Search results for " press"

showing 10 items of 4213 documents

Beta-adrenergic blocking activity and haemodynamic effects in man of K� 1313, a new beta-adrenergic antagonist

1971

The beta-adrenergic blocking activity and haemodynamic effects of o-[2-hydroxy-3-(isopropylamino)-propoxy]-benzonitril (Ko 1313) have been studied in 22 patients. Antagonism of isoproterenol-induced tachycardia was used as a measure of the beta-adrenergic blocking activity. Ko 1313 1.0 mg had its maximum beta-adrenoceptor blocking effect 5–30 min after intravenous injection. Ko 1313 10.0 mg produced maximum betablockade 1–4 h after oral administration. 1.0 mg Ko 1313 injected intravenously had approximately the same beta-adrenergic blocking effect as 1.0 mg propranolol also given intravenously. After intravenous administration Ko 1313 was 3–4 times as potent as the same dose given orally. A…

AdultTachycardiamedicine.medical_specialtyCardiac outputAdolescentAdrenergic receptorCardiac VolumeAdrenergic beta-AntagonistsAdministration OralBlood Pressure1-PropanolPropranololPharmacologyElectrocardiographyHeart RateOral administrationInternal medicineNitrilesHeart ratemedicineHumansPharmacology (medical)Cardiac OutputPharmacologyBeta-adrenergic blocking agentPropylaminesbusiness.industryHemodynamicsIsoproterenolGeneral MedicineMiddle AgedAmino AlcoholsPropranololDose–response relationshipEndocrinologyInjections IntravenousSympatholyticsVascular Resistancemedicine.symptombusinessmedicine.drugEuropean Journal of Clinical Pharmacology
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The Association of Mediterranean Diet during Pregnancy with Longitudinal Body Mass Index Trajectories and Cardiometabolic Risk in Early Childhood.

2019

Objective To evaluate the associations between maternal adherence to the Mediterranean diet during pregnancy and their offspring's longitudinal body mass index (BMI) trajectories and cardiometabolic risk in early childhood. Study design We included mother-child pairs from the Infancia y Medio Ambiente (INMA) longitudinal cohort study in Spain. We measured dietary intake during pregnancy using a validated food frequency questionnaire and calculated the relative Mediterranean diet score (rMED). We estimated offspring's BMI z score trajectories from birth to age 4 years using latent class growth analyses (n = 2195 mother-child pairs). We measured blood pressure, waist circumference, and cardio…

AdultWaistMediterranean dietOffspringBlood PressureLower riskDiet MediterraneanBody Mass Index03 medical and health sciences0302 clinical medicinePregnancyRisk Factors030225 pediatricsMedicineHumans030212 general & internal medicineLongitudinal StudiesChildPregnancybusiness.industrymedicine.diseaseCardiovascular DiseasesSpainRelative riskChild PreschoolPediatrics Perinatology and Child HealthCohortFemaleWaist CircumferencebusinessBody mass indexDemographyThe Journal of pediatrics
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Comparison of high-pressure liquid chromatography (HPLC) and Griess reagent-spectroscopic methods for the measurement of nitrate in serum from health…

2008

Bioavailability of NO can be estimated by measuring the concentration of nitrate (NO(3)) in serum. However, the methods used for the measurement NO(3) in plasma or serum show a great degree of variation. Therefore, we compared two analytical methods for the measurement of NO(3) in serum.The concentration of NO(3) in 600 serum samples collected from healthy individuals was determined by the HPLC and by the Griess reagent-spectroscopic method.The concentration of NO(3) in the samples was 29.4+/-16.1 micromol/L and 26.2+/-14.0 micromol/L (mean+/-SD) measured by HPLC and Griess reagent-spectroscopic method respectively (p0.0001). We detected a significant correlation between the two methods (R=…

Adultinorganic chemicalsAdolescentClinical BiochemistryHigh-performance liquid chromatographyYoung Adultchemistry.chemical_compoundNitrateGriess testSulfanilamidesHumansHplc methodReference standardsChromatography High Pressure LiquidAgedAged 80 and overNitratesChromatographySpectrum Analysisorganic chemicalsfood and beveragesGeneral MedicineMiddle AgedReference StandardsEthylenediaminesSerum samplesBioavailabilitychemistryHealthy individualsClinical Biochemistry
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Physical fitness profile in female horseback riders.

