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showing 10 items of 891 documents

Corrigendum: Seabuckthorn Pulp Oil Protects against Myocardial Ischemia–Reperfusion Injury in Rats through Activation of Akt/eNOS

2016

Seabuckthorn (SBT) pulp oil obtained from the fruits of seabuckthorn [Hippophae rhamnoides L. (Elaeagnaceae)] has been used traditionally for its medicinal and nutritional properties. However, its role in ischemia–reperfusion (IR) injury of myocardium in rats has not been elucidated so far. The present study reports the cardioprotective effect of SBT pulp oil in IR-induced model of myocardial infarction in rats and underlying mechanism mediating activation of Akt/eNOS signaling pathway. Male albino Wistar rats were orally administered SBT pulp oil (5, 10, and 20 ml/kg/day) or saline for 30 days. On the day 31, ischemia was induced by one-stage ligation of left anterior descending coronary a…

0301 basic medicinenatural productsIschemia030204 cardiovascular system & hematologyPharmacologyseabuckthornmedicine.disease_causeLipid peroxidation03 medical and health scienceschemistry.chemical_compound0302 clinical medicineEnosLactate dehydrogenaseMedicineoxidative stressPharmacology (medical)Original ResearchPharmacologylehberrybiologybusiness.industrylcsh:RM1-950apoptosisCorrectionbiology.organism_classificationmedicine.diseaseMalondialdehydemyocardial ischemia–reperfusion injury030104 developmental biologylcsh:Therapeutics. PharmacologyBiochemistrychemistryinflammationedible oilPulp (tooth)businessReperfusion injuryOxidative stressFrontiers in Pharmacology
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A Standardized Wedelia chinensis Extract Overcomes the Feedback Activation of HER2/3 Signaling upon Androgen-Ablation in Prostate Cancer

2017

Crosstalk between the androgen receptor (AR) and other signaling pathways in prostate cancer (PCa) severely affects the therapeutic outcome of hormonal therapy. Although anti-androgen therapy prolongs overall survival in PCa patients, resistance rapidly develops and is often associated with increased AR expression and upregulation of the HER2/3-AKT signaling pathway. However, single agent therapy targeting AR, HER2/3 or AKT usually fails due to the reciprocal feedback loop. Previously, we reported that wedelolactone, apigenin, and luteolin are the active compounds in Wedelia chinensis herbal extract, and act synergistically to inhibit the AR activity in PCa. Here, we further demonstrated th…

0301 basic medicinenatural productsmedicine.drug_classPharmacologyurologic and male genital diseasesAntiandrogen03 medical and health scienceschemistry.chemical_compoundProstate cancer0302 clinical medicineHER3HER2LNCaPMedicineEnzalutamidePharmacology (medical)Pharmacologybusiness.industrylcsh:RM1-950apoptosisprostate cancerWedelolactonemedicine.diseaseAndrogenanimal modelsAndrogen receptorlcsh:Therapeutics. Pharmacology030104 developmental biologychemistry030220 oncology & carcinogenesisHormonal therapybusinessFrontiers in Pharmacology
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New strategies for the development of innovative fermented meat products: a review regarding the incorporation of probiotics and dietary fibers

2019

Over the last decades, consumer´s preference for and their attention to food products presented as healthy and with favorable nutritional information has been significantly increased. In this line,...

0303 health sciences03 medical and health sciences0404 agricultural biotechnology030309 nutrition & dieteticsGeneral Chemical EngineeringFood products04 agricultural and veterinary sciencesFood scienceNutritional informationBiology040401 food sciencePreferenceFood ScienceFood Reviews International
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Opuntia Ficus Indica Edible Parts: A Food and Nutritional Security Perspective

2020

Cactus Opuntia ficus indica is widely distributed in (semi-) arid regions. Fruit and cladodes are processed into many food products. Cladodes are used as vegetables, but their main use is flour, wh...

