Search results for " online"

FICC-Seq: a method for enzyme-specified profiling of methyl-5-uridine in cellular RNA.

2019

AbstractMethyl-5-uridine (m5U) is one the most abundant non-canonical bases present in cellular RNA, and in yeast is found at position U54 of tRNAs where modification is catalysed by the methyltransferase Trm2. Although the mammalian enzymes that catalyse m5U formation are yet to be identified via experimental evidence, based on sequence homology to Trm2, two candidates currently exist, TRMT2A and TRMT2B. Here we developed a genome-wide single-nucleotide resolution mapping method, Fluorouracil-Induced-Catalytic-Crosslinking-Sequencing (FICC-Seq), in order to identify the relevant enzymatic targets. We demonstrate that TRMT2A is responsible for the majority of m5U present in human RNA, and t…

Factors influencing success in the Italian app markets: an empirical analysis

2014

Understanding the Drivers of the Daily App Rank: The Role of Revenue Models

2015

In this paper, based on data from two major app stores (Apple Store and Google Play), we study the role of several revenue models adopted by developers in the success of an app measured in terms of daily rank.

Validation of indicators for implementing an adaptive platform for MOOCs

2017

Personalization techniques are a classic solution recommended by many experts for improving learning. Information and communication technologies and online courses have helped reduce the difficulties teachers face with a diversity of student profiles and a large number of students in a classroom. When these factors are extreme, like in a Massive Open Online Course (MOOC), those techniques may be the solution. However, even the most sophisticated technologies have not solved all the challenges posed by personalized learning, and in cases where teachers are not skilled in the technology they must use, the adaptive systems have only complicated the implementation of online courses. Therefore, …

Communicating Medical Information Online: The Case of Adolescent Health Websites

2020

In recent times, our understanding and practice of public health has been increasingly guided by technological advances generally based on governmental decisions (Green et al. 2009). Not only does the growth of a public system for protecting health hinge upon scientific discovery and dissemination of medical knowledge, but also the World Wide Web has considerably changed the health communication environment. This paper considers the online health information addressed to adolescents. Given that young people have difficulty accessing traditional health services, in theory, the Internet might offer them a more confidential and convenient access to an unprecedented level of information about a…

Do Individual Differences in Cognition and Personality Predict Retrieval Practice Activities on MOOCs?

2020

Online quizzes building upon the principles of retrieval practice can have beneficial effects on learning, especially long-term retention. However, it is unexplored how interindividual differences in relevant background characteristics relate to retrieval practice activities in e-learning. Thus, this study sought to probe for this research question on a massive open online course (MOOC) platform where students have the optional possibility to quiz themselves on the to-be-learned materials. Altogether 105 students were assessed with a cognitive task tapping on reasoning, and two self-assessed personality measures capturing need for cognition (NFC), and grittiness (GRIT-S). Between-group anal…

Online sexual activities in Hispanic women: A chance for non-heterosexual women?

2020

Abstract:  Sexuality is still modulated by social determinants that promote a passive role for women. In the recent decades, some findings have supported the influence of the Internet on sexuality. However, the relevance of online sexual activities for some groups such as Hispanic young women is still unknown. In this context, this study examines online sexual experience among 310 Hispanic women from Argentina, Mexico and Spain; as well as the role of their offline sexuality and country in this sexual pattern. As a result, Hispanic women report a variety of online sexual activities that ranges from searching information to masturbation. In particular, the Internet use for sexual purposes is…

The development and status of the IGISOL technique

1997

Abstract The development of the IGISOL technique since its earliest beginnings at the University of Jyvaskyla in the early '80s is reviewed. The processes involved in ion survival in the ion guide are discussed. The design and performance of ion guides for different types of reactions is summarised. The mass-separated beam quality for different skimmer systems is compared.

Probing the Merits of Different Event Parameters for the Identification of Light Charged Particles in CHIMERA CsI(Tl Detectors With Digital Pulse Sha…

2013

We investigated the merits of different event parameters in the identification of Light Charged Particles (LCPs) with CsI(Tl) scintillators read out by photodiodes at high incident energy (400 MeV/u). This investigation is made possible by digital signal processing the output signals. As in the conventional analogue case, the digitized signals allow the discrimination of light charged particles by computing the fast and slow components. In addition other identification parameters as the rise time of the output pulses of the CsI(Tl) come out nearly for free. Aim of this paper is the investigation of novel identification plots and the probe of their merits, in particular at relativistic energ…

A novel approach to measure the cross section of the 18O(p, α)15N resonant reaction in the 0-200 keV energy range

2009

The 18O(p, ?)15N reaction is of primary importance to pin down the uncertainties, due to nuclear physics input, affecting present-day models of asymptotic giant branch stars. Its reaction rate can modify both fluorine nucleosynthesis inside such stars and oxygen and nitrogen isotopic ratios, which allow one to constrain the proposed astrophysical scenarios. Thus, an indirect measurement of the low-energy region of the 18O(p, ?)15N reaction has been performed to access, for the first time, the range of relevance for astrophysical application. In particular, a full, high-accuracy spectroscopic study of the 20 and 90 keV resonances has been performed and the strengths deduced to evaluate the r…