Search results for " risc"
showing 10 items of 257 documents
Leisure-time physical activity, sedentary behaviors, sleep, and cardiometabolic risk factors at baseline in the PREDIMED-PLUS intervention trial: A c…
2017
Limited data exists on the interrelationships between physical activity (PA), sedentary behaviors and sleep concerning cardiometabolic risk factors in aged adults at high cardiovascular disease risk. Our aim was to examine independent and joint associations between time spent in leisure-time PA, sedentary behaviors and sleep on the prevalence of obesity, type 2 diabetes (T2D) and components of the metabolic syndrome (MetS) in Mediterranean individuals at high cardiovascular risk. Cross-sectional analyses were performed on baseline data from 5776 Spanish adults (aged 55-75y in men; 60-75y in women) with overweight/ obesity and MetS, from October 2013 to October 2016, in the PREDIMED-PLUS tri…
Utilizzo di modelli lineari generalizzati nella derivazione di mappe di suscettibilità per il rischio idrogeologico
2010
L’analisi statistica basata sulla correlazione tra cause e occorrenze, costituisce uno degli approcci più utilizzati in letteratura scientifica per la valutazione delle aree propense a produrre dissesti idrogeologici. Tra questi, il dissesto da frana rappresenta uno tra i più pericolosi e dannosi eventi naturali che negli ultimi anni hanno particolarmente colpito tutto il territorio nazionale. Il presente lavoro si pone come obiettivo quello di valutare l’efficienza di un modello statistico multivariato per la determinazione di mappe di suscettibilità al rischio idrogeologico, basandosi sulla correlazione tra fattori innescanti e occorrenze. Tra i modelli statistici presenti in letteratura …
Consideraciones sobre la relación mente-cuerpo en el proceso del parto
2023
Analizo algunos aspectos clave del modelo médico del parto, centrándome especialmente en los presupuestos que parece albergar sobre la relación mente-cuerpo. En primer lugar, examino las visiones del modelo médico como un modelo dualista ontológico. En contra de las críticas habituales a este dualismo, que sostienen que ha llevado a tratar el cuerpo de parto como una máquina ¿rastreando, además, hasta Descartes el origen de este enfoque¿, defiendo que el problema no reside en el propio dualismo, sino en que se obvia la interacción mente-cuerpo: son las propias personas de parto quienes se tratan como máquinas. En segundo lugar, analizo la centralidad de la noción de riesgo en el modelo médi…
Mycotoxin mixtures in food and feed: a holistic, innovative, flexible modelling approach for risk assessment MYCHIF
2019
Mycotoxin contamination can occur in many agricultural products both destined to food and feed. Mycotoxins are produced as the result of fungal metabolism and plant-pathogen interaction. Therefore, many structurally-related congeners, defined as modified mycotoxins are generated by plant &/or fungi metabolism, or food processing, and coexist with their native forms. Studies investigating the co-occurrence of multiple-mycotoxins reported 75%100% of samples containing more than one mycotoxin, referring to native compounds and 100% reported multiple modified forms. A major challenge in a risk assessment is to depict the biosynthesis of mycotoxin mixtures and their realistic occurrence. Over th…
STUDIO DI ASSOCIAZIONE FRA DISLIPIDEMIA, SINDROMI COGNITIVE AMNESTICHE PRE-DEMENZA E MALATTIA DI ALZHEIMER: DATI DI POPOLAZIONE DELLO ZABÙT AGING PRO…
Global, regional, and national burden of mortality associated with non-optimal ambient temperatures from 2000 to 2019: a three-stage modelling study
2021
Background: Exposure to cold or hot temperatures is associated with premature deaths. We aimed to evaluate the global, regional, and national mortality burden associated with non-optimal ambient temperatures. Methods: In this modelling study, we collected time-series data on mortality and ambient temperatures from 750 locations in 43 countries and five meta-predictors at a grid size of 0·5° × 0·5° across the globe. A three-stage analysis strategy was used. First, the temperature–mortality association was fitted for each location by use of a time-series regression. Second, a multivariate meta-regression model was built between location-specific estimates and meta-predictors. Finally, the gri…
Tecniche di intervento per il recupero strutturale
2021
La tutela del patrimonio storico-architettonico esistente si configura quale esigenza imprescindibile al fine di preservare l’identità storica e culturale dei luoghi. I numerosi eventi sismici che negli ultimi decenni hanno interessato il territorio italiano hanno messo in evidenza l’elevata vulnerabilità dell’edificato esistente ed hanno posto l’accento sulla necessità di programmare e realizzare interventi mirati alla riduzione di tale vulnerabilità. In particolare, i maggiori danni provocati da eventi sismici si riscontrano nei centri storici dove la quasi totalità delle costruzioni è realizzata in muratura con tecniche costruttive molto spesso non adeguate a fronteggiare gli effetti del…
NUOVE STRATEGIE TERAPEUTICHE E DIAGNOSTICHE PER IL MANAGEMENT DEL RISCHIO CARDIO-METABOLICO IN PAZIENTI CON NAFLD CON O SENZA DIABETE MELLITO TIPO 2
Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies
2020
AbstractEating disorders and substance use disorders frequently co-occur. Twin studies reveal shared genetic variance between liabilities to eating disorders and substance use, with the strongest associations between symptoms of bulimia nervosa (BN) and problem alcohol use (genetic correlation [rg], twin-based=0.23-0.53). We estimated the genetic correlation between eating disorder and substance use and disorder phenotypes using data from genome-wide association studies (GWAS). Four eating disorder phenotypes (anorexia nervosa [AN], AN with binge-eating, AN without binge-eating, and a BN factor score), and eight substance-use-related phenotypes (drinks per week, alcohol use disorder [AUD], …