Search results for " need"

showing 10 items of 648 documents

Stereotactic biopsies guided by an optical navigation system: technique and clinical experience.

2002

Frame-based stereotactic biopsies are time-consuming procedures making necessary head fixation in a ring, explicit coordinate calculation and setting of the parameters. Frameless systems make many of these intermediate steps unnecessary, impose less mechanical restrictions regarding access to the lesions, and with slight modifications can be used to perform stereotactic biopsies. A special adaptation designed to fix the holder and the biopsy instrument is described. The neuronavigation optical tracking system of Radionics was used. CT scans were performed with 6 skin markers. Calibration was performed after head fixation in the Mayfield clamp. Mean calibration error was 2.19 +/- 0.81 mm. Th…

AdultMalemedicine.medical_specialtyStereotactic biopsyNeuronavigationTime FactorsAdolescentVisual controlStereotaxic TechniquesBiopsymedicineHumansChildAgedBrain Diseasesmedicine.diagnostic_testbusiness.industryBiopsy NeedleGeneral MedicineMiddle AgedCannulaSurgeryOptical navigationClampSurgery Computer-AssistedRadionicsSurgeryFemaleNeurology (clinical)businessNuclear medicineTomography X-Ray ComputedMinimally invasive neurosurgery : MIN
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Localization of Muscle Edema and Changes on Muscle Contractility After Dry Needling of Latent Trigger Points in the Gastrocnemius Muscle.

2019

Background Myofascial trigger points (TrPs) are hyperirritable spots within taut bands of skeletal muscles that elicit local and referred pain when stimulated. Among the variety of techniques used for treating TrPs, dry needling (DN) is the most commonly applied intervention. The physiological mechanisms underlying the effects of DN remain to be elucidated. Objective To examine changes in skeletal muscle after DN in the area where the TrP is located. Methods We measured in vivo changes that occur in human skeletal muscle one hour after DN over a TrP with magnetic resonance imaging (MRI) and tensiomyography. The study included 18 asymptomatic subjects with a latent TrP in one medial gastrocn…

AdultMalemedicine.medical_specialtyTensiomyographyContractility03 medical and health sciencesGastrocnemius muscleYoung Adult0302 clinical medicineEdemaInternal medicinemedicineEdemaHumansMuscle SkeletalDry needlingmedicine.diagnostic_testbusiness.industrySkeletal muscleTrigger PointsMagnetic resonance imaging030229 sport sciencesGeneral MedicineMuscle stiffnessMagnetic Resonance ImagingAnesthesiology and Pain Medicinemedicine.anatomical_structureEndocrinologyDry NeedlingNeurology (clinical)medicine.symptombusiness030217 neurology & neurosurgeryMuscle ContractionPain medicine (Malden, Mass.)
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Enzyme activities and glycogen concentration in skeletal muscle in alcoholism. The effect of abstinence and physical conditioning.

1974

. Muscle metabolism of chronic alcoholics has been studied using a muscle biopsy technique immediately after a drinking period, after 6–7 days' abstinence and after one month's physical conditioning. The activities of CPK, HK, LDH, MDH and SDH were significantly decreased in musculus vastus lateralis for 1–2 days after an alcoholic debauch. The enzyme activities of the alcoholics, who either had been abstinent for 6–7 days or in addition conditioned for one month, did not differ from those of the controls. The concentration of muscle glycogen was at the same level in both groups, but in bicycle ergometer work of an equal relative intensity the alcoholics used more glycogen than the control …

AdultMalemedicine.medical_specialtyTime Factorsmedia_common.quotation_subjectPhysical fitnessPhysical Exertionchemistry.chemical_compoundMalate DehydrogenaseInternal medicineHexokinaseInternal MedicinemedicineHumansCreatine Kinasemedia_commonchemistry.chemical_classificationMuscle biopsyPhysical Education and TrainingPhysical conditioningGlycogenmedicine.diagnostic_testL-Lactate Dehydrogenasebusiness.industryMusclesBiopsy NeedlePhosphotransferasesSkeletal muscleAbstinenceMiddle AgedSuccinate DehydrogenaseAlcohol OxidoreductasesAlcoholismEndocrinologyEnzymemedicine.anatomical_structurechemistryConditioningbusinessEnergy MetabolismGlycogenActa medica Scandinavica
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Microcirculation in the healing of surgical wounds in the oral cavity.

