Search results for " sample"

showing 10 items of 456 documents

Oxyphytosterols are present in plasma of healthy human subjects

2004

The oxidised derivatives of phytosterols (oxyphytosterols) were identified in plasma samples from thirteen healthy human volunteers, using MS. All the samples contained noticeable quantities of (24R)-5b,6b-epoxy-24-ethylcholestan-3b-ol (b-epoxysitostanol) and (24R)-ethylcholestan-3b,5a,6b-triol (sitostanetriol) and also trace levels of (24R)-5a,6a-epoxy-24-ethylcholestan-3b-ol (a-epoxysitostanol), (24R)-methylcholestan-3b,5a,6b-triol (campestanetriol) and (24R)-ethylch olest-5-en-3b-ol-7-one(7-ketositosterol). The amounts of these oxyphytosterols in plasma varied from 4·8 to 57·2 ng/ml. There are two possibilities concerning the origin of these compounds. First, they could come from the sma…

AdultMaleMedicine (miscellaneous)Mass spectrometryGas Chromatography-Mass Spectrometry03 medical and health sciences0404 agricultural biotechnologyBlood plasmaHumansComputingMilieux_MISCELLANEOUS030304 developmental biology0303 health sciencesNutrition and DieteticsChromatographyPlasma samplesChemistryHealthy subjectsPhytosterols04 agricultural and veterinary sciencesMiddle AgedSitosterols040401 food science3. Good health[SDV.AEN] Life Sciences [q-bio]/Food and NutritionHuman plasmaFemaleOxidation-Reduction[SDV.AEN]Life Sciences [q-bio]/Food and NutritionBritish Journal of Nutrition
researchProduct

Differences and Similarities between Allergic and Nonallergic Rhinitis in a Large Sample of Adult Patients with Rhinitis Symptoms

2010

<i>Background:</i> Allergic rhinitis (AR) and nonallergic rhinitis (NAR) may present with different clinical and laboratory characteristics. <i>Methods:</i> A total of 1,511 consecutive patients, aged 18–81 years, diagnosed with rhinitis, 56% females and 44% males, underwent complete allergic evaluation including skin prick test, blood eosinophil counts, nasal eosinophil counts, peak nasal inspiratory flow (PNIF) measurement and evaluation of nasal symptoms using a visual analog scale (VAS). <i>Results:</i> A total of 1,107 patients (73%)had AR, whereas 404 (27%) had NAR. Patients with NAR were older and predominantly female. A higher nasal eosinophils co…

AdultMaleNasal eosinophilAgingAllergyRhinitis Allergic PerennialSkin prick testPeak nasal inspiratory flowAdolescentNon allergic rhinitisVisual analogue scaleNon-allergic rhinitisImmunologyHistamine AntagonistsReceiver operating characteristicSettore MED/42 - Igiene Generale E ApplicataSeverity of Illness IndexAllergic rhinitisYoung AdultSex FactorsNonallergic rhinitisBlood eosinophilAllergic rhinitis; Non allergic rhinitis; Skin prick test; Peak nasal inspiratory flow; Blood eosinophil; Nasal eosinophil; Visual analog scale; Receiver operating characteristicHumansImmunology and AllergyMedicineAllergic rhinitis Non allergic rhinitis Skin prick test Peak nasal inspiratory flow Blood eosinophil Nasal eosinophil Visual analog scale Receiver operating characteristicVisual analog scaleYoung adultAgedRhinitisSkin TestsAged 80 and overAdult patientsbusiness.industryHeadacheGeneral MedicineMiddle AgedEosinophilConjunctivitismedicine.diseaseLarge sampleEosinophilsmedicine.anatomical_structureSettore MED/31 - OtorinolaringoiatriaImmunologyFemaleNasal Obstructionbusiness
researchProduct

The latent nature of prolonged grief - A taxometric analysis: Results from a representative population sample

2017

Individuals suffering from prolonged grief disorder (PGD) show severe grief reactions after the death of a significant other, even beyond a period of grieving that is within a person's cultural and religious context. In addition to this core element, PGD can manifest in various ways. Symptoms may include persistent preoccupation, intense emotional pain, or impairment in important life domains. The symptoms, furthermore, have to be of culturally or religiously inappropriate extent or severity, taking into account different norms of grieving. PGD is discussed as a distinct diagnostic category in the revision of the International Classification of Diseases (ICD-11). Nosology of PGD has been hi…

AdultMaleNosology050103 clinical psychologyAdolescentInclusion (disability rights)Population samplemedia_common.quotation_subjectContext (language use)Prolonged grief disorderYoung Adult03 medical and health sciences0302 clinical medicineInternational Classification of DiseasesGermanySurveys and QuestionnairesHumans0501 psychology and cognitive sciencesBiological PsychiatryAgedmedia_commonAged 80 and overConceptualizationMental Disorders05 social sciencesMiddle Agedrespiratory system030227 psychiatryPsychiatry and Mental healthPopulation SurveillanceEtiologyFemalelipids (amino acids peptides and proteins)GriefGriefPsychologyBereavementClinical psychologyPsychiatry Research
researchProduct

