Search results for " organi"
showing 10 items of 10227 documents
Le livre audio en bibliothèque de lecture publique : dispositifs de médiation et formes de prescription d’un support « mineur »
2019
International audience; À partir d’une enquête sur les discours et pratiques liés au livre audio du côté d’usagers et de bibliothécaires menée à l’occasion d’un projet de recherche-action dans trois bibliothèques de lecture publique françaises, nous essayons dans cet article de faire avancer la réflexion autour de la notion de prescription, historiquement ancrée dans la figure du bibliothécaire, et de travailler en particulier les écarts entre la prescription d’un format qui reste un impensé de la profession et la médiation d’une expérience d’écoute de la littérature. Cet écart a des conséquences sur la manière dont les « audio lecteurs » parviennent à dire et à partager leurs pratiques. No…
El modelo triaxial de gestión por valores en organizaciones sanitarias: diagnóstico y propuesta de una escala de medida
2020
En entornos turbulentos, donde los niveles de incertidumbre, dinamismo y complejidad son más elevados, las organizaciones necesitan centrar su atención en la gestión de aspectos internos, que puedan ser más estables y controlables. Para las organizaciones sanitarias, la crisis del año 2008, junto con la actual crisis sanitaria, social y económica producida por la Covid-19, resulta fundamental la búsqueda constante de una mayor eficiencia en la gestión de los recursos humanos. La gestión de los valores organizativos es una herramienta imprescindible para lograr una mayor eficiencia y un mejor desempeño en contextos espacialmente complejos, como el sanitario. Esta Tesis pretende, en primer lu…
Synthesis, X-Ray Structure, Tautomerism Aspect, and Chemical Insight of The 3-(1H-Indol-2-yl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazin-6-ol
2021
The 3-(1H-indol-2-yl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazin-6-ol 2 was obtained exclusively in the enol configuration starting from triazolyl-indole derivative 1 and alkyl halo-esters in the presence of K2CO3. Chemical structure elucidations with the aid of physicochemical characterizations were used to predict its molecular structure while single crystal X-ray diffraction technique was used to shed the light on the supramolecular structure of 2. DFT calculations agreed very well with the reported X-ray structure where the most stable form thermodynamically is the enol form. Its optimized geometry agreed very well with the experimental structure where the correlation coefficients betwe…
Dioxomolybdenum(VI) and -Tungsten(VI) Amino Bisphenolates as Epoxidation Catalysts
2016
Low-cost metallate salts Na2MO4·2H2O (M = molybdenum, tungsten) react with a tridentate amine bisphenol bis(2-hydroxy-3-tert-butyl-5-methylbenzyl)methylamine (H2ONOtBu) under ambient conditions in acidic methanol solutions. The reactions lead to the formation of isostructural dioxo complexes [MO2(ONOtBu)(MeOH)]·MeOH in convenient yields. Spectral data as well as X-ray analyses reveal these complexes to be isostructural. Both compounds were tested as catalysts for epoxidation of olefins using cis-cyclooctene, cyclohexene, norbornene and styrene as substrates and tert-butyl hydroperoxide and hydrogen peroxide as oxidants. The molybdenum complex catalyses selectively the oxidation of cis-cyclo…
Organocatalytic Enantioselective Vinylogous Henry Reaction of 3,5-Dimethyl-4-nitroisoxazole with Trifluoromethyl Ketones
2017
The enantioselective vinylogous Henry reaction of 3,5-dimethyl-4-nitroisoxazole with trifluoromethyl ketones employing a bifunctional squaramide organocatalyst has been developed. A series of isoxazole bearing trifluoromethyl-substituted tertiary alcohols, 2-substituted (R)-1,1,1-trifluoro-3-(3-methyl-4-nitroisoxazol-5-yl)propan-2-ols, were obtained under these mild reaction conditions in good yields and moderate to good enantioselectivities
Acid–base properties of functionalised tripodal polyamines and their interaction with nucleotides and nucleic acids
2010
Novel, highly positively charged tripodal polyamines with appended heterocyclic moieties revealed an intriguing panel of protonation species within the biologically relevant range. Studied compounds bind nucleotide monophosphates by mostly electrostatic interactions but only the imidazole analogue showed selectivity toward UMP in respect to other nucleotides. Strong binding of all the studied compounds to both ds-DNA and ds-RNA is to some extent selective toward the latter, showing rather rare RNA over DNA preference.