2013

Abstract. The aim of this research is to evaluate in vivo the characteristics of microcirculation after taking a biopsy sample from the oral mucosa. 20 patients were recruited to the study and all underwent an oral mucosa biopsy for the excision of benign neoformations. The modifications in the oral microcirculation were evaluated in vivo in correspondence to the surgical site through videocapillaroscopy at three different times: 30 min before the biopsy; 48 h after the biopsy; and 7 days after the biopsy. The statistical significance was checked with the Mann–Whitney U-test (P < 0.05). The analysis of videocapillaroscopic patterns showed statistically significant variations relative to the…

AdultMalemedicine.medical_specialtyVideo RecordingMicroscopic AngioscopyFibromaMicrocirculationMicroscopic AngioscopyYoung AdultDouble-Blind MethodIn vivoBiopsymedicineImage Processing Computer-AssistedHumansOral mucosaAgedMouth neoplasmMouthWound Healingoral microcirculationmedicine.diagnostic_testPapillomabusiness.industrySettore BIO/16 - Anatomia UmanaMicrocirculationBiopsy NeedleOptical ImagingSurgical woundvideocapillaroscopysurgical wounds.Middle AgedSurgeryCapillariesTongue Neoplasmsmedicine.anatomical_structureOtorhinolaryngologyLip NeoplasmsSurgeryFemaleMouth NeoplasmsOral SurgerybusinessWound healingFollow-Up StudiesInternational journal of oral and maxillofacial surgery
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Treatment of temporomandibular myofascial pain with deep dry needling

2012

Objectives: The present study was designed to evaluate the usefulness of deep dry needling in the treatment of temporomandibular myofascial pain. Study Design: We selected 36 patients with myofascial pain located in the external pterygoid muscle (30 women/6 men, mean age=27 years with SD±6,5). We studied differences in pain with a visual analog scale and range of mandibular movements before and after intervention. Results: We found a statistically significant relationship (p<0,01) between therapeutic intervention and the improvement of pain and jaw movements, which continued up to 6 months after treatment. Pain reduction was greater the higher was the intensity of pain at baseline. Conclusi…

AdultMalemedicine.medical_specialtyVisual analogue scaleAcupuncture Therapystomatognathic systemmedicineHumansGeneral DentistryDry needlingbusiness.industryMyofascial painMean ageTemporomandibular Joint Dysfunction Syndrome:CIENCIAS MÉDICAS [UNESCO]Orofacial Pain - TMJDOtorhinolaryngologyPain reductionExternal Pterygoid MuscleUNESCO::CIENCIAS MÉDICASPhysical therapyResearch-ArticleFemaleSurgeryTemporomandibular Joint Dysfunction SyndromebusinessAfter treatment
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Surgical Treatment of Extravasation Injuries

2005

The authors present their experience of treating anti-cancer drug extravasation by means of a composite surgical technique that consists of infiltration with physiological solution and hyaluronidase and subsequent manual aspiration of solutes alternated with profuse irrigation of the infiltrated area. In the immediate post-op we carry out a medical therapy that consists of calciparine and topic antibiotic and/or steroid creams. Since the year 2000 this technique has been used on 25 patients. We have had neither complications nor scars. Copyright 2005 Wiley-Liss, Inc Surgical treatment of extravasation injuries. Napoli P, Corradino B, Badalamenti G, Tripoli M, Vieni S, Furfaro MF, Cordova A,…

AdultMalemedicine.medical_specialtyantiblastictreatment KeyWords Plus:ANTITUMOR AGENTSextravasation injury; antiblastic; prevention; treatmentANTITUMOR AGENTS; APPROPRIATE MANAGEMENT; TISSUE EXTRAVASATION; HYALURONIDASE [Author Keywords]Drug ExtravasationTherapeutic irrigationScarsAntineoplastic AgentsTISSUE EXTRAVASATIONAPPROPRIATE MANAGEMENTCicatrixpreventionBiopsymedicineHumansCalciparineAuthor Keywords:extravasation injurySurgical treatmentTherapeutic IrrigationAgedRetrospective Studiesmedicine.diagnostic_testbusiness.industryBiopsy NeedleGeneral MedicineHYALURONIDASEMiddle Agedmedicine.diseaseHandExtravasationSurgeryAnti-Bacterial Agentsanticancer drugsTreatment OutcomeOncologyAnesthesiaSurgeryFemalemedicine.symptombusinessInfiltration (medical)Extravasation of Diagnostic and Therapeutic Materials
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Invisible gastric carcinoma detected by random biopsy: long-term results after photodynamic therapy

2008

Background and study aims Gastric cancer diagnosed from routine gastric biopsies without any evidence of a visible lesion and negative repeated biopsies is an infrequent but serious clinical problem for which gastrectomy has usually been recommended, even if operative specimens do not show cancer either. We report on a series of 22 such patients undergoing long-term follow-up after attempted treatment with photodynamic therapy (PDT). Patients and methods 22 patients with invisible gastric cancer (IGC) who presented during a 10-year period (10 men, mean age 56 +/- 15 years) were prospectively included. Initial histopathological findings confirmed by second opinion included 10 well-differenti…

