Search results for " precision"

showing 10 items of 145 documents

Reactor antineutrino detection in Double Chooz experiment: Techniques for background reduction

2014

Abstract A crucial task for the Double Chooz reactor antineutrino experiment is the thorough study of the different backgrounds in the detector. Newly developed background reduction techniques minimize the impact of the backgrounds on our sensitivity. Moreover, only a precision and accuracy measurement of the residual background would allow to measure the mixing angle θ 13 with high precision. Neutrino coincidence signals are imitated by signals produced in several others physics processes: accidental coincidences of single events (accidental background), as well as correlated events induced by cosmic muons, including stopping muons, fast neutrons and spallation isotopes Li 9 /He 8 . The Do…

PhysicsNuclear and High Energy PhysicsAccuracy and precisionParticle physicsMuon010308 nuclear & particles physicsCHOOZ[PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex]01 natural sciencesNeutron temperatureCoincidenceNuclear physics13. Climate action0103 physical sciences[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]SpallationNeutrino010306 general physicsNeutrino oscillationComputingMilieux_MISCELLANEOUSbackground neutrino oscillation θ13 reactor
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Precise half-life measurement of the Si-26 ground state

2008

The beta-decay half-life of 26Si was measured with a relative precision of 1.4*10e3. The measurement yields a value of 2.2283(27) s which is in good agreement with previous measurements but has a precision that is better by a factor of 4. In the same experiment, we have also measured the non-analogue branching ratios and could determine the super-allowed one with a precision similar to the previously reported measurements. The experiment was done at the Accelerator Laboratory of the University of Jyvaskyla where we used the IGISOL technique with the JYFLTRAP facility to separate pure samples of 26Si.

PhysicsNuclear and High Energy PhysicsBranching fraction010308 nuclear & particles physicsFOS: Physical sciencesHalf-life01 natural sciencesNuclear physics0103 physical sciencesRelative precisionNuclear Experiment (nucl-ex)010306 general physicsGround stateNuclear ExperimentNuclear Physics
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Ground and excited state charmonium production inp+pcollisions ats=200  GeV

2012

We report on charmonium measurements [J/psi (1S), psi' (2S), and chi(c) (1P)] in p + p collisions at root s = 200 GeV. We find that the fraction of J/psi coming from the feed-down decay of psi' and chi(c) in the midrapidity region (vertical bar y vertical bar < 0: 35) is 9.6 +/- 2.4% and 32 +/- 9%, respectively. We also present the p(T) and rapidity dependencies of the J/psi yield measured via dielectron decay at midrapidity (vertical bar y vertical bar < 0.35) and via dimuon decay at forward rapidity (1.2 < vertical bar y vertical bar < 2.2). The statistical precision greatly exceeds that reported in our previous publication [Phys. Rev. Lett. 98, 232002 (2007)]. The new results are compare…

PhysicsNuclear and High Energy PhysicsParticle physics010308 nuclear & particles physicsHigh Energy Physics::PhenomenologyContext (language use)01 natural sciencesNuclear physicsParticle decayExcited state0103 physical sciencesProduction modelStatistical precisionHigh Energy Physics::ExperimentProduction (computer science)RapidityNuclear Experiment010306 general physicsRelativistic Heavy Ion ColliderPhysical Review D
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QValues of the SuperallowedβEmittersAlm26,Sc42, andV46and Their Impact onVudand the Unitarity of the Cabibbo-Kobayashi-Maskawa Matrix

2006

The $\ensuremath{\beta}$-decay ${Q}_{\mathrm{EC}}$ values of the superallowed beta emitters $^{26}\mathrm{Al}^{m}$, $^{42}\mathrm{Sc}$, and $^{46}\mathrm{V}$ have been measured with a Penning trap to a relative precision of better than $8\ifmmode\times\else\texttimes\fi{}{10}^{\ensuremath{-}9}$. Our result for $^{46}\mathrm{V}$, 7052.72(31) keV, confirms a recent measurement that differed from the previously accepted reaction-based ${Q}_{\mathrm{EC}}$ value. However, our results for $^{26}\mathrm{Al}^{m}$ and $^{42}\mathrm{Sc}$, 4232.83(13) keV and 6426.13(21) keV, are consistent with previous reaction-based values. By eliminating the possibility of a systematic difference between the two t…

