Search results for " project"

showing 10 items of 1296 documents

Periodontal treatment with an Er:YAG laser compared to ultrasonic instrumentation: a pilot study.

2004

The aim of the present study was to compare the effectiveness of an Er:YAG laser to that of ultrasonic scaling for non-surgical periodontal treatment.Twenty patients with moderate to advanced periodontal disease were randomly treated in a split-mouth design with a single episode of subgingival debridement using either an Er:YAG laser device (160 mJ/pulse, 10 Hz) combined with a calculus detection system with fluorescence induced by 655 nm InGaAsP diode laser radiation (ERL), or an ultrasonic instrument (UI). Clinical assessments of full-mouth plaque score (FMPS), bleeding on probing (BOP), probing depth (PD), gingival recession (GR), and clinical attachment level (CAL) were made at baseline…

AdultMalemedicine.medical_treatmentUltrasonic TherapyBleeding on probingDentistryPilot Projectslaw.inventionRoot PlaningRandomized controlled triallawmedicineHumansGingival RecessionGingival recessionPeriodontal DiseasesAnalysis of Variancebusiness.industryCalculus (dental)Dental Plaque IndexMiddle AgedLasermedicine.diseaseDental Plaque IndexTreatment OutcomeDebridement (dental)PeriodonticsDental ScalingFemaleLaser Therapymedicine.symptombusinessGingival HemorrhageEr:YAG laserJournal of periodontology
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Safety of etanercept therapy in rheumatoid patients undergoing surgery: preliminary report

2009

This is a preliminary report on a case-series of rheumatoid patients that underwent various kinds of elective surgery but did not withdraw etanercept therapy in spite of physician advise. Elective surgery consisted of right knee surgical prosthesis, bilateral cataract, bilateral hallux valgus, right hip prosthesis, bladder stone by cystoscopy and left inguinal hernia. All the patients had a regular healing rate. During follow-up (6-12 months) no one of these patients were suffering from infective complications after surgery. According to same recent literature results, our data suggest that it is the time to value rheumatoid patient preferences through a correct information about cost-benef…

AdultMalemusculoskeletal diseasesmedicine.medical_specialtySettore MED/09 - Medicina InternaPilot ProjectsReceptors Tumor Necrosis FactorEtanerceptEtanerceptArthritis RheumatoidPostoperative ComplicationsPatient satisfactionRheumatologyInternal medicinemedicineHumansPostoperative PeriodElective surgeryWound Healingmedicine.diagnostic_testTumor Necrosis Factor-alphabusiness.industryContraindicationsGeneral MedicineCystoscopyMiddle Agedmedicine.diseaseRheumatologySurgerySettore MED/16 - ReumatologiaTolerabilityElective Surgical ProceduresImmunoglobulin GRheumatoid arthritisFemaleBiological therapy Decompensated diabetes mellitus Etanercept Polymyalgia rheumatica Steroid therapy.businessAdverse drug reactionmedicine.drugClinical Rheumatology
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Training at maximal power in resisted sprinting: Optimal load determination methodology and pilot results in team sport athletes.

2018

Aims: In the current study we investigated the effects of resisted sprint training on sprinting performance and underlying mechanical parameters (force-velocity-power profile) based on two different training protocols: (i) loads that represented maximum power output (Lopt) and a 50% decrease in maximum unresisted sprinting velocity and (ii) lighter loads that represented a 10% decrease in maximum unresisted sprinting velocity, as drawn from previous research (L10). Methods: Soccer [n = 15 male] and rugby [n = 21; 9 male and 12 female] club-level athletes were individually assessed for horizontal force-velocity and load-velocity profiles using a battery of resisted sprints, sled or robotic r…

AdultMalevelocityhuman performancePhysiology[SDV]Life Sciences [q-bio]educationlcsh:MedicinePilot ProjectsAthletic PerformanceResearch and Analysis MethodsRemote SensingWeight-BearingMotionMathematical and Statistical TechniquesMedicine and Health SciencesrunningHumansStatistical Methodslcsh:ScienceroboticsBehaviorBiological LocomotionPhysicsMechanical Engineeringlcsh:RBiology and Life SciencesClassical MechanicsResistance TrainingaccelerationSports ScienceAthletesPhysical Scienceslinear regression analysisRecreationRegression AnalysisEngineering and TechnologyFemalelcsh:Qsportshuman activitiesMathematicsStatistics (Mathematics)Research ArticleradarPLoS ONE
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Enriched cereal bars are more effective in increasing plasma quercetin compared with quercetin from powder-filled hard capsules