2019

BACKGROUND: The purpose of the present study was to examine the levels of endurance and neuromuscular performance variables in female horseback riders. METHODS: 52 female Finnish riders were involved (age 29.4±8.9 yrs, height 1.68±0.06 m, weight 67.5±10.0 kg), 19 show-jumping riders (SJ) and 33 eventing riders (E), riding-time minimum of 4 times/week, jumping level of minimum 1.06±0.11m. The measurements were maximal bilateral isometric leg press force (MVCLP), maximal unilateral isometric knee extension (MVCKE) and flexion forces (MVCKF), countermovement jump (CMJ), maximal isometric force of the trunk extensor and flexor muscles (MVCE, MVCF), weight distribution of the body (WD), handgrip…

Adultkestävyysharjoittelu040301 veterinary sciencesStrength trainingPhysical Therapy Sports Therapy and Rehabilitationcombined strength and endurance trainingIsometric exercisemedicine.disease_cause0403 veterinary science03 medical and health sciencesYoung Adultratsastajat0302 clinical medicineJumpingAnimal scienceendurance traininghevosurheiluratsastusHand strengthequestrian sportsstrength trainingmedicineHumansOrthopedics and Sports MedicineMuscle StrengthLeg pressMuscle SkeletalHand Strengthbusiness.industryLactate thresholdVO2 maxResistance Training030229 sport sciences04 agricultural and veterinary sciencesTrunkfyysinen kuntoAthletesPhysical Fitnesshorseback ridingPhysical EnduranceFemalevoimaharjoittelubusinessSportsThe Journal of sports medicine and physical fitness
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Increase in Nocturnal Blood Pressure and Progression to Microalbuminuria in Type 1 Diabetes

2002

Patients with type 1 diabetes mellitus and microalbuminuria often have elevated blood pressure while they are asleep, but it is not known whether the elevation develops concomitantly with microalbuminuria or precedes it.We monitored 75 adolescents and young adults who had had type 1 diabetes with normal urinary albumin excretion and blood pressure for more than five years. Ambulatory blood-pressure monitoring was used to assess blood pressure at the initial evaluation and about two years later, at which time all subjects had normal urinary albumin excretion. Subsequently, subjects were monitored for the development of microalbuminuria.Microalbuminuria developed in 14 subjects, whereas the o…

Adultmedicine.medical_specialtyAdolescentBlood PressureExcretionInternal medicineDiabetes mellitusmedicineAlbuminuriaHumansProspective StudiesGlycated HemoglobinType 1 diabetesProteinuriabusiness.industryAlbuminGeneral MedicineBlood Pressure Monitoring Ambulatorymedicine.diseaseCircadian RhythmDiabetes Mellitus Type 1EndocrinologyBlood pressureAmbulatoryDisease ProgressionCardiologyMicroalbuminuriamedicine.symptombusinessBiomarkersNew England Journal of Medicine
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Influence of early life risk factors and lifestyle on systemic vascular resistance in later adulthood : the cardiovascular risk in young Finns study

2021

Purpose: There are limited data available concerning the effects of lifetime risk factors and lifestyle on systemic hemodynamics, especially on systemic vascular resistance. The purpose of the study was to evaluate how lifetime cardiovascular risk factors (body mass index (BMI), high-density lipoprotein, low-density lipoprotein, triglycerides, systolic blood pressure, blood glucose) and lifestyle factors (vegetable consumption, fruit consumption, smoking and physical activity) predict systemic vascular resistance index (SVRI) and cardiac index (CI) assessed in adulthood. Materials and Methods: Our study cohort comprised 1635 subjects of the Cardiovascular Risk in Young Finns Study followed …

Adultmedicine.medical_specialtyAdolescentCardiac indexHemodynamicsBlood Pressure3121 Internal medicineBody Mass IndexYoung AdultRisk FactorsInternal medicineInternal MedicinemedicineHumansRisk factorChildLife StyleFinlandmedicine.diagnostic_testbusiness.industryGeneral Medicine3126 Surgery anesthesiology intensive care radiologyImpedance cardiographyBlood pressuremedicine.anatomical_structureCardiovascular DiseasesHeart Disease Risk FactorsCohortVascular resistanceFemaleVascular Resistance3111 BiomedicineCardiology and Cardiovascular MedicinebusinessBody mass index
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Acute Endocrine and Force Responses and Long-Term Adaptations to Same-Session Combined Strength and Endurance Training in Women