0303 health sciences030309 nutrition & dieteticsbusiness.industryGeneral Chemical EngineeringOpuntia ficus04 agricultural and veterinary sciencesBiologyFood safetybiology.organism_classification040401 food scienceArid03 medical and health sciencesHorticulture0404 agricultural biotechnologyFood productsCactusCladodesbusinessFood ScienceFood Reviews International
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Innovative Green Technologies of Intensification for Valorization of Seafood and Their By-Products

2019

The activities linked to the fishing sector generate substantial quantities of by-products, which are often discarded or used as low-value ingredients in animal feed. However, these marine by-products are a prominent potential good source of bioactive compounds, with important functional properties that can be isolated or up-concentrated, giving them an added value in higher end markets, as for instance nutraceuticals and cosmetics. This valorization of fish by-products has been boosted by the increasing awareness of consumers regarding the relationship between diet and health, demanding new fish products with enhanced nutritional and functional properties. To obtain fish by-product-derived…

030309 nutrition & dieteticsEmerging technologiesmedia_common.quotation_subjectPharmaceutical ScienceCosmeticsReviewCosmetics03 medical and health sciencesIngredient0404 agricultural biotechnologyNutraceuticalinnovative green technologieshigh-added value compoundsDrug DiscoveryFish ProductsAdded valueAnimalsHumansQuality (business)Ultrasonics14. Life underwaterPharmacology Toxicology and Pharmaceutics (miscellaneous)functional foodsmedia_common0303 health sciencesBiological Productsseafood by-productsSupercritical fluid extractionChromatography Supercritical FluidGreen Chemistry Technology04 agricultural and veterinary sciencesFish products040401 food scienceSeafoodDietary SupplementsBiochemical engineeringBusiness
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Salt and Aroma Compound Distributions Influence Flavour Release and Temporal Perception While Eating Hot-Served Flans.

2021

International audience; To counteract the negative effect of salt overconsumption on health, strategies have been developed to reduce the salt content in food products. Among them, two promising strategies based on odour-induced saltiness enhancement and the heterogeneous distribution of flavour compounds were combined and assessed in four-layer cream-based snacks. To investigate the relationship between saltiness enhancement, temporal release and perception of flavour compounds in hot snacks with heterogeneous distribution of salt and aroma compounds, complementary techniques were used: nose space PTR-Tof-MS (Proton Transfer Reaction-Time of Flight–Mass Spectrometry) to assess the release …

030309 nutrition & dieteticsFood HandlingFlavourPharmaceutical ScienceMass SpectrometryAnalytical Chemistrychemistry.chemical_compoundDrug DiscoveryAroma compoundsaltFood science2. Zero hungerchemistry.chemical_classification0303 health sciencesbiologyspatial distributionfood and beveragesTaste Perception04 agricultural and veterinary sciences040401 food scienceTaste intensitytemporal dominance of sensationsChemistry (miscellaneous)TasteMolecular MedicineSalt (chemistry)alternate time intensityArticlelcsh:QD241-44103 medical and health sciences0404 agricultural biotechnologylcsh:Organic chemistryHumansPhysical and Theoretical ChemistrySodium Chloride DietaryAromaflavour releaseOrganic Chemistrybiology.organism_classificationFlavoring AgentschemistryaromaFood productsOdorantsSaltsSalty tastedescriptive sensory analysisTemporal perception[SDV.AEN]Life Sciences [q-bio]/Food and NutritionFood AnalysisMolecules (Basel, Switzerland)
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Pulsed electric field and mild heating for milk processing: a review on recent advances.

2019

Pulsed electric field (PEF) treatment consists of exposing food to electrical fields between electrodes within a treatment chamber, which can improve the preservation of fresh-like products such as milk. Although several studies support the use of PEF technology to process milk at low temperature, these studies reported microbial reductions of around 3 log10 cycles and also indicated a limited impact of PEF on some endogenous and microbial enzymes. This scenario indicates that increasing the impact of PEF on both enzymes and microorganisms remains a major challenge for this technology in milk processing. More recently, combining PEF with mild heating (below pasteurization condition) has bee…

030309 nutrition & dieteticsFood HandlingPasteurizationlaw.invention03 medical and health sciencesFresh milk0404 agricultural biotechnologyMilk productslawAnimalsFood science0303 health sciencesNutrition and Dieteticsbusiness.industryChemistryLiquid foodfood and beverages04 agricultural and veterinary sciencesChemical industry040401 food scienceCombined approachrespiratory tract diseasesMilkMilk fatMicrobial enzymesCattlebusinessAgronomy and Crop ScienceFood ScienceBiotechnologyJournal of the science of food and agricultureREFERENCES
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Role of biological control agents and physical treatments in maintaining the quality of fresh and minimally-processed fruit and vegetables

