Search results for " quality of life."

showing 10 items of 343 documents

Preliminary experience with a transcranial magnetic resonance-guided focused ultrasound surgery system integrated with a 1.5-T MRI unit in a series o…

2018

OBJECTIVETranscranial magnetic resonance–guided focused ultrasound surgery (tcMRgFUS) is one of the emerging noninvasive technologies for the treatment of neurological disorders such as essential tremor (ET), idiopathic asymmetrical tremor-dominant Parkinson’s disease (PD), and neuropathic pain. In this clinical series the authors present the preliminary results achieved with the world’s first tcMRgFUS system integrated with a 1.5-T MRI unit.METHODSThe authors describe the results of tcMRgFUS in a sample of patients with ET and with PD who underwent the procedure during the period from January 2015 to September 2017. A monolateral ventralis intermedius nucleus (VIM) thalamic ablation was pe…

MaleParkinson's diseaseMovement disordershigh-intensity focused ultrasound ablationIntraoperative Neurophysiological Monitoringmedicine.medical_treatmentinterventional030218 nuclear medicine & medical imagingMagnetic resonance guided focused ultrasound surgery0302 clinical medicineThalamusEssential tremorSettore MED/27 - NeurochirurgiaUltrasoundSettore MED/37 - NeuroradiologiaParkinson DiseaseGeneral MedicineMiddle AgedAblationMagnetic Resonance ImagingTreatment OutcomeNeuropathic painBBB = blood-brain barrier; ET = essential tremor; FRFSE = fast recalled FSE; FSE = fast spin echo; FSPGR = fast spoiled gradient echo; FTM = Fahn-Tolosa-Marin; HI-FU = high-intensity focused ultrasound; MRI; MRgFUS; MS = multiple sclerosis; PD = Parkinson’s disease; Parkinson’s disease; QUEST = Quality of Life in Essential Tremor; SWAN = susceptibility-weighted angiography; UPDRS = Unified Parkinson’s Disease Rating Scale; VIM = ventralis intermedius nucleus; brain; essential tremor; high-intensity focused ultrasound ablation; interventional; magnetic resonance–guided focused ultrasound surgery; stereotactic technique; tcMRgFUS = transcranial magnetic resonance–guided focused ultrasound surgerySettore MED/26 - NeurologiaFemaleRadiologymedicine.symptombrain; essential tremor; high-intensity focused ultrasound ablation; interventional; magnetic resonance-guided focused ultrasound surgery; mrgfus; mri; parkinson's disease; stereotactic techniqueMRIAdultmedicine.medical_specialtybrainEssential Tremormagnetic resonance–guided focused ultrasound surgery03 medical and health sciencesmedicineHumansmagnetic resonance-guided focused ultrasound surgeryUltrasonography InterventionalAgedThalamotomybusiness.industryMRgFUSmedicine.diseasestereotactic techniqueparkinson's diseaseParkinson’s diseaseSurgeryNeurology (clinical)businessSettore MED/36 - Diagnostica Per Immagini E Radioterapia030217 neurology & neurosurgeryFollow-Up StudiesNeurosurgical focus
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Changes in magnetic resonance imaging disease measures over 3 years in mildly disabled patients with relapsing-remitting multiple sclerosis receiving…

2011

Abstract Background Conventional magnetic resonance imaging (MRI) has improved the diagnosis and monitoring of multiple sclerosis (MS). In clinical trials, MRI has been found to detect treatment effects with greater sensitivity than clinical measures; however, clinical and MRI outcomes tend to correlate poorly. Methods In this observational study, patients (n = 550; 18-50 years; relapsing-remitting MS [Expanded Disability Status Scale score ≤4.0]) receiving interferon (IFN) β-1a therapy (44 or 22 µg subcutaneously [sc] three times weekly [tiw]) underwent standardized MRI, neuropsychological and quality-of-life (QoL) assessments over 3 years. In this post hoc analysis, MRI outcomes and corre…

