Search results for " pair"

showing 10 items of 779 documents

A low repeat length in oligodendrocyte chromatin

1985

Abstract: The behavior of oligodendrocyte chromatin after micrococcal nuclease digestion of nuclei was assayed in brains of rats of four different ages. During oligodendrocyte differentiation, a decreasing sensitivity of the chromatin to enzymatic attack was observed. On the other hand, the nucleosomal repeat length showed a slight tendency to increase during development. It is worth noting that even the highest values reported here for “oligodendrocyte’ chromatin repeat lengths are significantly lower than 200 base pairs, the value previously reported by others for “non‐astrocytic glia.” Copyright © 1985, Wiley Blackwell. All rights reserved

Base pairCellular differentiationFluorescent Antibody TechniqueOligodendrocyte differentiationBiochemistryCellular and Molecular NeuroscienceSettore BIO/10 - BiochimicamedicineAnimalsMicrococcal NucleaseNucleosomeRepetitive Sequences Nucleic AcidElectrophoresis Agar GelGeneticsNucleosomal Repeat LengthbiologyAge FactorsOligodendrocyte differentiationDNAMolecular biologyChromatinOligodendrocyteNucleosomesRatsChromatinOligodendrogliamedicine.anatomical_structureLiverbiology.proteinSettore MED/26 - NeurologiaNucleosomal repeat lengthNeurogliaBrain StemMicrococcal nuclease
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DNA condensation with spermine dendrimers: interactions in solution, charge inversion, and morphology control

2011

In this report, we characterize the formation of structured condensates of 884 base pair, double stranded DNA and spin-labeled, second generation dendrons (SL-G2) that are spermine-based and cationic using continuous wave electron paramagnetic resonance spectroscopy (CW EPR) and transmission electron microscopy (TEM). The electrostatic interaction between DNA and SL-G2 in solution leads to condensation of DNA into densely packed structures. At a particular charge ratio of 2.3 (cationic charges/anionic charges), the structures appear as thick rod-like condensates of parallelly ordered, stretched DNA and SL-G2. Depending on the concentration of DNA, the charge ratio and the ionic strength, wh…

Base pairChemistryAnalytical chemistryC-DNAGeneral ChemistryCondensed Matter PhysicsDNA condensationIonlaw.inventionCrystallographychemistry.chemical_compoundIonic strengthlawMoleculeElectron paramagnetic resonanceDNASoft Matter
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Usefulness of omp1 restriction mapping for avian Chlamydia psittaci isolate differentiation

1995

Abstract Sixty-five avian Chlamydia psittaci isolates collected worldwide, including 27 previously characterized reference strains, were analysed by restriction mapping of the major outer membrane protein gene ( omp1 ) obtained after DMA amplification by PCR. They were compared to 2 ruminant isolates, a feline pneumonitis and a guinea pig inclusion conjunctivitis (GPIC) isolate. According to their omp1 restriction patterns, avian strains were heterogeneous in that they exhibited 6 and 4 distinct patterns using Alu I and Mbo II restriction enzymes, respectively, thus defining 7 groups. However, 84% of the studied strains belonged to groups 1 to 4, which share a specific fragment triplet of 4…

Base pairGuinea PigsRestriction MappingAMPLIFICATION CHAINE POLYMERASEIn Vitro TechniquesMicrobiologyBirdsRestriction mapAnimalsMolecular BiologyGene[SDV.MP] Life Sciences [q-bio]/Microbiology and ParasitologyElectrophoresis Agar GelChlamydia psittaciGeneticsbiologyDNA–DNA hybridizationGene AmplificationGeneral Medicinebiology.organism_classificationRestriction enzyme[SDV.MP]Life Sciences [q-bio]/Microbiology and ParasitologyChlamydophila psittaciGenes BacterialGenetic markerCatsCattleRestriction fragment length polymorphismBacterial Outer Membrane Proteins
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The selective synthesis of metallanucleosides and metallanucleotides: a new tool for the functionalization of nucleic acids.

2012

Nucleobases team up: the efficient and selective preparation of purine-derived metallanucleosides, metallanucleotides, and metalladinucleotides having M-C bonds (M=Ir(III), Rh(III)) is reported for the first time. The results presented may be applied to the synthesis of functionalized nucleic acids, or DNA/RNA-modified segments.

Base pairMetalationchemistry.chemical_elementIridiumCatalysisNucleobaseRhodiumchemistry.chemical_compoundNucleic AcidsOrganic chemistryRhodiumBase PairingPurine NucleotidesBase SequenceChemistryOrganic ChemistryRNAGeneral ChemistryDNAPurine NucleosidesCombinatorial chemistryMetalsNucleic acidSurface modificationRNADNAChemistry (Weinheim an der Bergstrasse, Germany)
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Toward the development of metal-based synthetic nucleases: DNA binding and oxidative DNA cleavage of a mixed copper(II) complex with N-(9H-purin-6-yl…

