6533b858fe1ef96bd12b640d

RESEARCH PRODUCT

Surgical Treatment of Extravasation Injuries

P NapoliBartolo CorradinoFabio FulfaroM TripoliSalvatore VieniAdriana CordovaFrancesco MoschellaSalvatore VieniGiuseppe Badalamenti

subject

AdultMalemedicine.medical_specialtyantiblastictreatment KeyWords Plus:ANTITUMOR AGENTSextravasation injury; antiblastic; prevention; treatmentANTITUMOR AGENTS; APPROPRIATE MANAGEMENT; TISSUE EXTRAVASATION; HYALURONIDASE [Author Keywords]Drug ExtravasationTherapeutic irrigationScarsAntineoplastic AgentsTISSUE EXTRAVASATIONAPPROPRIATE MANAGEMENTCicatrixpreventionBiopsymedicineHumansCalciparineAuthor Keywords:extravasation injurySurgical treatmentTherapeutic IrrigationAgedRetrospective Studiesmedicine.diagnostic_testbusiness.industryBiopsy NeedleGeneral MedicineHYALURONIDASEMiddle Agedmedicine.diseaseHandExtravasationSurgeryAnti-Bacterial Agentsanticancer drugsTreatment OutcomeOncologyAnesthesiaSurgeryFemalemedicine.symptombusinessInfiltration (medical)Extravasation of Diagnostic and Therapeutic Materials

description

The authors present their experience of treating anti-cancer drug extravasation by means of a composite surgical technique that consists of infiltration with physiological solution and hyaluronidase and subsequent manual aspiration of solutes alternated with profuse irrigation of the infiltrated area. In the immediate post-op we carry out a medical therapy that consists of calciparine and topic antibiotic and/or steroid creams. Since the year 2000 this technique has been used on 25 patients. We have had neither complications nor scars. Copyright 2005 Wiley-Liss, Inc Surgical treatment of extravasation injuries. Napoli P, Corradino B, Badalamenti G, Tripoli M, Vieni S, Furfaro MF, Cordova A, Moschella F. Source Chirurgia Plastica e Ricostruttiva, Dipartimento di Discipline Chirurgiche ed Oncologiche, Università degli Studi di Palermo, Italy. pietronapoli@libero.it Abstract The authors present their experience of treating anti-cancer drug extravasation by means of a composite surgical technique that consists of infiltration with physiological solution and hyaluronidase and subsequent manual aspiration of solutes alternated with profuse irrigation of the infiltrated area. In the immediate post-op we carry out a medical therapy that consists of calciparine and topic antibiotic and/or steroid creams. Since the year 2000 this technique has been used on 25 patients. We have had neither complications nor scars.

10.1002/jso.20248http://hdl.handle.net/10447/5750