MalePathologyNeurologyDiseaseRelapsing-RemittingNeuropsychological Testslcsh:RC346-4290302 clinical medicineRelapsing-Remitting Multiple Sclerosi030212 general & internal medicine10. No inequalitymedicine.diagnostic_testBrainGeneral MedicineMagnetic Resonance Imaging3. Good healthFemaleSettore MED/26 - NeurologiaRadiologyNeurosurgeryMagnetic Resonance Imaging; Neuroimaging; Immunologic Factors; Dose-Response Relationship Drug; Humans; Brain; Interferon-beta; Quality of Life; Multiple Sclerosis Relapsing-Remitting; Cognition Disorders; Adult; Neuropsychological Tests; Female; MaleDrugInterferon beta-1aResearch ArticleAdultmedicine.medical_specialtyMultiple SclerosisClinical NeurologyNeuroimagingDose-Response Relationship03 medical and health sciencesMultiple Sclerosis Relapsing-RemittingNeuroimagingmedicineImmunologic FactorsHumansNeurochemistrylcsh:Neurology. Diseases of the nervous systemDose-Response Relationship Drugbusiness.industryMultiple sclerosisMagnetic resonance imagingBrain Magnetic Resonance ImagingInterferon-betamedicine.diseaseClinical trialBrain Magnetic Resonance Imaging; Relapsing-Remitting Multiple Sclerosis; Interferon beta-1aQuality of LifeNeurology (clinical)businessCognition Disorders030217 neurology & neurosurgery
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Definition of fibromyalgia severity: findings from a cross-sectional survey of 2339 Italian patients

2021

Abstract Objective To establish optimal cut-off values for the scores of the revised Fibromyalgia Impact Questionnaire (FIQR), the modified Fibromialgia Assessment Scale (FAS 2019mod), and the Polysymptomatic Distress Scale (PDS) in order to distinguish five levels of FM disease severity. Methods Consecutive FM patients were evaluated with the three clinimetric indices, and each patient was required to answer the anchor question: ‘In general, would you say your health is 1 = very good, 2 = good, 3 = fair, 4 = poor, or 5 = very poor?’—which represented the external criterion. Cut-off points were established through the interquartile reconciliation approach. Results The study sample consisted…

MalePercentileSettore MED/16 - REUMATOLOGIAFibromyalgiaCross-sectional studyseverityDiseaseSeverity of Illness IndexEconomica0302 clinical medicinemodifiedInterquartile rangeRetrospective StudieFibromyalgiaSurveys and QuestionnairesSurveys and QuestionnairePharmacology (medical)030212 general & internal medicinecut-off pointsPain MeasurementFibromyalgia Assessment Status; cut-off points; fibromyalgia; modified; polysymptomatic distress scale; revised Fibromyalgia Impact Questionnaire; severity; Cross-Sectional Studies; Female; Fibromyalgia; Follow-Up Studies; Humans; Incidence; Italy; Male; Middle Aged; Pain Measurement; Prognosis; Retrospective Studies; Severity of Illness Index; Surveys and Questionnaires; Quality of LifeIncidencerevised Fibromyalgia Impact Questionnairecut-off points; fibromyalgia; Fibromyalgia Assessment Status; modified; polysymptomatic distress scale; revised Fibromyalgia Impact Questionnaire; severityMiddle AgedPrognosisDistressItalyFemalefibromyalgiaFibromyalgia Assessment StatusHumanmedicine.medical_specialtyPrognosiRevised Fibromyalgia Impact QuestionnaireFollow-Up Studie03 medical and health sciencesRheumatologyInternal medicineSeverity of illnesscut-off pointmedicineHumansRetrospective Studies030203 arthritis & rheumatologyCross-Sectional Studiebusiness.industrymedicine.diseaseFibromyalgia Assessment StatuCross-Sectional StudiesFibromyalgia; severity; cut-off points; revised Fibromyalgia Impact Questionnaire; modified; Fibromyalgia Assessment Status; polysymptomatic distress scalepolysymptomatic distress scalefibromyalgia assessment status; cut-off points; fibromyalgia; modified; polysymptomatic distress scale; revised fibromyalgia impact questionnaire; severityQuality of LifebusinessFollow-Up Studies
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Oral health-related quality of life in complete denture wearers depending on their socio-demographic background, prosthetic-related factors and clini…