2009

Abstract The complex [Cu(N9-ABS)(phen) 2 ]·3.6H 2 O, H 2 N9-ABS  = N -(9 H -purin-6-yl)benzenesulfonamide and phen = 1,10-phenanthroline, has been synthesized and then characterized with the aid of X-ray diffraction, analytical, and spectroscopic techniques. The geometry of Cu(II) is distorted square pyramidal with the equatorial positions occupied by three N atoms from two phenantroline molecules and one N atom from the adenine ring of the sulfonamide ligand. The interaction of the complex with DNA was studied by means of viscosity measurements and fluorescence spectroscopy. The results pointed to a classic intercalation of the complex between the DNA base pairs. The complex was found to b…

Base pairStereochemistryIntercalation (chemistry)Antineoplastic AgentsApoptosisCleavage (embryo)BiochemistryJurkat cellsInorganic ChemistryJurkat Cellschemistry.chemical_compoundOrganometallic CompoundsHumansDNA CleavageCytotoxicitySulfonamidesChemistryDNASquare pyramidal molecular geometryProto-Oncogene Proteins c-bcl-2ApoptosisCaco-2 CellsTumor Suppressor Protein p53CopperDNAPhenanthrolinesJournal of Inorganic Biochemistry
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Docking of indolo- and pyrrolo-pyrimidines to DNA. New DNA-interactive polycycles from amino-indoles/pyrroles and BMMA

2004

New indolo- and pyrrolo-pyrimidines of type 1-4 were studied for their ability to form stable complexes with DNA fragments. The calculated free energies of binding were found in the range -8.39 ÷ -16.72 Kcal/mol. The docking studies revealed a common binding mode with the chromophore intercalated between GC base pairs whereas the side chain lies along the minor groove.

Base pairStereochemistryOrganic ChemistryChromophoreSettore CHIM/08 - Chimica Farmaceuticalcsh:QD241-441chemistry.chemical_compoundlcsh:Organic chemistrychemistryDocking (molecular)Docking DNA interaction indolopyrimidine pyrrolopyrimidine aminoindoles aminopyrroles BMMASide chainFree energiesDNAMinor groove
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"Table 12" of "Search for pair production of higgsinos in final states with at least three $b$-tagged jets in $\sqrt{s} = 13$ TeV $pp$ collisions usi…

2018

Particle-level acceptance for the high-mass discovery signal regions SR-4b-meff1-A-disc and SR-3b-meff3-A, shown as a function of higgsino mass. The acceptance is defined as the fraction of signal events passing the particle-level event selection that emulates the detector-level selection. The acceptance calculation considers only those signal events where both higgsinos decay to Higgs bosons that subsequently both decay to b-quarks.

Beauty13000.0Proton-Proton ScatteringHiggs pair ProductionP P --> HIGGSINO HIGGSINO X --> HIGGS HIGGS NEUTRALINO NEUTRALINO X --> BQ BQBAR BQ BQBAR XHigh Energy Physics::PhenomenologySUSYHigh Energy Physics::ExperimentHiggsinoSupersymmetrySIGHiggs
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"Table 10" of "Search for pair production of higgsinos in final states with at least three $b$-tagged jets in $\sqrt{s} = 13$ TeV $pp$ collisions usi…

2018

Particle-level acceptance for the low-mass discovery signal regions low-SR-MET0-meff440 and low-SR-MET150-meff440, shown as a function of higgsino mass. The acceptance is defined as the fraction of signal events passing the particle-level event selection that emulates the detector-level selection. The acceptance calculation considers only those signal events where both higgsinos decay to Higgs bosons that subsequently both decay to b-quarks.

Beauty13000.0Proton-Proton ScatteringHiggs pair ProductionP P --> HIGGSINO HIGGSINO X --> HIGGS HIGGS NEUTRALINO NEUTRALINO X --> BQ BQBAR BQ BQBAR XHigh Energy Physics::PhenomenologySUSYHigh Energy Physics::ExperimentHiggsinoSupersymmetrySIGHiggs
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"Table 16" of "Search for pair production of higgsinos in final states with at least three $b$-tagged jets in $\sqrt{s} = 13$ TeV $pp$ collisions usi…

2018

Cutflow for low-mass analysis for each signal mass point.

Beauty13000.0Proton-Proton ScatteringHiggs pair ProductionP P --> HIGGSINO HIGGSINO X --> HIGGS HIGGS NEUTRALINO NEUTRALINO X --> BQ BQBAR BQ BQBAR XSUSYHiggsinoSupersymmetrySIGHiggs
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"Table 6" of "Search for pair production of higgsinos in final states with at least three $b$-tagged jets in $\sqrt{s} = 13$ TeV $pp$ collisions usin…

2018

The observed and expected 95% upper limits on the total pair production cross section for degenerate higgsinos as a function of m(higgsino) for the high-mass search. Only the high-mass analysis results are used in this figure.

Beauty13000.0Proton-Proton ScatteringHiggs pair ProductionP P --> HIGGSINO HIGGSINO X --> HIGGS HIGGS NEUTRALINO NEUTRALINO X --> BQ BQBAR BQ BQBAR XSUSYHiggsinoSupersymmetrySIGHiggs
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