Search results for " performance."

High Submicellar Liquid Chromatography

2013

Surfactant addition above the critical micellar concentration (CMC), in reversed-phase liquid chromatography (RPLC), was proposed as a way to modify the selectivity and analysis time, giving rise to a chromatographic mode called micellar liquid chromatography (MLC). However, solutions containing only surfactant are too weak and yield poor peak shape. This was remediated by the addition of a small amount of organic solvent. To preserve the existence of micelles, in MLC high contents of organic solvent are avoided. Nevertheless, there is no reason to neglect the potentiality of mobile phases containing a surfactant above its CMC in water and a high organic solvent content (without micelles). …

Fostering Collaborative Governance in Chronic Disease Management Programs: A Dynamic Performance Management Approach

2020

Chronic diseases are the leading cause of disability and mortality in the world and represent a global health emergency due to the increase in frequency and complexity that has been occurring in recent years. The outcomes related to chronic care needs depend on the joint effort of a multi-provider, multi-disciplinary, and multi-professional service network, which operates along a clinical pathway. However, all the different players involved in the provision of services may have different interests and goals derived from their organizational structure and their role in the overall health system. This context of fragmented governance makes performance management of care services problematic. …

Verbal learning and memory and their associations with brain morphology and illness course in schizophrenia spectrum psychoses.

2012

The California Verbal Learning Test and structural brain imaging were administered to 57 subjects with schizophrenia spectrum disorders and 94 controls in a general population sample. Cases had lower semantic cluster scores. Poorer verbal memory strategies were associated with longer duration of illness and heavier use of antipsychotic medication. After controlling for duration of illness, sex, and total gray matter, poorer verbal memory was associated with lower gray matter volume in the cingulate cortex, juxtapositional lobule, right superior temporal gyrus, and precuneus. After controlling for use of antipsychotic medication, there was an association between higher serial clustering and …

Association between cingulum bundle structure and cognitive performance: an observational study in major depression.

2009

AbstractBackgroundMajor depression can be regarded as a systemic neurobehavioral disorder resulting from dysfunction of the limbic-cortical networks. The cingulum bundle represents a major association fiber tract of those networks. The aim of our study was to determine the association of brain structural tissue markers of the cingulum bundle and cognitive function in patients with major depression.MethodsRegion-of-interest-based analyses of the middle-anterior and middle-posterior cingulum bundle fractional anisotropy (FA) and mean diffusivity (MD) using color-coded diffusion-tensor imaging and neuropsychological assessment in 14 patients with major depression.ResultsFA of the middle-anteri…

The durability of basalt fibres reinforced polymer (BFRP) panels for cladding

2015

The study focuses on two basalt composite laminate panels for cladding, produced by means of vacuum bagging technique. In particular, unidirectional and random basalt fabrics, with different areal weights, using epoxy resin as matrix, were used. According to the ISO 15686 methodology for the evaluation of durability, samples were subjected to cycles of artificial aging in climatic chamber and outdoor exposure, carrying out mechanical (i.e. quasi-static and dynamic) and calorimetric tests. The results show the effectiveness over time of produced basalt composite laminates and the initial increase of the mechanical performances after the first steps of accelerated aging.

Effect of in-class group clicker-quiz competition on student final exam performance.

2019

Impact of chaotic dynamics on the performance of metaheuristic optimization algorithms : An experimental analysis

2022

Random mechanisms including mutations are an internal part of evolutionary algorithms, which are based on the fundamental ideas of Darwin's theory of evolution as well as Mendel's theory of genetic heritage. In this paper, we debate whether pseudo-random processes are needed for evolutionary algorithms or whether deterministic chaos, which is not a random process, can be suitably used instead. Specifically, we compare the performance of 10 evolutionary algorithms driven by chaotic dynamics and pseudo-random number generators using chaotic processes as a comparative study. In this study, the logistic equation is employed for generating periodical sequences of different lengths, which are use…

In vitro P-glycoprotein efflux inhibition by atypical antipsychotics is in vivo nicely reflected by pharmacodynamic but less by pharmacokinetic chang…

2011

Abstract Background P-glycoprotein (P-gp), an efflux transporter of the blood–brain barrier, limits the access of multiple xenobiotics to the central nervous system (CNS). Thus drug-dependent inhibition, induction or genetic variation of P-gp impacts drug therapy. Methods We investigated atypical antipsychotics and their interaction with P-gp. Amisulpride, clozapine, N-desmethylclozapine, olanzapine, and quetiapine were assessed in vitro on their inhibitory potential and in vivo on their disposition in mouse serum and brain, and behaviourally on the RotaRod test. In vivo wildtype (WT) and mdr1a/1b double knockout mice (mdr1a/1b (−/−, −/−); KO) were investigated. Results In rhodamine 123 eff…

Effects of a Complex Physical Activity Program on Children’s Arithmetic Problem Solving and Arithmetic Reasoning Abilities

2023

Research has shown that higher levels of physical activity are associated with better cognitive performance in children. However, the benefits of physical activity on academic achievement and specifically on mathematics performance need to be further explored. Therefore, this study aimed to investigate the effects of a complex physical activity (CPA) intervention program, including cognitive involvement, on children’s mathematics performance. The participants were 128 children (aged 12–13 years) attending third grade in three middle schools. They were randomly allocated into a CPA intervention (n = 64) or a waitlist control group (n = 64), the latter of which was given a regular…

L’adempimento in natura alla luce della riforma del code civil

2018

Il code civil riformato ha integralmente riscritto la disciplina dell’inexécution du contrat, tra le altre cose riconoscendo espressamente il rimedio dell’adempimento in natura, ossia l’exécution forcée en nature, e riservandogli una compiuta disciplina. Così è stato possibile superare l’angusta formulazione originaria del code civil in materia e recepire nel codice soluzioni che, nonostante le indicazioni di segno contrario offerte dalla sua precedente versione, si erano lentamente affermate tanto in dottrina quanto in giurisprudenza, anche per effetto degli influssi provenienti dagli altri sistemi giuridici continentali e dal diritto privato europeo. L’illustrazione del nuovo sistema fran…