2012

Objectives: To investigate the differences in impact on oral health-related quality of life (OHRQoL) among complete denture wearers depending on their socio-demographic characteristics, prosthetic-related factors and oral status. Study Design: 51 patients aged 50-90 years treated, from 2005 to 2010, with at least one complete denture at the Department of Buccofacial Prostheses of the Complutense University (Madrid) were enrolled in this cross-sectional study. All of the participants answered the Oral Health Impact Profile (OHIP-14sp) questionnaire. The additive scoring method was used. The prevalence of impacts was calculated by using the occasional threshold (OHIP-14sp score≥2). Socio-demo…

MalePhysical disabilityCross-sectional studymedicine.medical_treatmentDentistryOral HealthOdontologíaPhysical examinationComplete dentureProsthesisPatient satisfactionQuality of lifeSickness Impact ProfileSurveys and QuestionnairesmedicineHumansOral Health Impact Profile (OHIP)General DentistryStomatitisAgedAged 80 and overOral Medicine and PathologyDenture Completemedicine.diagnostic_testbusiness.industryPatient satisfactionMiddle Aged:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseCiencias de la saludElderly patientsCross-Sectional StudiesSocioeconomic FactorsOtorhinolaryngologyOral health-related quality of life (OHRQoL)UNESCO::CIENCIAS MÉDICASQuality of LifeFemaleResearch-ArticleSurgeryDenturesbusinessMedicina Oral Patología Oral y Cirugia Bucal
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Oral health-related quality of life and clinical outcomes of immediately or delayed loaded implants in the rehabilitation of edentulous jaws: A retro…

2018

Background Patient-centered outcomes are being given great attention by the dental scientific community. The Oral Health Impact Profile -14 questionnaire (OHIP-14) has been introduced to address patients' success criteria when describing the impact of oral rehabilitations on quality of life (OHrQoL). Methods Thirty-five patients wearing a full-arch implant-prosthesis being in place between 4 and 6 years before this analysis were considered eligible and then enrolled in the present retrospective study. According to their prosthetic anamnesis, two groups were defined: delayed loading group (IL-group) and immediate loading group (IL-group). At the moment of analysis, clinical and radiographic …

MalePhysical disabilityTime FactorsDental prosthesismedicine.medical_treatmentOral Health030204 cardiovascular system & hematologyEdentulous/psychology/rehabilitation0302 clinical medicineQuality of lifeSurveys and QuestionnairesEndosseous/methods80 and overAnamnesisAged 80 and overRehabilitationDental prosthesisDental Implantation EndosseousMiddle Agedhumanitiesddc:617.6Dental ImplantationTreatment OutcomeRadiological weaponFemaleOral SurgeryEndosseousQuality of lifemedicine.medical_specialtyImmediate Dental Implant LoadingEdentulous03 medical and health sciencesDental ProsthesismedicineJaw EdentulousHumansAgedRetrospective StudiesDental Implantsbusiness.industryRetrospective cohort study030206 dentistryImplant-SupportedDental implants; Dental prosthesis; Implant-supported; Quality of life; Aged; Aged 80 and over; Dental Implantation Endosseous; Dental Implants; Dental Prosthesis Implant-Supported; Female; Humans; Immediate Dental Implant Loading; Jaw Edentulous; Male; Middle Aged; Patient Outcome Assessment; Retrospective Studies; Surveys and Questionnaires; Time Factors; Treatment Outcome; Oral Health; Quality of LifePatient Outcome Assessmentstomatognathic diseasesOtorhinolaryngologyJawPhysical therapyQuality of LifeSurgeryObservational studyDental Prosthesis Implant-Supportedbusiness
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HIDRAdisk: validation of an innovative visual tool to assess the burden of hidradenitis suppurativa

