Search results for " profiles"
showing 10 items of 118 documents
Penalized linear discriminant analysis and Discrete AdaBoost to distinguish human hair metal profiles: The case of adolescents residing near Mt. Etna
2016
The research focus of the present paper was twofold. First, we tried to document that human intake of trace elements is influenced by geological factors of the place of residence. Second, we showed that the elemental composition of human hair is a useful screening tool for assessing people's exposure to potentially toxic substances. For this purpose, we used samples of human hair from adolescents and applied two robust statistical approaches. Samples from two distinct geological and environmental sites were collected: the first one was characterized by the presence of the active volcano Mt. Etna (ETNA group) and the second one lithologically made up of sedimentary rocks (SIC group). Chemica…
Levels of trace elements in human hair samples of adolescents living near petrochemical plants
2020
The aim of the study is a comparative analysis to investigate human hair metal profiles of adolescents residing near petrochemical plants (Sicily, Italy). We selected the small town of Augusta, Gela, and Pace del Mela, and a control area made up of the towns characterized by low anthropogenic activity. Twenty trace elements were measured in samples of scalp hair from adolescents (11–14 years old) of both genders. Hair samples were cleaned using a rigorous cleaning method, mineralized, and processed for analyses by inductively coupled plasma–mass spectrometry (ICP-MS). In industrial sites, zinc was always the most abundant element, ranging from186 to 217 μg g−1. Following zinc, the elements …
Frailty Status Typologies in Spanish Older Population: Associations with Successful Aging
2020
Background: Defining frailty typologies would contribute to guiding specific care interventions. These typologies could additionally be related to different health outcomes. This study aims at identifying subgroups of frail older adults based on the physical frailty phenotype and examining the relationships of these frailty profiles with quality of life and perceived health. Methods: This study relies on data from the SHARE project, namely a representative sample of 1765 Spanish-dwelling older adults identified as frail or pre-frail. Analysis included general descriptive statistics, exploratory latent class analysis (LCA) to determine the number of frailty subgroups, and LCA with covariates…
Cohort Profile: the EPI-CT study: a European pooled epidemiological study to quantify the risk of radiation-induced cancer from paediatric CT
2018
International audience; •The multinational EPI-CT study was set-up in 2011 to provide direct estimates of risk of solid tumours and leukaemia among children and young adults who underwent computed tomography (CT) scanning and to consolidate the scientific basis for optimization of paediatric CT protocols and patient protection.•Under a common protocol, cohort studies were conducted in Belgium, Denmark, France, Germany, the Netherlands, Norway, Spain, Sweden and the United Kingdom, coordinated by the International Agency for Research on Cancer (IARC). •The study recruited a total of about 950,000 patients having undergone at least one CT-scan before the age of 22 years. A total of 8.7 millio…
Perception of Dating Violence in Teenage Couples: A Cross Validation Study in Spain and Colombia
2020
Background: dating violence, or violence in teenage couples, is a socially interesting topic, due to its prevalence and its possible use in predicting violence in adult couples. The perception of violence, or the detection of abusive behaviors by teenagers and young people (which can be considered as equivalent concepts), is essential to prevent violence itself. Therefore, the main objective of this research is to determine which behaviors are identified as abusive by teenagers and young people, and the severity that they attribute to them&mdash
Health asset profiles and health indicators among 13- and 15-year-old adolescents
2018
Objectives We examined the associations between adolescents’ health assets and various health indicators (smoking, alcohol use, sleep length, physical activity, healthy eating, oral health, self-reported health, multiple health complaints). Methods A nationally representative sample was drawn from Finnish-speaking schools, comprising 13- and 15-year-old adolescents (n = 3833). The measures taken covered the adolescents’ health assets, which were labelled Family-financial, Psychological, Family-social, Friends-social, School-social, and Human. Our analysis applied two-step cluster analysis and multilevel mixed-effects binary logistic regression. Results Six asset profiles were identified: ‘L…
Structural performances of pultruded GFRP emergency structures – Part 1: Experimental characterization of materials and substructure
2019
Abstract This paper presents an experimental study in the field of structures made of pultruded fiber reinforced polymers (FRP) elements to be used for emergency purposes. A preliminary design of a 3D pultruded glass fiber reinforced polymer structure is presented with the mechanical characterization of the constituting elements. The axial and flexural properties of laminate and I-shaped GRFP profiles are discussed considering the short term creep. In a companion paper, the benefits, the limits and the reliability of the structure analyzed for emergency applications are discussed. In details, the numerical structural analysis of the full-scale 3D model is described followed by the experimen…
Unraveling the Reaction Mechanism of Enzymatic C5-Cytosine Methylation of DNA. A Combined Molecular Dynamics and QM/MM Study of Wild Type and Gln119 …
2016
M.HhaI is a DNA methyltransferase from Haemophilus hemolyticus that catalyzes the transfer of a methyl group from S-adenosyl-l-methionine (SAM) to the C5 position of a cytosine. This enzyme is a paradigmatic model for C5 DNA methyltransferases due to its major homology to mammalian enzymes and to the availability of high-resolution structures of the DNA–enzyme complex. In spite of the number of experimental and theoretical analyses carried out for this system, many mechanistic details remain unraveled. We have used full atomistic classical molecular dynamics simulations to explore the protein–SAM–DNA ternary complex, where the target cytosine base is flipped out into the active site for bot…
LA SCUOLA OFFICINA MECCANICA PRESSO IL VILLAGGIO MONTE DEGLI ULIVI A RIESI. RICOSTRUZIONE DI UN PROCESSO TRA ANALISI COMPOSITIVE E GRAFICO-GEOMETRICHE
2015
Il presente contributo trae origine da una più ampia ricerca che ha consentito di approfondire la comprensione dei principi progettuali e geometrico-compositivi dell’opera in oggetto; avvalendosi anche di un rilievo scientifico integrato che, attraverso nuove tecniche digitali applicate, ha permesso di condurre una specifica analisi grafico-geometrica sull’impianto architettonico1. L’edificio della scuola officina meccanica, inserito in un più ampio e articolato complesso edilizio2, è composto da una singolare configurazione in pianta ai diversi livelli, oggi non più chiaramente leggibile a causa dei numerosi interventi di trasformazione subiti. I disegni di restituzione grafica, realizzati…
MetAphAs Test. Metalanguage in Aphasia Assessment.
2018
Test MetAphAs: La evaluación del metalenguaje en la afasia (Rosell-Clari & Hernández-Sacristán, 2018) es una versión adaptada y abreviada de Rosell Clari & Hernández Sacristán, 2014). Esta prueba fue desarrollada inicialmente para evaluar las habilidades metalingüísticas naturales en personas con afasia (Hernández-Sacristán, Rosell-Clari, Serra-Alegre y Quiles-Climent, 2012). Las habilidades metalingüísticas naturales se refieren al uso del lenguaje que revela reflexividad (Hockett, 1960); es decir, la distancia perceptiva del hablante con respecto a su propio comportamiento verbal (Werner & Kaplan, 1978). Esta autoconciencia del lenguaje nos permite monitorear nuestros propios comportamien…