Search results for " response"
showing 10 items of 2127 documents
Linezolid in bolus vs linezolid in continous infusion. The host response in patients with severe sepsis.
2005
INTRODUCTION AND AIMS: Severe sepsis by gram positive pathogens is commonly associated with high morbidity and mortalità in every ICU. During the sepsis the coagulation cascade, the complement system and the activation system are activated, in different moments, and this contributes to the development of multiple organ failure. This activation involves all system specially in late sepsis and contributes to the development of multiple organ failure associated with high mortality rate. Linezolid ia a one of a new class of antimicrobials (oxazolidinones) for the treatment of gram positive infection such as nosocomial pneumonia (including MRSA), community acquired pneumonia, complicate and unco…
Real-world experience with dupilumab in severe asthma: One-year data from an italian named patient program
2021
Raffaele Campisi,1 Claudia Crimi,1 Santi Nolasco,2 Bianca Beghè,3 Leonardo Antonicelli,4 Gabriella Guarnieri,5 Nicola Scichilone,6 Morena Porto,2 Luigi Macchia,7 Giulia Scioscia,8 Maria Pia Foschino Barbaro,8 Alberto Papi,9 Nunzio Crimi1,2 1Respiratory Medicine Unit, A.O.U. Policlinico “G. Rodolico -San Marco”, Catania, Italy; 2Department of Clinical and Experimental Medicine, Section of Respiratory Diseases, University of Catania, Catania, Italy; 3Respiratory Medicine Unit, Department of Medicine, University of Modena and Reggio Emilia, Modena, Italy; 4Allergy Unit, Department of Internal Medicine, Ancona University Hospital, Ancona, Italy; 5Department of Car…
Mentalizing eye contact with a face on a video : Gaze direction does not influence autonomic arousal
2018
Recent research has revealed enhanced autonomic and subjective responses to eye contact only when perceiving another live person. However, these enhanced responses to eye contact are abolished if the viewer believes that the other person is not able to look back at the viewer. We purported to investigate whether this “genuine” eye contact effect can be reproduced with pre‐recorded videos of stimulus persons. Autonomic responses, gaze behavior, and subjective self‐assessments were measured while participants viewed pre‐recorded video persons with direct or averted gaze, imagined that the video person was real, and mentalized that the person could see them or not. Pre‐recorded videos did not …
Impressions of Questionable Marketing Practices in Indonesia: The Influence of Gender and Social Desirability Response Bias
2008
Our research examines the ethical sensitivity of 90 Indonesian business students (61 male and 29 female) toward questionable marketing practices using self-reported data; however, unlike most ethics research, we control for social desirability responsibility bias. In our research, we found that, when social desirability response bias was not considered, there was a significant gender difference. However, we also found that female students scored significantly higher on our measure of social desirability response bias than did their male counterparts. When we considered both gender and social desirability response bias in our models, the differences in ethical sensitivity between genders wer…
Intergenerational fitness effects of the early life environment in a wild rodent
2019
The early life environment can have profound, long‐lasting effects on an individual's fitness. For example, early life quality might (a) positively associate with fitness (a silver spoon effect), (b) stimulate a predictive adaptive response (by adjusting the phenotype to the quality of the environment to maximize fitness) or (c) be obscured by subsequent plasticity. Potentially, the effects of the early life environment can persist beyond one generation, though the intergenerational plasticity on fitness traits of a subsequent generation is unclear. To study both intra‐ and intergenerational effects of the early life environment, we exposed a first generation of bank voles to two early life…
Implications of heat waves on immune defence, life history traits, and adaptive potential : a snail's perspective
2014
Overexpression of SAMDC1 gene in Arabidopsis thaliana increases expression of defense-related genes as well as resistance to Pseudomonas syringae and…
2014
It has been previously described that elevation of endogenous spermine levels in Arabidopsis could be achieved by transgenic overexpression of S-Adenosylmethionine decarboxylase (SAMDC) or Spermine synthase (SPMS). In both cases, spermine accumulation had an impact on the plant transcriptome, with up-regulation of a set of genes enriched in functional categories involved in defense-related processes against both biotic and abiotic stresses. In this work, the response of SAMDC1-overexpressing plants against bacterial and oomycete pathogens has been tested. The expression of several pathogen defense-related genes was induced in these plants as well as in wild type plants exposed to an exogeno…
Tryptophan metabolic pathways and brain serotonergic activity: A comparative review
2019
The essential amino acid L-tryptophan (Trp) is the precursor of the monoaminergic neurotransmitter serotonin (5-hydroxytryptamine, 5-HT). Numerous studies have shown that elevated dietary Trp has a suppressive effect on aggressive behavior and post-stress plasma cortisol concentrations in vertebrates, including teleosts. These effects are believed to be mediated by the brain serotonergic system, even though all mechanisms involved are not well understood. The rate of 5-HT biosynthesis is limited by Trp availability, but only in neurons of the hindbrain raphe area predominantly expressing the isoform TPH2 of the enzyme tryptophan hydroxylase (TPH). In the periphery as well as in brain areas …
Relaxing effects of music and odors on physiological recovery after highly demanding executive tasks
2021
International audience
Tryptophan Metabolic Pathways and Brain Serotonergic Activity: A Comparative Review
2019
The essential amino acid L-tryptophan (Trp) is the precursor of the monoaminergic neurotransmitter serotonin (5-hydroxytryptamine, 5-HT). Numerous studies have shown that elevated dietary Trp has a suppressive effect on aggressive behavior and post-stress plasma cortisol concentrations in vertebrates, including teleosts. These effects are believed to be mediated by the brain serotonergic system, even though all mechanisms involved are not well understood. The rate of 5-HT biosynthesis is limited by Trp availability, but only in neurons of the hindbrain raphe area predominantly expressing the isoform TPH2 of the enzyme tryptophan hydroxylase (TPH). In the periphery as well as in brain areas …