AdultMalemedicine.medical_specialtymedicine.medical_treatmentPhotodynamic therapyGastric carcinomaAdenocarcinomaStomach NeoplasmsBiopsymedicineCarcinomaHumansAgedPhotosensitizing Agentsmedicine.diagnostic_testSignet ring cellbusiness.industryBiopsy NeedleStomachSecond opinionGastroenterologyCancerMiddle Agedmedicine.diseaseSurgeryTreatment OutcomePhotochemotherapyFemaleGastrectomybusinessCarcinoma Signet Ring CellEndoscopy
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Kinin receptor status in normal and inflammed gastric mucosa

1997

No documented studies have been reported on the presence of B1 and B2 kinin receptors in the mammalian gastric mucosa. This first study aimed to immunolocalise sites of B1 and B2 kinin receptors in the human pyloric gastric mucosa and to evaluate its role in gastritis. Biopsies were obtained from patients with dyspepsia during endoscopic examination of the patient. The diagnosis and grading of the gastritis was performed on histological examination. Sections were immunostained for both B1 and B2 receptors using rabbit anti-human B1 and B2 kinin receptor antibodies. Control tissue was obtained from partial gastrectomy specimens, following surgical excision of the antrum for duodenal ulcers. …

AdultReceptor StatusPathologymedicine.medical_specialtyReceptor Bradykinin B2Molecular Sequence DataInflammationBiologyReceptor Bradykinin B1EpitheliumAntibody SpecificityGastroscopyPyloric AntrummedicineGastric mucosaAnimalsHumansAmino Acid SequenceDyspepsiaReceptorAntrumBradykinin Receptor AntagonistsPharmacologyReceptors BradykininBiopsy NeedleKininImmunohistochemistryPrecipitin TestsEpitheliummedicine.anatomical_structureGastric MucosaGastritisRabbitsmedicine.symptomGastritisFluorescein-5-isothiocyanateImmunopharmacology
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Information resources used by patients with inflammatory bowel disease: Satisfaction, expectations and information gaps.

2015

Abstract Background and purpose Information received by IBD patients about their disease is of particular importance. The objective of the study was to determine the information resources these patients used, together with their perceived information gaps and expected preferences. Patients and methods A prospective, observational, cross-sectional study conducted on IBD patients attending 13 Spanish hospitals during 2008. Patients completed a semi-structured 52-question survey. Results Survey was adequately completed by 379 of 385 patients (98%), of whom 57% had Crohn's disease and 43% ulcerative colitis. Mean patient age was 37.9 years (range, 16–76 years). Gastroenterologists were the most…

Adultmedicine.medical_specialtyAdolescentGeneral PracticeInformation Seeking BehaviorInformation needsDiseaseInflammatory bowel diseaseNurse's RoleYoung AdultPatient Education as TopicPatient ageSurveys and QuestionnairesmedicineHumansProspective StudiesPhysician's RoleAgedInternetHepatologybusiness.industryGastroenterologyMiddle Agedmedicine.diseaseInflammatory Bowel DiseasesUlcerative colitisSurgerySelf-Help GroupsCross-Sectional StudiesPatient SatisfactionFamily medicineObservational studybusinessGastroenterologia y hepatologia
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Risk of thromboembolism with thrombopoietin receptor agonists in adult patients with thrombocytopenia: systematic review and meta-analysis of randomi…

2012

Background and objective: Thrombopoietin receptor (TPOr) agonists (romiplostim and eltrombopag) are a new approach for the treatment of thrombocytopenia-associated conditions. They promote megakaryocyte differentiation, proliferation and platelet production. In the European Union, both are orphan drugs with an indication restricted to splenectomized immune thrombocytopenic purpura patients who are refractory to other treatments. Due to increasing platelet counts, these drugs may represent a risk for thromboembolic complications. We analyzed whether TPOr agonists affect thromboembolisms occurrence in adult thrombocytopenic patients. Materials and methods: We conducted a systematic review and…

Adultmedicine.medical_specialtyMegakaryocyte differentiationRecombinant Fusion ProteinsEltrombopagReceptors FcBenzoateslaw.inventionchemistry.chemical_compoundRandomized controlled triallawRisk FactorsInternal medicineHematologic AgentsThromboembolismmedicinemedia_common.cataloged_instanceHumansEuropean unionmedia_commonRandomized Controlled Trials as TopicRomiplostimbusiness.industryGeneral MedicineNumber needed to harmThrombocytopeniaSurgeryHydrazineschemistryThrombopoietinMeta-analysisRelative riskPyrazolesbusinessReceptors Thrombopoietinmedicine.drugMedicina clinica
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