2015

This study examined acute hormone and force responses and strength and endurance performance and muscle hypertrophy before and after 24 weeks of same-session combined strength and endurance training in previously untrained women. Subjects were assigned 1 of 2 training orders: endurance preceding strength (E + S, n = 15) or vice versa (S + E, n = 14). Acute force and hormone responses to a combined loading (continuous cycling and a leg press protocol in the assigned order) were measured. Additionally, leg press 1 repetition maximum (1RM), maximal workload during cycling (Wmax), and muscle cross-sectional area (CSA) were assessed. Loading-induced decreases in force were significant (p < 0.01–…

Adultmedicine.medical_specialtyAdolescentRepetition maximumPhysical Therapy Sports Therapy and RehabilitationGrowth hormoneQuadriceps MuscleMuscle hypertrophyYoung Adult03 medical and health sciences0302 clinical medicineEndurance trainingInternal medicinemedicineHumansEndocrine systemConcurrent trainingTestosteroneOrthopedics and Sports MedicineMuscle StrengthExercise physiologyta315Leg pressExerciseGrowth hormonePerformance adaptationsTestosteroneUltrasonographyHuman Growth Hormonebusiness.industry030229 sport sciencesGeneral MedicineOrder effectAdaptation PhysiologicalEndocrinologyPhysical EnduranceFemaletestosteronibusiness030217 neurology & neurosurgeryPhysical Conditioning HumanJournal of Strength and Conditioning Research
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Neonatal outcome following long-distance air travel for fetoscopic laser coagulation treatment of twin-to-twin transfusion syndrome

2011

Abstract Objective To investigate the impact of undertaking long-distance air travel to a specialized medical center while pregnant in order to undergo fetoscopic laser coagulation (FLC) for twin-to-twin transfusion syndrome (TTTS). Methods A retrospective cohort study was conducted of women with TTTS who travelled by air (n = 16) or land (n = 61) to the Centre of Perinatal Diagnosis and Microinvasive Fetal Surgery, Mainz, Germany, between January 1, 2006, and December 31, 2010. All women underwent FLC on arrival at the study center. Neonatal outcome, postoperative neonatal survival rates, and rates of adverse effects were recorded. Results The postoperative survival rate for a single twin …

Adultmedicine.medical_specialtyAircraftmedicine.medical_treatmentTwin-to-twin transfusion syndromeFetoscopyMonochorionic twin pregnancyFetoscopic laser coagulationPregnancyGermanyMedicineHumansTertiary care medical centerAdverse effectSurvival rateRetrospective StudiesPregnancyAir PressureTravelLaser Coagulationmedicine.diagnostic_testbusiness.industryObstetricsFetal surgeryFetoscopyTwin-to-twin transfusion syndromeInfant NewbornObstetrics and GynecologyRetrospective cohort studyGeneral MedicineFetofetal Transfusionmedicine.diseaseSurvival RateTreatment OutcomePregnancy TwinFemalebusinessLaser coagulationAir travelInternational Journal of Gynecology & Obstetrics
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Studies on the mechanism of mineralocorticoid-induced blood pressure increase in man.

1979

1. To gain insight into the mechanism of mineralocorticoid-induced blood pressure rise in man we performed haemodynamic studies in six normotensive volunteer subjects before and during administration of the synthetic steroid 9α-fluorocortisol (0·8 mg daily) for a period of 6 weeks. In a further study, performed in seven subjects, plasma noradrenaline concentration and reactivity to exogenous noradrenaline were determined before and during administration of the mineralocorticoid. 2. Within the first week of steroid administration an increase in mean arterial blood pressure could be demonstrated, which was due to an increase in cardiac output. After the sixth week the elevated blood pressure …

Adultmedicine.medical_specialtyCardiac outputSympathetic Nervous SystemEpinephrinemedicine.drug_classmedicine.medical_treatmentHemodynamicsBlood PressureSteroidNorepinephrineHeart RateInternal medicineReninmedicineHumansCardiac OutputVolunteerChemistryAngiotensin IIGeneral MedicineEndocrinologyBlood pressurePressor responseMineralocorticoidFludrocortisoneBlood pressure increaseClinical science (London, England : 1979)
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Intravascular volume therapy in adults guidelines from the association of the scientific medical societies in Germany

2016

No abstract available.

Adultmedicine.medical_specialtyCritical CareHypovolemiaMEDLINEMedizinBlood volumelaw.inventionLactated ringers solution03 medical and health sciences0302 clinical medicineRandomized controlled trial030202 anesthesiologylawGermanymedicineIntravascular volume statusHumansddc:610Intensive care medicineBlood VolumeElective cesarean sectionbusiness.industryCentral venous pressure030208 emergency & critical care medicine3. Good healthAnesthesiology and Pain MedicineFluid Therapybusiness
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