2011

The flavonol quercetin, is one of the major flavonoids found in edible plants. The bioavailability of quercetin in humans may be influenced by the food matrix in which it is consumed as well as by its chemical and physical form. The objective of the present study was to investigate the biokinetics of quercetin from quercetin-enriched cereal bars and quercetin powder-filled hard capsules. In a randomised, single-blinded, diet-controlled cross-over study, six healthy women aged 22–28 years took a single oral dose of approximately 130 mg quercetin equivalents from either quercetin-enriched cereal bars (containing 93·3 % quercetin aglycone plus 6·7 % quercetin-4′-glucoside) or quercetin powder-…

AdultMedicine (miscellaneous)CapsulesPilot ProjectsDisaccharidesHigh-performance liquid chromatographyAntioxidantsSingle oral doseYoung Adultchemistry.chemical_compoundHumansIngestionSingle-Blind MethodFood scienceAntihypertensive AgentsIsorhamnetinCross-Over StudiesNutrition and DieteticsBioavailabilityKineticsTamarixetinAglyconechemistryBiochemistryDietary SupplementsFood FortifiedFast FoodsFemaleQuercetinPowdersEdible GrainQuercetinNutritive ValueBritish Journal of Nutrition
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The efficacy of N-acetylcysteine as a hepatoprotective agent in liver transplantation

1998

One of the most common complications after liver transplantation is primary graft dysfunction which results from severe deterioration of the microcirculation. The data obtained from our experimental studies indicate that N-acetylcysteine (NAC) is able to reduce the severity of ischemia/reperfusion injury and improves postoperative graft function after liver transplantation in rats. The aim of this pilot study was to evaluate the efficacy of NAC as a hepatoprotective agent under clinical conditions. A group of 30 liver transplanted patients were treated with NAC, and 30 patients (control group) were treated with a 5 % solution of glucose only. In the NAC group we observed a distinct reductio…

AdultNephrologymedicine.medical_specialtymedicine.medical_treatmentIschemiaPrimary Graft DysfunctionPilot ProjectsLiver transplantationGastroenterologyAcetylcysteineInternal medicineHumansMedicineProspective StudiesHepatoprotective AgentTransplantationbusiness.industryMiddle Agedmedicine.diseaseAcetylcysteineLiver TransplantationSurgeryReperfusion InjuryLiver functionbusinessReperfusion injurymedicine.drugTransplant International
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Outcome of peripheral blood stem cell mobilization in advanced phases of CML is dependent on the type of chemotherapy applied

1998

High-dose chemotherapy with autologous transplantation of in vivo purged PBSC is a novel investigational approach to treating chronic myelogenous leukemia (CML) patients not responsive to conventional therapy with interferon-alpha (IFN-alpha) and not eligible for allogeneic transplantation. PBSC mobilization using either '5+2/7+3'-type chemotherapy or 'mini-ICE/ ICE' chemotherapy was investigated in 43 patients with advanced phases of Philadelphia (Ph)-positive CML. Thirty patients were in late chronic phase (12 months post diagnosis) and 13 patients in accelerated phase (AP) or blast crisis (BC). Contamination with Ph-positive cells was evaluated in harvests from 37/43 patients. The outcom…

AdultOncologymedicine.medical_specialtyTime FactorsAllogeneic transplantationmedicine.medical_treatmentPilot ProjectsCarboplatinCohort StudiesLeukemia Myelogenous Chronic BCR-ABL PositiveInternal medicineAntineoplastic Combined Chemotherapy ProtocolsmedicineHumansAutologous transplantationIfosfamideEtoposideChemotherapyMobilizationHematologybusiness.industryHematologyGeneral MedicineLeukapheresisMiddle Agedmedicine.diseaseHematopoietic Stem Cell MobilizationSurgeryTreatment OutcomeBlast CrisisComplicationbusinessChronic myelogenous leukemiaAnnals of Hematology
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Non-invasive diagnosis in a case of bronchopulmonary sequestration and proposal of diagnostic algorhythm

2008

The case of a 43-year-old woman with intralobar pulmonary sequestration, Pryce type one, is presented. The medical history was characterised by recurrent bronchopneumonia, productive cough with purulent sputum and hemoptysis in the last three years. Diagnosis was made by CT angiography: multiplanar, maximum intensity projection and volume rendering reconstructions were visualised. A volume reduction of middle and lower lobe with multiple cyst-like bronchiectasis was detected and no evident relationship with tracheobronchial tree was pointed out. Reconstructions aimed at evaluating bronchial structures demonstrated no patency of middle and lower lobar bronchi. The study carried out after con…

