPublic Health.Introductory Journal ArticleModelInternational Journal of Environmental Research and Public Health
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A Multivariate Age-Structured Stochastic Model with Immunization Strategies to Describe Bronchiolitis Dynamics

2021

Bronchiolitis has a high morbidity in children under 2 years old. Respiratory syncytial virus (RSV) is the most common pathogen causing the disease. At present, there is only a costly humanized monoclonal RSV-specific antibody to prevent RSV. However, different immunization strategies are being developed. Hence, evaluation and comparison of their impact is important for policymakers. The analysis of the disease with a Bayesian stochastic compartmental model provided an improved and more natural description of its dynamics. However, the consideration of different age groups is still needed, since disease transmission greatly varies with age. In this work, we propose a multivariate age-struct…

medicine.medical_specialtyMultivariate statisticsStochastic modellingstochastic Bayesian modelHealth Toxicology and Mutagenesisrespiratory syncytial virusBayesian probabilityDiseaseRespiratory Syncytial Virus InfectionsPoisson distributioninfectious diseasesArticle03 medical and health sciencessymbols.namesakemultivariate age-structured model0302 clinical medicine030225 pediatricsMedicineHumans030212 general & internal medicineIntensive care medicineChildAge structuredimmunization programsbusiness.industryPublic Health Environmental and Occupational HealthInfant NewbornRInfantBayes TheoremImmunization (finance)medicine.diseaseRespiratory Syncytial VirusesBronchiolitisChild PreschoolsymbolsMedicineImmunizationbronchiolitisbusinessInternational Journal of Environmental Research and Public Health
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The Management of Health Hazards Related to Municipal Solid Waste on Fire in Europe: An Environmental Justice Issue?

2020

Landfilling should be the last option in an integrated Municipal Solid Waste (MSW) management approach. In the European Union (EU), the policy framework to protect the environment and the public health against the impact of health hazards related to urban solid waste management has been consistently implemented in recent decades. A growing interest in the negative impact of fires in waste landfills on the environment and people’s health was reported in some European countries. In Italy, an increasing occurrence of arsons in MSW and landfills has been reported in recent years. During the summer of 2012, a multi-site arson occurred in the Palermo Municipal solid waste landfill of Bellolampo (…

medicine.medical_specialtyMunicipal solid wasteHealth Toxicology and Mutagenesislcsh:MedicineCase ReportEnvironment pollution010501 environmental sciencesSettore MED/42 - Igiene Generale E Applicata01 natural sciences03 medical and health sciences0302 clinical medicinehealth effectsMultidisciplinary approachmedicinemedia_common.cataloged_instance030212 general & internal medicineEuropean unionEnvironmental justiceEnvironmental planning0105 earth and related environmental sciencesmedia_commonEnvironmental justicePublic healthPublic healthlcsh:RPublic Health Environmental and Occupational HealthMunicipal solid wasteArsonHealth effectProduct (business)Health effectBusinessInternational Journal of Environmental Research and Public Health
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Impact of Palliative Care in Evaluating and Relieving Symptoms in Patients with Advanced Cancer. Results from the DEMETRA Study

2020

Background: Cancer patients experience multiple symptoms throughout the course of the disease. We aimed to provide a comprehensive analysis of the symptom burden in patients with advanced cancer at admission to specialist palliative care (PC) services and seven days later to estimate the immediate impact of PC intervention. Patient and methods: The analysis was based on an observational, prospective, multicenter study (named DEMETRA) conducted in Italy on new patients accessing network specialist PC centers during the period May 2017&ndash

medicine.medical_specialtyPalliative careNauseaHealth Toxicology and MutagenesisSymptomlcsh:MedicineDiseaseAnxietyPalliative Care.Article03 medical and health sciences0302 clinical medicineInternal medicineNeoplasmsMedicineHumansIn patient030212 general & internal medicineProspective StudiesDepression (differential diagnoses)Clinical Trials as Topicpalliative carebusiness.industrylcsh:RPublic Health Environmental and Occupational HealthCancermedicine.diseaseProspective StudieItaly030220 oncology & carcinogenesisNeoplasmAnxietyCancer patientsymptomsObservational studyFemalemedicine.symptombusinesscancer patientsHumanInternational Journal of Environmental Research and Public Health
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Risk Factors, Lifestyle and Prevention among Adolescents with Idiopathic Juvenile Scoliosis: A Cross Sectional Study in Eleven First-Grade Secondary …

2021

Adolescent idiopathic scoliosis (AIS) has an incidence of 2–3% in the general population and a multifactorial etiology. The present study aims to analyze modifiable risk factors and their interactions in the development of AIS in order to increase knowledge about the disease and to prevent the evolution of AIS in young students with tailored public health strategies. A cross-sectional study was conducted over two consecutive school years among students attending 11 first-grade secondary schools in the province of Palermo, Italy. A self-administered questionnaire that investigated socio-demographical, physical and anamnestic characteristics and habits, focusing on possible risk factors…

medicine.medical_specialtyPediatricsAdolescentCross-sectional studyHealth Toxicology and MutagenesisPopulationback painScoliosisArticleidiopathic adolescent scoliosidysmorphism of the developmental ageRisk FactorsmedicineBack painHumanseducationChildLife Styleidiopathic adolescent scoliosis; risk factors; first-grade secondary school student; back pain; high risk sport; dysmorphism of the developmental age; preventive strategieseducation.field_of_studySchoolsCobb anglebusiness.industryPublic healthIncidence (epidemiology)Public Health Environmental and Occupational HealthRhigh risk sportmedicine.diseaseidiopathic adolescent scoliosisCross-Sectional Studiesfirst-grade secondary school studentrisk factorScoliosisEtiologyMedicinemedicine.symptombusinesspreventive strategiesInternational journal of environmental research and public health
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Family Context Assessment in Middle Childhood: A Tool Supporting Social, Educational, and Public Health Interventions

