Search results for " research"
showing 10 items of 14115 documents
Introduction: The Pedagogical Obstacle of the Phenomenal Forms
2016
This book is a further development from a previous one, published only in Spanish, whose title can be translated as The Copernican turn and the social sciences (Villacanas de Castro, 2013). It was a philosophical work relating to a general epistemological problem lying at the heart of the social and natural sciences. On the other hand, the present volume is firmly rooted in pedagogy. This difference reflects the professional journey that I have made in the meantime, from being a Graduate Student at a Faculty of Philosophy to becoming a member of staff at a Faculty of Education, where I currently lecture and carry out research. Despite the various shifts brought about by this transition, an …
The added value of studying embodied responses in couple therapy research : A case study
2019
This article reports on the added value of embodied responses identified through sympathetic nervous system (SNS) activity in couple therapy research. It focuses on moments of change and the timing of therapeutic interventions or therapeutic moves in a couple therapy session. The data for this single‐case study comprise couple therapy process videotapes recorded in a multi‐camera setting, and measurements of participants’ SNS activity. The voluntary participants were a marital couple in their late thirties and two middle‐aged male psychotherapists. The division into topic segments showed how the key issue of seeking help, which was found to comprise three separate components, was repeatedly…
Positive Computing as Paradigm to Overcome Barriers to Global Co-authoring of Open Educational Resources
2018
The adoption of Open Educational Resources (OER) can support collaboration and knowledge sharing. One of the main areas of the usage OER is the internationalization, i.e., the use in a global context. However, the globally distributed co-creation of digital materials is still low. Therefore, we identify essential barriers, in particular for co-authoring of OER in global environments. We use a design science research method to introduce a barrier framework for co-authoring OER in global settings and propose a wellbeing-based system design constructed from the barrier framework for OER co-authoring tool. We describe how positive computing concepts can be used to overcome barriers, emphasizing…
'REOFUT' as an Observation Tool for Tactical Analysis on Offensive Performance in Soccer: Mixed Method Perspective
2019
Performance analysis in complex sports like soccer requires the study of the influence of the interaction between both teams during the game on final performance. The mixed methods approach involves the collection, analysis, and interpretation of qualitative and quantitative data for the same purpose and within the framework of the same study. To build certain observation tools, mixed methods are necessary in order to take advantage of integration between qualitative and quantitative elements. The aim of this study was to develop a new no standard observation tool to analyze soccer offensive performance considering not only the observed team but also some aspects of the opponent behavior, a…
Six-Week Endurance Exercise Alters Gut Metagenome That Is not Reflected in Systemic Metabolism in Over-weight Women.
2018
Recent studies suggest that exercise alters the gut microbiome. We determined whether six-weeks endurance exercise, without changing diet, affected the gut metagenome and systemic metabolites of overweight women. Previously sedentary overweight women (n = 19) underwent a six-weeks endurance exercise intervention, but two were excluded due to antibiotic therapy. The gut microbiota composition and functions were analyzed by 16S rRNA gene amplicon sequencing and metagenomics. Body composition was analyzed with DXA X-ray densitometer and serum metabolomics with NMR metabolomics. Total energy and energy-yielding nutrient intakes were analyzed from food records using Micro-Nutrica software. Serum…
Contributions of mean and shape of blood pressure distribution to worldwide trends and variations in raised blood pressure: A pooled analysis of 1018…
2018
Background: Change in the prevalence of raised blood pressure could be due to both shifts in the entire distribution of blood pressure (representing the combined effects of public health interventions and secular trends) and changes in its high-blood-pressure tail (representing successful clinical interventions to control blood pressure in the hypertensive population). Our aim was to quantify the contributions of these two phenomena to the worldwide trends in the prevalence of raised blood pressure. Methods: We pooled 1018 population-based studies with blood pressure measurements on 88.6 million participants from 1985 to 2016. We first calculated mean systolic blood pressure (SBP), mean dia…
Strategic Design Towards Platform Collaboration in The Newspaper Industry: A Design Science Research Study
2020
The newspaper industry is challenged by unsustainable business models. To stabilize dwindling revenue streams, publishers opted for digital subscriptions as one avenue for generating additional revenue streams. Large publishers have indeed benefited from rising subscription numbers. However, smaller publishers are challenged to achieve the same results. Some of the root causes are high churn rates, adoption costs and lock-in effects of subscription services. News aggregator platforms may promise newspaper publishers a large pool of paying readers. But platform fees and the loss of direct customer relationships enact commercial barriers among publishers. This study proposes design science re…
Dexamethasone premedication suppresses vaccine-induced immune responses against cancer
2020
ABSTRACT Glucocorticosteroids (GCS) have an established role in oncology and are administered to cancer patients in routine clinical care and in drug development trials as co-medication. Given their strong immune-suppressive activity, GCS may interfere with immune-oncology drugs. We are developing a therapeutic cancer vaccine, which is based on a liposomal formulation of tumor-antigen encoding RNA (RNA-LPX) and induces a strong T-cell response both in mice as well as in humans. In this study, we investigated in vivo in mice and in human PBMCs the effect of the commonly used long-acting GCS Dexamethasone (Dexa) on the efficacy of this vaccine format, with a particular focus on antigen-specif…
Transcranial Alternating Current Stimulation (tACS) Does Not Affect Sports People’s Explosive Power: A Pilot Study
2021
Purpose: This study is aimed to preliminary investigate whether transcranial alternating current stimulation (tACS) could affect explosive power considering genetic background in sport subjects.Methods: Seventeen healthy sports volunteers with at least 3 years of sports activities participated in the experiment. After 2 weeks of familiarization performed without any stimulation, each participant received either 50 Hz-tACS or sham-tACS. Before and after stimulation, subjects performed the following tests: (1) the squat jump with the hands on the hips (SJ); (2) countermovement jump with the hands on the hips (CMJ); (3) countermovement jump with arm swing (CMJ-AS); (4) 15-s Bosco’s test; (5) s…
Simultaneous optimization of harvest schedule and measurement strategy
2013
In many recent studies, the value of forest inventory information in the harvest scheduling has been examined. Usually only the profitability of measuring simultaneously all the stands in the area is examined. Yet, it may be more profitable to concentrate the measurement efforts to some subset of them. In this paper, the authors demonstrate that stochastic optimization can be used for defining the optimal measurement strategy simultaneously with the harvest decisions. The results show that without end-inventory constraints, it was most profitable to measure the stands that were just below the medium age. Measuring the oldest stands was not profitable at all. It turned out to be profitable t…