Search results for " regulation."

Enterobacter cloacae administration induces hepatic damage and subcutaneous fat accumulation in high-fat diet fed mice.

2018

Accumulating evidence indicates that gut microbiota plays a significant role in obesity, insulin resistance and associated liver disorders. Family Enterobacteriaceae and especially Enterobacter cloacae strain B29 have been previously linked to obesity and hepatic damage. The underlying mechanisms, however, remain unclear. Therefore, we comprehensively examined the effects of E. cloacae subsp. cloacae (ATCC® 13047™) administration on host metabolism of mice fed with high-fat diet (HFD). C57BL/6N mice were randomly divided into HFD control, chow control, and E. cloacae treatment groups. The E. cloacae treatment group received live bacterial cells in PBS intragastrically twice a week, every ot…

Affect self-regulation through music

2018

The present dissertation focused on musical affect regulation, i.e. on the use of music to self-regulate affective states such as emotions, moods, and energy levels. In publication I, relevant findings from previous research were extracted and the field’s conceptual clarity and precision was assessed. Besides identifying weaknesses in conceptualization and providing recommendations for future studies, publication I found that not all the elements of affect regulation through music have been equally explored by research. Given the gap observed on the study of musical mechanisms underlying affect regulation, publication II placed a special focus on this component and its association with regu…

Il distacco e la separazione emotiva nel rapporto tra genitori e figli adolescenti

2012

Differential associations of leisure music engagement with resilience : A network analysis

2023

Background/Objective Several factors associated with resilience as the maintenance of mental health despite stress exposure can be strengthened through participation in leisure time activities. Since many people listen to or make music in their leisure time, the aim of the present study was to provide insights into the architecture of how resilience relates to passive and active music engagement. Method 511 participants regularly listening to and/or making music completed an online survey on resilient outcomes (i.e., mental health and stressor recovery ability), different resilience factors (e.g., optimism, social support), quantitative music engagement (i.e., time spent with music listenin…

Inhibition of small G proteins of the Rho family by statins orClostridium difficiletoxin B enhances cytokine-mediated induction of NO synthase II

2000

In order to investigate the involvement of Ras and/or Rho proteins in the induction of the inducible isoform of nitric oxide synthase (NOS II) we used HMG-CoA reductase inhibitors (statins) and Clostridium difficile toxin B (TcdB) as pharmacological tools. Statins indirectly inhibit small G proteins by preventing their essential farnesylation (Ras) and/or geranylgeranylation (Rho). In contrast, TcdB is a glucosyltransferase and inactivates Rho-proteins directly. Human A549/8- and DLD-1 cells as well as murine 3T3 fibroblasts were preincubated for 18 h with statins (1–100 μM) or TcdB (0.01–10 ng ml−1). Then NOS II expression was induced by cytokines. NOS II mRNA was measured after 4–8 h by R…

Lotic life stages of the European river lamprey (Lampetra fluviatilis) : anthropogenic detriment and rehabilitation

2015

Diseño de un sistema de apoyo a la regulación social del aprendizaje en los xMOOC

2019

Esta investigación tiene como objetivo estudiar los procesos de regulación del aprendizaje, atendiendo tanto a su dimensión individual como social, en entornos de xMOOC. En concreto, se propone analizar cómo los procesos de autorregulación, corregulación y regulación social compartida pueden apoyarse y promoverse en este tipo de contextos abiertos y masivos para conseguir un aprendizaje más profundo. Para ello, se aplica un modelo de investigación basada en el diseño que permite intervenir directamente en la práctica pedagógica, a través de un proceso cíclico de cuatro etapas: diseño, intervención, evaluación y reflexión y rediseño de un sistema de apoyo a la regulación del aprendizaje en u…

Emotional self-regulation through music in 3-8-year-old children

2009

The current study explored the role of music in children’s emotional self-regulation. Music is shown to be a common and effective way of self-regulating emotions in adolescence and adulthood. It is also widely known that parents use music to regulate the emotions of their babies, for instance in calming them down by lullabies. However, very little is known about how children themselves use music for emotional needs, and how the self-regulatory emotional engagement develops. A survey study was conducted with parents of 63 children including 37 boys and 26 girls, aged between 2.9 to 8.1 years. The parents answered questions about their child’s musical activities, preferences, and emotion-regu…

Strategies and mechanisms in musical affect self-regulation: A new model

2017

This study aimed at investigating the associations between regulation strategies and musical mechanisms involved in musical affect self-regulation. A sample of 571 participants was collected and the data regarding the reported strategies and mechanisms were analysed using correspondence analysis (CA). Three bipolar dimensions – cognition, feelings, and body – were retained for interpretation, thus revealing six contrasting strategic uses of music: cognitive work, entertainment, affective work, distraction, revival, and focus on situation. Clear associations between strategies and mechanisms emerged from the CA, connecting cognitive, feelings-focused, and situational processing with individ…

Bcl-xL as a Modulator of Senescence and Aging

2021

Many features of aging result from the incapacity of cells to adapt to stress conditions. When cells are overwhelmed by stress, they can undergo senescence to avoid unrestricted growth of damaged cells. Recent findings have proven that cellular senescence is more than that. A specific grade of senescence promotes embryo development, tissue remodeling and wound healing. However, constant stresses and a weakening immune system can lead to senescence chronicity with aging. The accumulation of senescent cells is directly related to tissue dysfunction and age-related pathologies. Centenarians, the most aged individuals, should accumulate senescent cells and suffer from their deleterious effects,…