AdultPulmonary and Respiratory Medicinemedicine.medical_specialtylcsh:MedicinePulmonary sequestrationmedicine.arterymedicineHumansThoracic aortaBronchopulmonary sequestrationBronchopulmonary sequestrationBronchiectasismedicine.diagnostic_testbusiness.industryDecision Treeslcsh:RLung imagingmedicine.diseaseContrast mediumCT angiographyMaximum intensity projectionAngiographyVascular DisorderFemaleRadiologyCardiology and Cardiovascular MedicinebusinessAlgorithmsMonaldi Archives for Chest Disease
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The randomized shortened dental arch study (RaSDA): design and protocol

2010

Abstract Background Various treatment options for the prosthetic treatment of jaws where all molars are lost are under discussion. Besides the placement of implants, two main treatment types can be distinguished: replacement of the missing molars with removable dental prostheses and non-replacement of the molars, i.e. preservation of the shortened dental arch. Evidence is lacking regarding the long-term outcome and the clinical performance of these approaches. High treatment costs and the long time required for the treatment impede respective clinical trials. Methods/design This 14-center randomized controlled investigator-initiated trial is ongoing. Last patient out will be in 2010. Patien…

AdultResearch designTime FactorsMedicine (miscellaneous)DentistryPilot ProjectsProsthesis Designlaw.inventionTooth LossDental ArchPatient satisfactionstomatognathic systemRandomized controlled trialQuality of lifelawGermanyStudy protocolTooth lossPremolarHumansMedicinePharmacology (medical)Orthodonticslcsh:R5-920business.industryJaw Edentulous PartiallyClinical trialDental ImplantationDental archTreatment Outcomemedicine.anatomical_structurePatient SatisfactionResearch DesignQuality of LifeDenture Partial FixedDenture Partial Removablemedicine.symptomlcsh:Medicine (General)businessTrials
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Blue-yellow deficiencies in young moderate smokers.

2021

Purpose To evaluate whether tobacco affects color vision in young moderate smokers. Methods Chromatic mechanisms of 13 moderate smokers (10–20 cigarettes/day and at least 5 years smoking) and 17 non-smokers in the 18–35 age range were assessed with the Farnsworth-Munsell 100-hue (FM100h) test and short wavelength automated perimetry (SWAP). Results FM100h Total Error Scores (TES) were higher for smokers, and although differences were not significant (p = 0.14), a linear model with principal component analysis was able to explain 95% of the variance in TES and red-green partial error scores, though not in blue-yellow partial error scores (p = 0.07), using the number of years as smokers and t…

AdultRetinal Ganglion Cellsmedicine.medical_specialtygenetic structuresAdolescentColor visionPilot ProjectsAudiologySensitivity lossRetinal ganglionTotal errorYoung smokers03 medical and health sciencesYoung Adult0302 clinical medicineShort wavelength automated perimetryMedicineHumansDifference mapSmokersColour visionbusiness.industryColour VisionBlue/yellow perimetry030221 ophthalmology & optometryLinear ModelsVisual Field TestsBlue-yellow perimetryOriginal Articlebusiness030217 neurology & neurosurgeryColor PerceptionOptometryJournal of optometry
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Dopamine receptor 2 activation inhibits ovarian vascular endothelial growth factor secretion in vitro: implications for treatment of ovarian hypersti…

2013

Objective To ascertain whether vascular endothelial growth factor (VEGF) secretion by luteinized granulosa cells (GCs) is modulated by the dopaminergic system in a dose-dependent fashion and how this is related to the differential efficacy of dopamine receptor 2 (D2)-agonists (D2-ag) in preventing ovarian hyperstimulation syndrome (OHSS). Design The relationship between the dopaminergic system and VEGF secretion in luteinized GCs was evaluated. Archived human ovaries were immunostained to characterize D2 expression. Setting University affiliated infertility center. Patient(s) Premenopausal women and egg donors. Intervention(s) Luteinized GCs were cultured with the D2-ag cabergoline. Human o…

AdultVascular Endothelial Growth Factor Aendocrine systemmedicine.medical_specialtyOvarian hyperstimulation syndromePilot ProjectsLuteal phaseBiologyOvarian Hyperstimulation Syndromechemistry.chemical_compoundCabergolineInternal medicinemedicineHumansSecretionCells CulturedGranulosa CellsReceptors Dopamine D2OvaryDopaminergicObstetrics and GynecologyMiddle Agedmedicine.diseaseVascular endothelial growth factorTreatment OutcomeEndocrinologyReproductive MedicinechemistryDopamine receptorDopamine AgonistsImmunohistochemistryFemalesense organsmedicine.drugFertility and Sterility
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