Search results for " rese"
showing 10 items of 14841 documents
Relación del margen de resección con la supervivencia global y supervivencia libre de enfermedad de los pacientes afectos de metástasis hepáticas de …
2015
Actualmente, la resección hepática junto con la quimioterapia representa el único tratamiento curativo para las metástasis hepáticas de carcinoma colorrectal (MHCCR), con unas tasas de supervivencia a 5 años de hasta el 58%.1 Los últimos avances en supervivencia se deben a múltiples factores.2 Por una parte, a las nuevas estrategias quirúrgicas (embolización portal preoperatoria, hepatectomía en dos tiempos, etc); así como a la mejor selección de pacientes candidatos a cirugía en base a las nuevas definiciones de resecabilidad.3-5 Y por supuesto, al desarrollo de una quimioterapia más efectiva y de nuevos agentes biológicos para el tratamiento de los pacientes con MHCCR.6-10 El papel del ma…
Shedding Light on Early Stage Academic Entrepreneurship : Finnish University Researchers' View on Key Stakeholder Relations and Their Influence on th…
2020
Since the mid-1980s, along with the opening up of the Finnish economy, the pressure to commercialize university research has steadily increased in Finland. This is in line with the growing importance of innovations in an ever-globalizing world in which purely production- cost-based strategies are about to become obsolete. However, in comparison to other Nordic countries and Western European industrial countries, Finnish investments in research have fallen short in their ability to increase high-technology export levels (Kotiranta and Tahvanainen 2018). Moreover, Finnish academia faces challenges in creating university-based economic activity (Nikulainen and Tahvanainen 2013). In order to he…
The Hexameric Resorcinarene Capsule as a Brønsted Acid Catalyst for the Synthesis of Bis(heteroaryl)methanes in a Nanoconfined Space
2019
Herein, we show that the hexameric resorcinarene capsule C is able to catalyze the formation of bis(heteroaryl)methanes by reaction between pyrroles or indoles and carbonyl compounds (α-ketoesters or aldehydes) in excellent yields and selectivity. Our results suggest that the capsule can play a double catalytic role as a H-bond catalyst, for the initial activation of the carbonyl substrate, and as a Bronsted acid catalyst, for the dehydration of the intermediate alcohol.
Ecology Approach in Education and Health Care
2017
Abstract In the 21st century, numerous complex challenges in education and health care have come to the fore, among them: 1) how to implement the ecological approach in the education process and health care practice; 2) how to implement study programmes in line with the education trends for sustainable development and the process of formation and development of the ecological competence. The results of this research refer only to the content analysis of the essays written by the first and second year students of the programs in Nursing and Medicine on completing the study course The Ecological Approach in Patient Care. To increase the credibility and validity of the obtained results of the …
Behavioral Inhibition Underlies the Link Between Interoceptive Sensitivity and Anxiety-Related Temperamental Traits
2017
Interoceptive sensitivity is a biologically determined, constitutional trait of an individual. High interoceptive sensitivity has been often associated with proneness to anxiety. This association has been explained by elevated autonomic responsiveness in anxious individuals. However, in a heartbeat discrimination task (discrimination of heartbeats’ simultaneity to an external stimulus) low cardiac responsiveness has accompanied enhanced performance. The relation between these factors seems task dependent, and cannot comprehensively explain the link between interoceptive sensitivity and anxiety. We explored for additional explanatory factors for this link. More specifically, we studied which…
The Lotus japonicus ROP3 Is Involved in the Establishment of the Nitrogen-Fixing Symbiosis but Not of the Arbuscular Mycorrhizal Symbiosis
2021
Legumes form root mutualistic symbioses with some soil microbes promoting their growth, rhizobia, and arbuscular mycorrhizal fungi (AMF). A conserved set of plant proteins rules the transduction of symbiotic signals from rhizobia and AMF in a so-called common symbiotic signaling pathway (CSSP). Despite considerable efforts and advances over the past 20 years, there are still key elements to be discovered about the establishment of these root symbioses. Rhizobia and AMF root colonization are possible after a deep cell reorganization. In the interaction between the model legume Lotus japonicus and Mesorhizobium loti, this reorganization has been shown to be dependent on a SCAR/Wave-like signa…
Remembering an Era: Roger Penrose’s Paper on “Gravitational Collapse: The Role of General Relativity”
2018
Back in the 1960s, Einstein’s theory of general relativity re-emerged as a field of important research activity. Much of the impetus behind this resurgence came from powerful new mathematical ideas that Roger Penrose and Stephen Hawking applied to prove general singularity theorems for global space-time structures. Their results stirred the imaginations of astrophysicists and gave relativistic cosmology an entirely new research agenda. A decade later, black holes and the big hang model were on the tongues of nearly everyone who followed recent trends in science. As popular expositions dealing with quasars, pulsars, and the geometry of black holes began to appear in magazines and textbooks, …
Introduction: The Pedagogical Obstacle of the Phenomenal Forms
2016
This book is a further development from a previous one, published only in Spanish, whose title can be translated as The Copernican turn and the social sciences (Villacanas de Castro, 2013). It was a philosophical work relating to a general epistemological problem lying at the heart of the social and natural sciences. On the other hand, the present volume is firmly rooted in pedagogy. This difference reflects the professional journey that I have made in the meantime, from being a Graduate Student at a Faculty of Philosophy to becoming a member of staff at a Faculty of Education, where I currently lecture and carry out research. Despite the various shifts brought about by this transition, an …
The added value of studying embodied responses in couple therapy research : A case study
2019
This article reports on the added value of embodied responses identified through sympathetic nervous system (SNS) activity in couple therapy research. It focuses on moments of change and the timing of therapeutic interventions or therapeutic moves in a couple therapy session. The data for this single‐case study comprise couple therapy process videotapes recorded in a multi‐camera setting, and measurements of participants’ SNS activity. The voluntary participants were a marital couple in their late thirties and two middle‐aged male psychotherapists. The division into topic segments showed how the key issue of seeking help, which was found to comprise three separate components, was repeatedly…
Positive Computing as Paradigm to Overcome Barriers to Global Co-authoring of Open Educational Resources
2018
The adoption of Open Educational Resources (OER) can support collaboration and knowledge sharing. One of the main areas of the usage OER is the internationalization, i.e., the use in a global context. However, the globally distributed co-creation of digital materials is still low. Therefore, we identify essential barriers, in particular for co-authoring of OER in global environments. We use a design science research method to introduce a barrier framework for co-authoring OER in global settings and propose a wellbeing-based system design constructed from the barrier framework for OER co-authoring tool. We describe how positive computing concepts can be used to overcome barriers, emphasizing…