2019

International audience; Fruit and vegetables are an important part of human diets and provide multiple health benefits. However, due to the short shelf-life of fresh and minimally-processed fruit and vegetables, significant losses occur throughout the food distribution chain. Shelf-life extension requires preserving both the quality and safety of food products. The quality of fruit and vegetables, either fresh or fresh-cut, depends on many factors and can be determined by analytical or sensory evaluation methods. Among the various technologies used to maintain the quality and increase shelf-life of fresh and minimally-processed fruit and vegetables, biological control is a promising approac…

030309 nutrition & dieteticsmedia_common.quotation_subject[SDV]Life Sciences [q-bio]Biological pest controlHealth benefitsBiologyIndustrial and Manufacturing Engineering03 medical and health sciences0404 agricultural biotechnologyFood distributionFood PreservationEvaluation methodsVegetablesmicrobiotaHumansQuality (business)media_common2. Zero hunger0303 health sciencesbusiness.industryfresh-cutfood and beveragesBiocontrol04 agricultural and veterinary sciencesGeneral MedicineBiopreservation040401 food scienceBiotechnologyBiological Control AgentsFood productsFruitPostharvestpost-harvest decaybusinesscompetitionFood Sciencebiopreservation
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Intermolecular oxidative dehydrogenative 3,3′-coupling of benzo[b]furans and benzo[b]thiophenes promoted by DDQ/H+: total synthesis of shandougenine B

2016

With an excess of a strong acid, 2,3-dichloro-5,6-dicyano-1,4-quinone (DDQ) is shown to promote metal-free intermolecular oxidative dehydrogenative (ODH) 3,3'-coupling of 2-aryl-benzo[b]furans and 2-aryl-benzo[b]thiophenes up to 92% yield as demonstrated with 9 substrates. Based on the analysis of oxidation potentials and molecular orbitals combined with EPR, NMR and UV-Vis observations, the studied reaction is initiated by a DDQ-substrate charge transfer complex and presumably proceeds via oxidation of the substrate into an electrophilic radical cation that further reacts with another molecule of a neutral substrate. The coupling reactivity can easily be predicted from the oxidation potent…

116 Chemical sciencesEFFICIENTfree radicalscoupling reactionsvapaat radikaalit010402 general chemistryPhotochemistry01 natural sciencesMedicinal chemistryCoupling reactionoxidative dehydrogenationC BOND FORMATIONSCHOLL REACTIONELECTRON-TRANSFERMolecular orbitalReactivity (chemistry)luonnonaineiden synteesiDIPHOSPHINE LIGANDSta116BASIS-SETSCATALYZED STEREOSELECTIVE REACTIONS010405 organic chemistryChemistryOrganic ChemistrykytkentäreaktiotSubstrate (chemistry)Total synthesishapettava dehydroganaatiolaskennallinen kemiaCharge-transfer complex0104 chemical sciencesRadical ionsynthesis of natural productsACIDElectrophileCATION-RADICALSHETEROCYCLESOrganic Chemistry Frontiers
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Screening individual ability to perform descriptive analysis of food products : basic statements and application to a camembert cheese descriptive pa…

1995

A battery of sensory tests is proposed to select potential descriptive panelists. This set of tests is flavor specific. Several abilities are examined: odor and taste recognition, odor memory, discrimination and descriptive capacities. A detailed example of such a battery to select a Camembert cheese descriptive panel is given. The objectives of each test are discussed. Stimuli are chosen to be consistent with the sensory properties which can be perceived in cheese. Score distributions demonstrate the discrimination among candidates for each test. Globally, results show the difficulty to find 20 panelists amongst about a hundred with good scores on each test. The panel leader has to choose …

2. Zero hungerCommunicationDescriptive statisticsbusiness.industry[SDV]Life Sciences [q-bio]05 social sciences04 agricultural and veterinary sciencesCamembert cheese040401 food science050105 experimental psychologySensory SystemsTest (assessment)[SDV] Life Sciences [q-bio]0404 agricultural biotechnologySensory testsFood productsStatistics0501 psychology and cognitive sciencesMISE AU POINTSet (psychology)PsychologybusinessComputingMilieux_MISCELLANEOUSFood Science
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