2021

Quality of the family context has an important role in the physical and mental health of children

medicine.medical_specialtyPsychometricsHealth Toxicology and Mutagenesismedia_common.quotation_subjectassessmentConcurrent validitylcsh:MedicineContext (language use)family contextArticlemiddle childhoodDevelopmental psychologyPromotion (rank)Surveys and QuestionnairesmedicineHumans0501 psychology and cognitive sciencesChildmedia_commonvalidationParentingPublic health05 social scienceslcsh:RPublic Health Environmental and Occupational Health050301 educationSocial environmentReproducibility of ResultsChild developmentMental healthConfirmatory factor analysisMental Healthpositive parentingEducational StatusFemalePublic HealthPsychology0503 education050104 developmental & child psychology
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A Review of Healthcare Failure Mode and Effects Analysis (HFMEA) in Radiotherapy

2016

This paper presents a review of risk analyses in radiotherapy (RT) processes carried out by using Healthcare Failure Mode Effect Analysis (HFMEA) methodology, a qualitative method that proactively identifies risks to patients and corrects medical errors before they occur. This literature review was performed to provide an overview of how to approach the development of HFMEA applications in modern RT procedures, comparing recently published research conducted to support proactive programs to identify risks. On the basis of the reviewed literature, the paper suggests HFMEA shortcomings that need to be addressed.

medicine.medical_specialtyRadiology Nuclear Medicine and ImagingEpidemiologyHealth Toxicology and MutagenesisMEDLINESensitivity and Specificity030218 nuclear medicine & medical imagingrisk estimate03 medical and health sciences0302 clinical medicineNeoplasmsHealth caremedicineHumansMedical physicsHealthcare Failure Mode and Effect Analysisrisk analysiRadiation InjuriesradiotherapySettore ING-IND/19 - Impianti NucleariRadiation medicalMedical Errorsbusiness.industryReproducibility of ResultsSurvival Rate030220 oncology & carcinogenesisbusinessFailure mode and effects analysis
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Tissue bioaccumulation patterns, xenobiotic biotransformation and steroid hormone levels in Atlantic salmon (Salmo salar) fed a diet containing perfl…

2011

In the present study, groups of juvenile Atlantic salmon (Salmo salar) were fed gelatine capsules containing fish-food spiked with PFOA or PFOS (0.2 mg kg(-1) fish) and solvent (methanol). The capsules were given at days 0, 3 and 6. Blood, liver and whole kidney samples were collected prior to exposure (no solvent control), and at days 2, 5, 8 and 14 after exposure (Note: that day 14 after exposure is equal to 7d recovery period). We report on the differences in the tissue bioaccumulation patterns of PFOS and PFOA, in addition to tissue and compound differences in modulation pattern of biotransformation enzyme genes. We observed that the level of PFOS and PFOA increased in the blood, liver …

medicine.medical_specialtyReceptors SteroidEnvironmental EngineeringHydrocortisoneTranscription GeneticCYP3AEstroneHealth Toxicology and MutagenesisSalmo salarEstroneBiologyKidneyXenobioticschemistry.chemical_compoundInternal medicineMethyltestosteronemedicineCytochrome P-450 CYP1A1Environmental ChemistryAnimalsCytochrome P-450 CYP3ATestosteroneMethyltestosteroneBiotransformationGlutathione TransferaseFluorocarbonsPublic Health Environmental and Occupational HealthPregnane X ReceptorKidney metabolismGeneral MedicineGeneral ChemistryPollutionPerfluorooctaneEndocrinologychemistryAlkanesulfonic AcidsLiverBioaccumulationToxicityCaprylatesXenobioticmedicine.drugChemosphere
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Muscle Strength and Physical Performance Are Associated with Reaction Time Performance in Older People

2021

Background: Functional mobility and muscle strength are well known risk factors for sarcopenia. Furthermore, possible associations have been suggested between predisposing factors of sarcopenia and reaction time among the elderly. This study aims to analyze possible associations of functional mobility and muscle strength and reaction times in a population of people aged &gt

medicine.medical_specialtySarcopeniaHealth Toxicology and MutagenesisPopulationPhysical fitnessAnciano030209 endocrinology & metabolismPhysical functionelderlyArticlesarcopenia03 medical and health sciences0302 clinical medicinePhysical medicine and rehabilitationphysical functionReaction TimeMedicineHumans030212 general & internal medicineMuscle StrengtheducationMuscle SkeletalAgededucation.field_of_studyInflamaciónHand Strengthbusiness.industryPublic Health Environmental and Occupational HealthRPhysical Functional Performancemusculoskeletal systemmedicine.diseaseConfidence intervalCross-Sectional StudiesPhysical performanceNutriciónSarcopeniaMuscle strengthphysical fitnessreaction timesMedicinebusinessOlder peopleDesarrollo fisiológicohuman activitiesInternational Journal of Environmental Research and Public Health
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