PhysicsParticle physicsSystematic differenceUnitarity010308 nuclear & particles physicsCabibbo–Kobayashi–Maskawa matrix0103 physical sciencesGeneral Physics and AstronomyBeta (velocity)Relative precisionAtomic physics010306 general physics01 natural sciencesPhysical Review Letters
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Optical Characterization Method for Tilted or Decentered Intraocular Lenses

2016

Purpose To test and validate a method for measuring the optical quality and optical power of monofocal intraocular lenses (IOLs) in the presence of a tilt or a decentration as well as its optical power. Methods The experimental system consists of an artificial eye (wet-cell) and a commercial aberrometer with a Shack-Hartmann sensor. Optical image quality parameters such as point spread function (PSF), modulation transfer function (MTF), and the simulations of the retinal image of an extended object are computed from the in vitro wavefront data of an IOL. Repeatability and reproducibility of the system are tested. Mathematical and ray-tracing simulations are used to ascertain the precision a…

Point spread functionOptics and PhotonicsAccuracy and precisionMaterials sciencePseudophakiaOptical powerArtificial Lens Implant Migration01 natural sciences010309 optics03 medical and health sciences0302 clinical medicineOpticsLens Implantation IntraocularOptical transfer function0103 physical sciencesHumansLenses IntraocularWavefrontReproducibilitybusiness.industryAberrometryReproducibility of ResultsRepeatabilityModels TheoreticalOphthalmologyTilt (optics)030221 ophthalmology & optometrybusinessOptometryOptometry and Vision Science
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A system for the real-time geo-referenced measurement of soil parameters

2011

The aim of this research is to develop a system for accurately measuring in real-time, collecting and processing a high amount of geo-referenced data of soil physical-mechanical parameters, e.g. cone penetrometer resistance, index of soil compaction, and draft force. The system for measuring the soil cone penetrometer resistance is comprised of a load cell, connected to a rod, ending with a cone, and is mounted on a frame, fixed to the front part of a tractor. The system for measuring the draft force required to till the soil is comprised of a load cell, mounted on the hitch hook of a tool carrier, towed by the tractor. Moreover, in order to test the usefulness of the system with different …

Precision agricultureAgricultural and Biological Sciences (all)penetrometer soil compaction spatial variability precision agricultureSettore AGR/09 - Meccanica AgrariaVeterinary (all)Penetrometer; Precision agriculture; Soil compaction; Spatial variability; Agricultural and Biological Sciences (all); Veterinary (all)PenetrometerSoil compactionSpatial variability
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La Corte costituzionale apre al divieto di retroattività del novum penitenziario in malam partem.

2020

With a courageous judgment, the Constitutional Court extends the application scope of art. 25, par. 2, Cost. in the criminal enforcement sector. Censoring the living law, the Court states the prohibition of the retroactivity of the measures more afflictive introduced by law no. 3 of 2019 to convicts who committed the fact before its entry into force. The Author, after dwelling on the new paradigm of "European legality", retraces the salient passages of the decision, from which it draws the innovative message of the Judge of the laws.

Principle of legality - Italian Constitutional Court - Accessibility foreseeability and precision - Principle of retroactivity - European Union legal order - National laws - Safeguards for the individual - Law no. 3 of 2019 - Art. 25 par. 2 Cost. - Criminal enforcement sector.Settore IUS/16 - Diritto Processuale Penale
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ARIA‐EAACI care pathways for allergen immunotherapy in respiratory allergy

2021

Funding Information: BSreports personal fees from Allergopharma, during the conduct of the study; grants from National Health Programm, grant, personal fees from Polpharma, ASTRA, personal fees from Mylan, Adamed, patient ombudsman, national Centre for Research and Development, Polish Allergology Society. Funding Information: NGP reports personal fees from Novartis, Nutricia, HAL, MENARINI/FAES FARMA, SANOFI, MYLAN/MEDA, BIOMAY, AstraZeneca, GSK, MSD, ASIT BIOTECH, Boehringer Ingelheim, grants from Gerolymatos International SA, Capricare. Funding Information: CA reports grants from Allergopharma, grants from Idorsia, Swiss National Science Foundation, Christine Kühne‐Center for Allergy Rese…

