Search results for " potential"
showing 10 items of 2713 documents
Relaxion Stars and their detection via Atomic Physics
2019
The cosmological relaxion can address the hierarchy problem, while its coherent oscillations can constitute dark matter in the present universe. We consider the possibility that the relaxion forms gravitationally bound objects that we denote as relaxion stars. The density of these stars would be higher than that of the local dark matter density, resulting in enhanced signals in table-top detectors, among others. Furthermore, we raise the possibility that these objects may be trapped by an external gravitational potential, such as that of the Earth or the Sun. This leads to formation of relaxion halos of even greater density. We discuss several interesting implications of relaxion halos, as …
Amphiphilic poly(hydroxyethylaspartamide) derivative-based micelles as drug delivery systems for ferulic acid
2008
Self-assembling micelles, potentially useful as drug delivery systems for ferulic acid (FA), were obtained in aqueous media from amphiphilic alpha,beta-poly(N-2-hydroxyethyl)-dl-aspartamide (PHEA) copolymers bearing at the polyamino acidic backbone both poly(ethyleneglycol) (2000 or 5000 Da) and hexadecylamine (C(16)) moieties, at a concentration of 7 x 10(- 3) and 4 x 10(- 3) g/l, respectively, with nanometre size and negative zeta potential. These micelles were able to entrap FA and to release it in a prolonged way in phosphate buffer solution at pH 7.4 and human plasma. These systems were also stable in storage conditions and have no cytotoxic effects on Caco-2, 16 HBE, HuDe and K562 cel…
FERULIC ACID INHIBITS OXIDATE STRESS AND CELL DEATH INDUCED BY Ab OLIGOMERS: IMPROVED DELIVERY BY SOLID LIPID NANOPARTICLES.
2009
Oxidative stress and dysfunctional mitochondria are among the earliest events in AD, triggering neurodegeneration. The use of natural antioxidants could be a neuroprotective strategy for blocking cell death. Here, the antioxidant action of ferulic acid (FA) on different paths leading to degeneration of recombinant beta-amyloid peptide (rAbeta42) treated cells was investigated. Further, to improve its delivery, a novel drug delivery system (DDS) was used. Solid lipid nanoparticles (SLNs), empty or containing ferulic acid (FA-SNL), were developed as DDS. The resulting particles had small colloidal size and highly negative surface charge in water. Using neuroblastoma cells and rAbeta42 oligome…
Counselling toward reducing alcohol use, knowledge about its morbidity and personal consumption among students of medical and dental courses in north…
2021
Background Alcohol use disorder (AUD) is directly linked to high-risk consumption. Healthcare students have a crucial role to play in its prevention and management. The aim of this study is to analyse alcohol consumption, as well as to consider the knowledge and attitudes regarding morbidity, and the stage of change when providing assistance to quit AUD. Material and Methods A cross-sectional study was conducted among Dentistry and Medical students using specific and validated questionnaires in an anonymous and voluntary way. Initially, 925 students were invited to participate, of them 500 were reached. Results Among them 85.9% suffered from AUD of whom 75% were women (p<0.001), and it was …
Effective-Lagrangian formulation of generalized vector dominance. II
1975
As in a preceding paper we generalize the Lagrangian of Lee and Zumino to include several mutually interacting vector mesons. The treatment is more general in the sense that all possible interactions between the vector mesons, compatible with the field-current proportionality relations, are now discussed. It is moreover demonstrated that also the fields corresponding to the physical vector mesons satisfy a field-current proportionality relation of exactly the same form. Comparison of the different schemes and their implications for the magnetic moments of the vector mesons are discussed.
Role of Disorder on the Dynamics of a Nonlinear Model for DNA Thermal Denaturation
1992
The dynamics of thermal denaturation of DNA is a good example in which nonlinearity coexits with disorder. The amplitude of the motions is so high that bonds break and the base sequence is inhomogeneous since it contains the genetic code. Using a simple nonlinear model, we study the role of local inhomogeneities or of extended disorder on the dynamics of the localized excitations and on the denaturation rate by numerical simulations at constrained temperature. Approximate analytical results are obtained for the trapping of the breatherlike excitations by isolated defects and the statistical mechanics of the disordered molecule.
Anomalous Coulomb matrix elements in thef7/2shell
2003
γ decays from high-spin states in the N=Z-1 nucleus 2753Co26 have been identified for the first time. Level energies and Coulomb energy differences between these states and their analogs in its mirror nucleus 53Fe have been compared with large-scale pf shell-model calculations, which offer excellent agreement. New information has been obtained on two-proton Coulomb matrix elements needed in the interpretation. These have been extracted from the data via a number of methods and are shown to exhibit an anomalous behavior for the J=2 coupling.
Experimental constraints on the coupling of the Higgs boson to electrons
2015
In the standard model (SM), the coupling of the Higgs boson to electrons is real and very small, proportional to the electron mass. New physics could significantly modify both real and imaginary parts of this coupling. We discuss experiments which are sensitive to the Higgs-electron coupling and derive the current bounds on new physics contributing to this coupling. The strongest constraint follows from the ACME bound on the electron electric dipole moment (EDM). We calculate the full analytic two-loop result for the electron EDM and show that it bounds the imaginary part of the Higgs-electron coupling to be less than 1.7 x 10^-2 times the SM electron Yukawa coupling. Deviations of the real…
High prevalence of oral potentially malignant disorders and risk factors in a semi-urban brazilian city: a population-based cross-sectional study
2021
Background Oral Potentially Malignant Disorders (OPMDs) are defined as lesions with a greater likelihood of progressing to cancer. Population-based studies that evaluate the prevalence of OPMDs are scarce in Brazil. The aim of the present study was to determine the prevalence of OPMDs and associated risk factors in a semi-urban Brazilian population. Material and Methods This is a cross-sectional study, whose universe included individuals aged 40 years or older residing in a medium-sized city of northeastern Brazil. Data collection was divided into two steps: interview and oral examination. The outcome variable was the presence of OPMDs. The predictor variables were sociodemographic characte…
The Electromotive Behaviour of Single Zinc Crystals
1929
To NATURE of Jan. 12, 1929, p. 49, Paul A. Anderson communicated some measurements of his on the potentials of single crystals of zinc. The investigation of a possible change of the electrochemical potential with the changing density of zinc atoms on different planes of the crystal was also the aim of an experimental research commenced in October 1928 in the Physicochemical Laboratory of the University of Latvia, in Riga, and is now in progress. The results obtained here do not agree with those of Anderson in so far as no difference could be found in the potentials of different, artificially prepared planes of single crystals of zinc against a neutral zinc sulphate solution. It must be admi…