Trīsgadīgu bērnu dialogrunas pilnveide dienas ritumā
2019
Kvalifikācijas darbs izstrādāts par tematu „Trīsgadīgu bērnu dialogrunas pilnveide dienas ritumā”. Pētījuma aktualitāti pamatoja apstāklis, ka līdz ar pāreju uz jauno izglītības saturu, tiek izvirzītas jaunas prasības pret tādām bērna kompetencēm kā komunikatīvā, kas ietver dialoga veidošanu un sadarbību. Tai pat laikā dialogrunas attīstības jautājumi pirmsskolas pedagoģijā ir aplūkoti nepietiekami. Pētījuma mērķis ir teorētiski un praktiski pētīt dialogrunas pilnveides iespējas trīsgadīgiem bērniem pirmsskolas organizētā dienas ritumā. Lai sasniegtu šo mērķi, darba teorētiskajā daļā, balstoties uz tādu pedagogu pētījumiem kā N. Andiema (2016), S. Gardners (2016), AJ. Kopilova (Копылова, 20…
An experimental and theoretical study of a heptacoordinated tungsten(VI) complex of a noninnocent phenylenediamine bis(phenolate) ligand
2018
Abstract [W(N2O2)(HN2O2)] (H4N2O2 = N,N′-bis(3,5-di-tert-butyl-2-hydroxyphenyl)-1,2-phenylenediamine) with a noninnocent ligand was formed by reaction of the alkoxide precursor [W(eg)3] (eg = the 1,2-ethanediolate dianion) with two equivalents of ligand. The phenol groups on one of the ligands are completely deprotonated and the ligand coordinates in a tetradentate fashion, whereas the other ligand is tridentate with one phenol having an intact OH group. The molecular structure, magnetic measurements, EPR spectroscopy, and density functional theory calculations indicate that the complex is a stable radical with the odd electron situated on the tridentate amidophenoxide ligand. The formal ox…
On the mechanism of imine elimination from Fischer tungsten carbene complexes
2016
(Aminoferrocenyl)(ferrocenyl)carbene(pentacarbonyl)tungsten(0) (CO)5W=C(NHFc)Fc (W(CO)5(E-2)) is synthesized by nucleophilic substitution of the ethoxy group of (CO)5W=C(OEt)Fc (M(CO)5(1Et)) by ferrocenyl amide Fc-NH– (Fc = ferrocenyl). W(CO)5(E-2) thermally and photochemically eliminates bulky E-1,2-diferrocenylimine (E-3) via a formal 1,2-H shift from the N to the carbene C atom. Kinetic and mechanistic studies to the formation of imine E-3 are performed by NMR, IR and UV–vis spectroscopy and liquid injection field desorption ionization (LIFDI) mass spectrometry as well as by trapping experiments for low-coordinate tungsten complexes with triphenylphosphane. W(CO)5(E-2) decays thermally i…
Roles of Exogenous Technologies in Vehicle Innovation: Cases from a Japan’s Automotive Parts Manufacturing Firm
2017
This paper explores the roles of technological innovations in the growth of Japan’s motor vehicle industry, mainly from technology spillover perspective from the early 2000s to today. An empirical analysis focusing on business performances, R&D investments, and patent applications taking a noteworthy unique case in Japan was attempted. Empirical analyses on the productivity of patent to technology stock, use of exogenous technologies for their own technological innovation on its Automotive Business Unit elucidated that innovation capabilities, incorporation of exogenous technologies, and profit generation makes a virtuous cycle of continuous technological innovation. Furthermore, we fou…