Pulmonary and Respiratory Medicineprecision medicineeducationImmunology610ReviewSettore MED/10 - Malattie Dell'Apparato Respiratorioimmune system diseasesHDE ALERallergic rhinitis ; asthma ; immunotherapy ; precision medicineMedicine and Health SciencesImmunology and Allergy[SDV.IMM.ALL]Life Sciences [q-bio]/Immunology/AllergologyComputingMilieux_MISCELLANEOUSRhinitisallergic rhinitisallergic rhinitis; asthma; immunotherapy; precision medicineasthmaRC581-607respiratory tract diseases3121 General medicine internal medicine and other clinical medicineimmunotherapyImmunologic diseases. Allergy600 Technik Medizin angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit[SDV.IMM.ALL] Life Sciences [q-bio]/Immunology/Allergologyallergic rhinitis asthma immunotherapy precision medicine
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Quantitative and qualitative control of antineoplastic preparations: Gravimetry versus HPLC.

2019

This article compares gravimetry vs. high-performance liquid chromatography (HPLC) as quality control (QC) methods for paclitaxel, docetaxel and oxaliplatin preparations. We aimed at assessing the preparation method reliability in our hospital, evaluating compounding accuracy and estimating the influence of personnel training and standardized homogenization on compounding accuracy. Agreement, correlation, concordance, accuracy and precision between methods were evaluated for each drug. Conforming preparation percentages (CPs) at different tolerance limits (TLs) and compounding accuracy were calculated for each method and drug. Compounding accuracy was compared before and after personnel tra…

Quality ControlAccuracy and precisionPaclitaxelCytostatic agentsAntineoplastic AgentsDocetaxelHigh-performance liquid chromatographyPreparation method03 medical and health sciences0302 clinical medicineMedicineHumansPharmacology (medical)GravimetryChromatography High Pressure LiquidDrug compoundingChromatographybusiness.industryReproducibility of ResultsOncologyDocetaxelCompounding030220 oncology & carcinogenesisbusiness030215 immunologymedicine.drugJournal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners
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Entrectinib: a potent new TRK, ROS1, and ALK inhibitor

2015

Abstract: Introduction: Receptor tyrosine kinases (RTKs) and their signaling pathways, control normal cellular processes; however, their deregulation play important roles in malignant transformation. In advanced non-small cell lung cancer (NSCLC), the recognition of oncogenic activation of specific RTKs, has led to the development of molecularly targeted agents that only benefit roughly 20% of patients. Entrectinib is a pan-TRK, ROS1 and ALK inhibitor that has shown potent anti-neoplastic activity and tolerability in various neoplastic conditions, particularly NSCLC. Areas covered: This review outlines the pharmacokinetics, pharmacodynamics, mechanism of action, safety, tolerability, pre-cl…

Receptor Protein-Tyrosine KinasesEntrectinibNTRK1NTRK2NTRK3Receptor tyrosine kinaseEntrectinibMalignant transformationAntineoplastic AgentNeoplasmsProtein-Tyrosine KinaseALK; colorectal cancer; Entrectinib; non-small cell lung cancer; NTRK1; NTRK2; NTRK3; precision medicine; ROS1; salivary gland cancer; TrkA; TrkB; TrkC; Animals; Antineoplastic Agents; Benzamides; Humans; Indazoles; Neoplasms; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases; Receptor; trkA; Receptor; trkB; Receptor; trkC; Pharmacology; Pharmacology (medical)Anaplastic Lymphoma KinasePharmacology (medical)salivary gland cancerProto-Oncogene ProteinbiologyTrkAPharmacology. TherapyTrkCTrkBGeneral MedicineProtein-Tyrosine KinasesReceptor Protein-Tyrosine KinaseBenzamidesmedicine.symptomROS1ReceptorHumanIndazolesmedicine.drug_classprecision medicineAntineoplastic Agentscolorectal cancerBenzamideProto-Oncogene ProteinsmedicineROS1AnimalsHumansReceptor trkBReceptor trkCReceptor trkAnon-small cell lung cancerPharmacologyAnimalReceptor Protein-Tyrosine KinasesALK inhibitorIndazoleMechanism of actionALKTrk receptorbiology.proteinCancer researchNeoplasmALK; colorectal cancer; Entrectinib; non-small cell lung cancer; NTRK1; NTRK2; NTRK3; precision medicine; ROS1; salivary gland cancer; TrkA; TrkB; TrkC; Animals; Antineoplastic Agents; Benzamides; Humans; Indazoles; Neoplasms; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases; Receptor trkA; Receptor trkB; Receptor trkC; Pharmacology; Pharmacology (medical)Expert Opinion on Investigational Drugs
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