Assessing thoraco-pelvic covariation in Homo sapiens and Pan troglodytes: A 3D geometric morphometric approach

2019

[Objectives]: Understanding thoraco-pelvic integration in Homo sapiens and their closest living relatives (genus Pan) is of great importance within the context of human body shape evolution. However, studies assessing thoraco-pelvic covariation across Hominoidea species are scarce, although recent research would suggest shared covariation patterns in humans and chimpanzees but also species-specific features, with sexual dimorphism and allometry influencing thoraco-pelvic covariation in these taxa differently.

AdultMalePan troglodytesIntegrationTroglodytesContext (language use)PLSAnthropology PhysicalPelvisYoung AdultImaging Three-DimensionalmedicineAnimalsHumansChimpanzeesMorphometricsSex CharacteristicsbiologyHominoideaTorsoSmall sampleTorsoThoraxbiology.organism_classificationbody regionsSexual dimorphismAnatomy Comparativemedicine.anatomical_structureEvolutionary biologyHomo sapiensAnthropologyFemaleAllometryAnatomyTomography X-Ray ComputedAmerican Journal of Physical Anthropology
researchProduct

Psychometric properties of the Spanish version of the family-centred practices scale for use with families of young children receiving early childhoo…

2018

Background Early childhood intervention (ECI) centres in Spain recently initiated a process of change towards the adoption of family-centred practices (FCPs). Knowledge about the extent to which practitioners' use FCPs is needed. The psychometric properties of the Spanish version of the FCPs scale were examined. Method A convenience sample of 105 families of children with developmental delays attending three different ECI centres in Spain completed the FCPs scale and provided information about the ECI centre characteristics and practices, caregiver self-efficacy beliefs, and family and child demographic information. Results The Spanish version of the FCP scale was found to be both reliable …

AdultMaleParentsPsychometricsPsychometricsDevelopmental DisabilitiesConvenience sampleEducationDevelopmental psychologyIntervention (counseling)Developmental and Educational PsychologyFamily centredEarly Intervention EducationalHumans0501 psychology and cognitive sciencesSelf-efficacy05 social sciences050301 educationReproducibility of ResultsSpanish versionMiddle AgedSelf EfficacySpainScale (social sciences)Early childhood interventionFemalePsychology0503 education050104 developmental & child psychologyJournal of applied research in intellectual disabilities : JARID
researchProduct

Detection of gastric atrophy by circulating pepsinogens: A comparison of three assays.

2017

Background Circulating levels of pepsinogens have been used in high gastric cancer-risk Asian and European populations to triage endoscopic evaluation for more severe pathology. There are different analytic methods with uncertain correlations. We therefore compared diagnostic performance of three commonly used pepsinogen assays to detect histologically confirmed gastric atrophy. Methods We tested plasma samples from adult patients with (n=50) and without (n=755) moderate or severe gastric corpus atrophy, as determined histologically by consensus of three expert pathologists. A single laboratory measured pepsinogens I (PgI) and II (PgII) using commercially available assays: two ELISA assays …

AdultMalePathologymedicine.medical_specialtyAdolescentStomach DiseasesEnzyme-Linked Immunosorbent AssayGastroenterologyArticle03 medical and health sciencesYoung Adult0302 clinical medicineAtrophyPepsinInternal medicineMedicineHumansAgedAged 80 and overAdult patientsPlasma samplesReceiver operating characteristicbiologyPepsinogensbusiness.industryDiagnostic Tests RoutineHistocytochemistryGastric AtrophyStomachGastroenterologyGeneral MedicineMiddle Agedmedicine.diseasedigestive system diseasesInfectious Diseasesmedicine.anatomical_structureROC CurveGastric Mucosa030220 oncology & carcinogenesisbiology.protein030211 gastroenterology & hepatologyTest performanceFemaleAtrophybusinessLatex Fixation TestsHelicobacter
researchProduct

Clinical features, disease progression and use of healthcare resources in a large sample of 866 patients from 24 headache centers: A real-life perspe…

2021

Objective: To develop a dedicated Italian chronic migraine (CM) database (IRON project) to overcome disease misconceptions, improve clinical administration, reduce patients' burden, and rationalize economic resource allotment.Background: Proper CM management requires a comprehensive appraisal of its full clinical, social, and economic complexity.Methods: In this cross-sectional study, CM patients were screened in 24 certified headache centers with face-to-face interviews. Information on sociodemographic factors, medical history, characteristics of CM, and of prior episodic migraine (EM), and healthcare resource use was gathered using a semistructured web-based questionnaire.Results: A total…