2019

Background: Hidradenitis suppurativa (HS) is a chronic, relapsing, inflammatory skin disease characterized by painful inflamed nodules, recurrent abscesses and fistulas located in apocrine gland–bearing body sites. The negative impact of HS on patient's quality of life (QoL) has been reported to be greater than other dermatologic conditions as psoriasis and atopic eczema, and its improvement is an important goal in disease management. Nowadays, there are no specific validated QoL instruments available for HS and generic dermatologic questionnaires are used. Objective: The objective of this study was to demonstrate the validity, reliability and responsiveness of HIDRAdisk, a new innovative t…

MalePsychometricsVisual Analog ScaleIntraclass correlationAcne ‐ RosaceaHIDRAdiskLongitudinal StudieSeverity of Illness Index030207 dermatology & venereal diseases0302 clinical medicineQuality of lifeSurveys and QuestionnairesHidradenitis suppurativa030212 general & internal medicineLongitudinal StudiesIMPACT IMPAIRMENT VALIDITY DISEASE.HIDRAdisk Hidradenitis Suppurativa Quality of Life Validation study Visual toolValidation studyDermatology Life Quality IndexMiddle AgedhumanitiesInfectious DiseasesHIDRAdisk; Hidradenitis Suppurativa; Quality of Life; Validation study; Visual toolItalyhidradenitis suppurativa; visual analog scale; quality of LifeFemaleOriginal ArticleSettore MED/35 - MALATTIE CUTANEE E VENEREEVisual toolPsychometricHumanAdultmedicine.medical_specialtyPsychometricsVisual analogue scaleReproducibility of ResultDermatology03 medical and health sciencesYoung AdultCronbach's alphaInternal medicineSeverity of illnessmedicineHumansbusiness.industryhidradenitis suppurativaReproducibility of Resultsmedicine.diseaseQuality of Lifebusiness
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Correlates of mortality in elderly COPD patients: focus on health-related quality of life

2009

BACKGROUND AND OBJECTIVE: The Saint George Respiratory Questionnaire (SGRQ) is widely used as a measure of health-related quality of life (HRQL) in patients with COPD. This study tested whether the SGRQ predicts the survival of patients with COPD. METHODS: The study recruited 238 patients with COPD who were participants in the multicentre Salute Respiratoria nell'Anziano (Sa.R.A.) study. Patients' sociodemographic, clinical and functional characteristics were assessed and the association between the SGRQ and mortality, corrected for potential confounders, was estimated. RESULTS: The mean age of study participants was 72.6 years. Over the 5-year observation period there were 88 deaths. After…

MalePulmonary and Respiratory MedicinePediatricsmedicine.medical_specialtyCopd patientsSettore MED/10 - Malattie Dell'Apparato RespiratorioRisk AssessmentSeverity of Illness IndexPulmonary Disease Chronic ObstructiveQuality of lifePredictive Value of TestsSurveys and QuestionnairesHumansMedicineAgedProportional Hazards ModelsHealth related quality of lifeCOPDbusiness.industryHazard ratioConfoundingPrognosismedicine.diseaseHealth SurveysCOPD mortality health-related quality of life.Confidence intervalItalyQuality of LifeFemalebusinessLower mortality
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Targeting quality of life in asthmatic children: The MyTEP pilot randomized trial

2019

Abstract Background Quality of life (QoL) is an important outcome in the management of children with asthma. Mobile Health (m-Health) and Therapeutic Education Programs (TEPs) are increasingly recognized as essential components of pediatric asthma management to improve disease outcomes. Objective To evaluate the effect of an education program (MyTherapeutic Education Program, MyTEP) that couples multidisciplinary TEP intervention with an m-Health Program (mHP) in improving QoL in asthmatic children. Methods This single-center study employed a nonblinded randomized clinical trial design. Italian-speaking children (6–11 years) with mild-moderate asthma were eligible for participation. Partici…

