Search results for " real life"

How Effective and Safe Is Bronchial Thermoplasty in “Real Life” Asthmatics Compared to Those Enrolled in Randomized Clinical Trials?

2016

There is limited information on the efficacy and safety of bronchial thermoplasty (BT) inreal life. We evaluated the outcomes of the randomized clinical trials for BT in severe asthmatics, in whom the exclusion criteria were not strictly controlled. A case series of seven asthmatics (M/F: 4/3; age:54.6±2.9years) is reported. Subjects had a statistically significant improvement in AQLQ (from a mean of3.96±1.1to4.5±1.2and5.5±0.6after 6 and 12 months of treatment;p=0.0007) and in the ACQ score (from2.77±0.8to1.83±1.2and1.5±0.8after 6 and 12 months;p<0.001). In the year after BT, severe exacerbations, salbutamol use, and OCS use were significantly lower compared with the 1-yr pretreatment pe…

Air quality indices: a review

2010

National directives on air quality oblige nations to monitor and report on their air quality, allowing the public to be informed on the ambient pollution levels. The last is the reason for the always increasing interest, demonstrated by the number of publications on this topic in recent years, in air quality/pollution indices: since the concentration of individual pollutants can be confusing, concentration measurements are conveniently transformed in terms of an air quality index. In this way, complex situations are summarized in a single figure, letting comparisons in time and space be possible. In this paper we will give an overview about the Air Quality/Pollution Indices proposed in lite…

¡Qué quejicosos! Buzón de quejas a través del aprendizaje cooperativo

2017

Resumen: En este artículo se ofrece una experiencia práctica enmarcada dentro del aprendizaje cooperativo, que crea una interdependencia positiva propicia para el aprendizaje. Para ello, después de una breve aproximación teórica al aprendizaje cooperativo, la argumentación y los actos de habla de queja, así como del género textual «carta de reclamación», se expone la propuesta de nivel B2 organizada en diferentes pasos: la selección de equipos, el análisis de cartas de reclamación, la modificación de los equipos, la asignación de roles, así como la escritura de cartas y posterior evaluación. Se trabajan distintas destrezas, además de conseguir que los alumnos interactúen como en la vida rea…

Egoistic and moralistic bias in real-life inventory responses

2008

Response-faking tendencies can be divided into moralistic and egoistic bias according to the contents of the issue faked (Paulhus & John, 1998). Our hypothesis was that in a work-related selection context faking would occur on the egoistic sub-scales, as these are related to competence and talent, which are issues relevant in selection. To minimize the amount of conscious faking, half of 466 real-life applicants were warned about the presence of a socially desirable responding sub-scale in the Personality Research Form (PRF). Half of the respondents (control group) received standard instructions. Of all the PRF sub-scales, only the ones measuring either egoistic or moralistic traits were st…

Randomized Controlled Trials and real life studies. Approaches and methodologies: a clinical point of view.

2014

Randomized Controlled Trials (RCTs) are the "gold standard" for evaluating treatment outcomes providing information on treatments "efficacy". They are designed to test a therapeutic hypothesis under optimal setting in the absence of confounding factors. For this reason they have high internal validity. The strict and controlled conditions in which they are conducted, leads to low generalizability because they are performed in conditions very different from real life usual care. Conversely, real life studies inform on the "effectiveness" of a treatment, that is, the measure of the extent to which an intervention does what is intended to do in routine circumstances. At variance to RCTs, real …

Erratum to “Inhaler mishandling remains common in real life and is associated with reduced disease control” [Respir Med 105 (6) 2011 930–938]

2012

Fixed Points for Multivalued Weighted Mean Contractions in a Symmetric Generalized Metric Space

2020

This paper defines two new concepts: the concept of multivalued left-weighted mean contractions in the generalized sense of Nadler in a symmetric generalized metric space and the concept of multivalued right-weighted mean contractions in the generalized sense of Nadler in a symmetric generalized metric space, and demonstrates fixed-point theorems for them. For these, we demonstrated two fixed-point existence theorems and their corollaries, by using the properties of the regular-global-inf function and the properties of symmetric generalized metric spaces, respectively. Moreover, we demonstrated that the theorems can be applied in particular cases of inclusion systems. This article contains …

Acceptability of partially dealcoholized wines - Measuring the impact of sensory and information cues on overall liking in real-life settings

2009

International audience; In this study, the effect of partial alcohol reduction in wine on consumer expectation and overall liking was investigated in real-life settings (by a Home-Use-Test). By varying the wine in the bottle and by manipulating the information on the label, it was possible to assess the relative impact of sensory properties and information cues on overall liking. Standard Chardonnay and Syrah wines were partially dealcoholized from about 13.5% to about 9.5%. After bottling, these dealcoholized wines were presented once with information about real alcohol content (9.5%) and once with false information about alcohol content (13.5%). A third bottle with standard wine inside wa…

Erenumab and Possible CGRP Effect on Chronotype in Chronic Migraine: A Real-Life Study of 12 Months Treatment

2023

The introduction of monoclonal antibodies (mAbs) directed against the calcitonin gene-related peptide (CGRP), or its receptor (CGRPr), revolutionized migraine management due to their high efficacy and few side effects. Data suggest that the CGRP may even be implicated in circadian rhythm, but studies about the effect of anti-CGRP treatments on sleep are still lacking. The aim of the present study was to assess the effect of erenumab (70 and 140 mg per month), a human mAb directed against CGRPr, on chronotype in chronic migraineurs; secondly, we assessed its efficacy, safety, and the effects on anxiety and depression. Sleep was evaluated using self-administrable questionnaires investigating …

How Wild Can It Get? Managing Language Learning Tasks in Real Life Service Encounters

2019

This chapter explores how experientially based pedagogical activities that involve participation in real life service encounters provide occasions for developing L2 interactional competence. The data comprises novice L2 students’ self-recorded interactions in service settings and videorecordings of classroom planning activities and de-briefing discussions, where the students reflect on their experiences. The analysis traces what kinds of occasions for learning arise as the students move between the classroom and the real-world service settings. The findings show that the different phases of the task complement each other in supporting the development of interactional competence. The prepara…