AdultMalePediatricsmedicine.medical_specialtyDatabases FactualMigraine DisordersDiseaseregistryState Medicine03 medical and health sciences0302 clinical medicineChronic MigraineSurveys and QuestionnairesHealth caremedicineHumansMass ScreeningMedical history030212 general & internal medicinedatabaseEconomic complexitybusiness.industryDisease progressionhealthcareMiddle AgedPatient Acceptance of Health CareLarge sampleCross-Sectional StudiesNeurologyItalySocioeconomic Factorseconomic burdenDisease ProgressionResource usePain ClinicsFemaleSettore MED/26 - NeurologiaNeurology (clinical)chronic migrainebusiness030217 neurology & neurosurgery
researchProduct

The occupational role of dental conditions among a consecutive sample of Spanish workers

2010

Objectives: To assess the occupational impact of the mouth in terms of days of work loss in the last year and the perception of the working performance disturbance because of the oral conditions. Study design: A consecutive sample (n=269) of the Regional Government staff of the province of Granada (Spain) was recruited. Participants were asked about work loss related to health problems in the past 12 months, capturing the aetiological entities, the frequency of the work absent and the total days loss. Also subjects reported if they believed that mouth affects their occupational performance, and if they have perceived difficulties for carrying out work because of the mouth. Data on sociodemo…

AdultMalePediatricsmedicine.medical_specialtyOral HealthOral healthCONSECUTIVE SAMPLEOral and maxillofacial pathologymedicineHumansGeneral DentistryOccupational HealthAgedDenture wearersbusiness.industryOdds ratioMiddle Aged:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseOtorhinolaryngologySpainRelative riskUNESCO::CIENCIAS MÉDICASSick leaveEtiologyFemaleSurgerySick LeavebusinessDemographyMedicina Oral Patología Oral y Cirugia Bucal
researchProduct

Accuracy of two plasma antibody tests and faecal antigen test for non-invasive detection of H. pylori in middle-aged Caucasian general population sam…

2018

The aim of the study was to assess the accuracy of two plasma Helicobacter pylori (H. pylori) antibody test-systems and a stool antigen test (SAT) system in a general population sample in Latvia.Blood and faecal samples were analysed in healthy individuals (40-64 years), referred for upper gastrointestinal endoscopy according to pilot study protocol within a population-based study investigating gastric cancer prevention strategies (GISTAR pilot study). Antibodies to H. pylori were assessed in plasma by latex-agglutination test and enzyme-linked immunosorbent assay (ELISA). H. pylori antigen in faecal samples was detected by a monoclonal enzyme immunoassay-based SAT. Histological assessment …

AdultMalePopulation sampleEnzyme-Linked Immunosorbent AssayPilot ProjectsSensitivity and SpecificityHelicobacter Infections03 medical and health sciencesFeces0302 clinical medicineMedicineHumansSerologic TestsAntigens BacterialbiologyHelicobacter pyloribusiness.industryNon invasiveGastroenterologyHelicobacter pyloriMiddle Agedbacterial infections and mycosesbiology.organism_classificationAntigen testAntibodies BacterialLatex fixation testROC Curve030220 oncology & carcinogenesisImmunologybiology.proteinStool antigen030211 gastroenterology & hepatologyFemaleFranceAntibodybusinessScandinavian journal of gastroenterology
researchProduct

Liking for fat is associated with sociodemographic, psychological, lifestyle and health characteristics

2014

Sensory liking influences dietary behaviour, but little is known about specifically associated individual profiles. The aim of the present study was to investigate the associations between liking for fat-and-salt and fat-and-sweet sensations and sociodemographic, economic, psychological, lifestyle and health characteristics in a large sample. Individual characteristics and liking scores were collected by a questionnaire among 37 181 French adults. Liking scores were constructed using a validated preference questionnaire. Multinomial logistic regression models were used to assess the associations between liking levels and individual characteristics. In both sexes, subjects belonging to low-l…

AdultMaleRisklikingAdolescent[ SDV.AEN ] Life Sciences [q-bio]/Food and Nutritionhabitude alimentairesociodemographic factorsMedicine (miscellaneous)enquêteHyperphagiapsychological factorsBody Mass IndexCohort StudiesFood PreferencesYoung AdultSurveys and Questionnaires[ SDV.MHEP ] Life Sciences [q-bio]/Human health and pathologyfatSensationHumansObesitysantéLife StyleAgedMultinomial logistic regressionAged 80 and overInternetNutrition and DieteticssociologieCognitionMiddle AgedDietary FatssociodémographiePreferenceLarge sampleobésitéSocioeconomic FactorsFemaleObese subjectsFrancedietary determinantsPsychology[SDV.AEN]Life Sciences [q-bio]/Food and Nutrition[SDV.MHEP]Life Sciences [q-bio]/Human health and pathologyFollow-Up StudiesClinical psychology
researchProduct