MalePulmonary and Respiratory Medicinemedicine.medical_specialtyTherapeutic educationlaw.invention03 medical and health sciences0302 clinical medicinePatient Education as TopicQuality of lifeRandomized controlled trialRisk FactorsAsthma Children Quality of life Therapeutic education Mobile healthlawSurveys and QuestionnairesmedicineHumansMobile health030212 general & internal medicineChildChildrenAsthma Children Quality of life Therapeutic education Mobile healthAsthmaDescriptive statisticsbusiness.industrySmall sampleTherapeutic educationmedicine.diseaseAsthmaTelemedicineAsthmatic childrenItaly030228 respiratory systemSpirometrySmartphone appQuality of LifePhysical therapyFemalebusinessFollow-Up StudiesRespiratory Medicine
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Design of a randomized controlled trial of physical training and cancer ( Phys-Can) the impact of exercise intensity on cancer related fatigue, quali…

2017

Background: Cancer-related fatigue is a common problem in persons with cancer, influencing health-related quality of life and causing a considerable challenge to society. Current evidence supports the beneficial effects of physical exercise in reducing fatigue, but the results across studies are not consistent, especially in terms of exercise intensity. It is also unclear whether use of behaviour change techniques can further increase exercise adherence and maintain physical activity behaviour. This study will investigate whether exercise intensity affects fatigue and health related quality of life in persons undergoing adjuvant cancer treatment. In addition, to examine effects of exercise …

MaleQuality of lifeCancer Researchmedicine.medical_specialtyActivities of daily livingBreast NeoplasmsPhysical exerciselcsh:RC254-282law.inventionStudy Protocol03 medical and health sciences0302 clinical medicinePhysical medicine and rehabilitationQuality of life (healthcare)Cancer SurvivorsRandomized controlled trialEndurance traininglawBehaviour change techniquesGeneticsmedicineHumans030212 general & internal medicineCancer-related fatigueFatigueCancerCancer och onkologibusiness.industryCancer; Physical exercise; Behaviour change techniques; Fatigue; Biological mechanism; Quality of life; Randomized controlled trialProstatic NeoplasmsPhysical exerciseBiological mechanismlcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogensExercise TherapyMoodOncologyPhysical FitnessRandomized controlled trial030220 oncology & carcinogenesisCancer and OncologyExercise intensityPhysical therapyFemalemedicine.symptomColorectal Neoplasmsbusiness
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Seasons and Other Factors Affecting the Quality of Life of Asthmatic Children

2007

Amparo.Escribano@uv.es Objective: To study the effect of seasons on the health-related quality of life (HRQL) of asthmatic children. Methods: Four groups of asthmatic children 7 to 14 years old were recruited by pediatricians during each season of the year. Their HRQL was assessed by means of the Paediatric Asthma Quality of Life Questionnaire (PAQLQ). Other factors surveyed were asthma severity, atopy, medical treatment, immunotherapy, obesity, parental smoking, and anti-allergic measures. Results: The mean (SD) overall PAQLQ score was highest in summer at 6.2 (1.0) and lowest in autumn at 5.5 (1.2). The same trend was found for domains in summer and autumn, respectively: symptoms, 6.2 (1.…

MaleQuality of lifeOutpatient Clinics HospitalHealth StatusAsthma; Children; Immunotherapy; Quality of life; Seasons.Severity of Illness IndexAsthmaSeasons.Sex FactorsResidence CharacteristicsSpainPhysiciansUNESCO::CIENCIAS MÉDICAS ::Patología::HistopatologíaQuality of LifeHumansFemaleSeasonsImmunotherapyChildChildren:CIENCIAS MÉDICAS ::Patología::Histopatología [UNESCO]
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