Search results for " sigma"
showing 10 items of 76 documents
"Table 35" of "Studies of quantum chromodynamics with the ALEPH detector"
1997
Fragmentation distribution for SIGMA(1385) production.
Advanced Statistical Tools for Six Sigma and other Industrial Applications
Six Sigma is a methodological approach and philosophy for quality improvement in operations management; its main objectives are identifying and removing the causes of defects, and minimizing variability in manufacturing and business processes. To do so, Six Sigma combines managerial and statistical tools, with the creation of a dedicated organizational structure. In this doctoral thesis and the three years of study and research, we have had the purpose to advance the potential applications of the methodology and its tools; with a specific attention on issues and challenges that typically prevent the realization of the expected financial and operational gains that a company pursue in applyin…
Bond-based 3D-chiral linear indices: Theory and QSAR applications to central chirality codification
2008
The recently introduced non-stochastic and stochastic bond-based linear indices are been generalized to codify chemical structure information for chiral drugs, making use of a trigonometric 3D-chirality correction factor. These improved modified descriptors are applied to several well-known data sets to validate each one of them. Particularly, Cramer's steroid data set has become a benchmark for the assessment of novel quantitative structure activity relationship methods. This data set has been used by several researchers using 3D-QSAR approaches such as Comparative Molecular Field Analysis, Molecular Quantum Similarity Measures, Comparative Molecular Moment Analysis, E-state, Mapping Prope…
Application of Lean Six Sigma methodology to a school based immunization project in Italy
2015
Mejora de la calidad y seguridad del proceso farmacoterapéutico del paciente onco-hematológico atendido en el hospital de día, aplicando la metodolog…
2018
El objetivo principal de la presente Tesis Doctoral fue mejorar la calidad y la seguridad del proceso farmacoterapéutico del paciente onco-hematológico atendido en el hospital de día aplicando la metodología Lean Seis Sigma, para disminuir los tiempos de demora del proceso farmacoterapéutico, reducir los errores de medicación, aumentar la satisfacción de los pacientes y reducir los costes del servicio prestado. Se realizó un estudio analítico, longitudinal prospectivo de 4 años de duración, basado en métodos de observación directa y estudios experimentales. Se incluyó el proceso farmacoterapéutico antineoplásico integral con quimioterapia intravenosa del paciente onco-hematológico atendido …
Starpfunkcionālu komandu veidošana biznesa organizācijās
2019
Šajā pētījumā galvenā uzmanība pievērsta savstarpēji funkcionējošu komandu izveidošanai mazos uzņēmumos un to analīzei, izmantojot izmaksu un ieguvumu analīzi. Turklāt pētījums ir arī vērsts uz problēmu noteikšanu sākotnējā posmā. Caur pētījumiem un precīzu datu analīzi bija noskaidrota nepieciešamība starpfunkcionālu komanu veidošanai. Pamatojoties uz pierādījumiem, kuri ir sniegti pēc visu pētījumu procedūru pabeigšanas, uzņēmums var pieņemt lēmumu. Šī pētījuma rezultāti atklāj vairākus faktorus, kas būtiski ietekmēja darbiniekus, kuri strādā dažādās struktūrvienībās: spēju efektīvi sazināties un dibināt ciešas attiecības ar citiem, lai sasniegtu kopējo mērķi. Pirmajā nodaļā ir aplūkota s…
Lopputuotteen laadunvalvonnan parantaminen tietojärjestelmien avulla
2009
Tekijä: Antti Hyvönen Yhteystiedot: anerhyvo@jyu.fi Työn nimi: Lopputuotteen laadunvalvonnan parantaminen tietojärjestelmien avulla Title in English: Enhancing quality management through IT Työ: Tietojärjestelmätiede kandidaatintutkielma Sivumäärä: 34 Tiivistelmä: Yritysten valmistamilla tuotteilla on oma elinkaarensa. Tällaisille tuotteille laadunvalvonta on keskeistä kaikissa tuotteen elinkaaren vaiheissa. Laatua parannettaessa informaatio näyttelee tärkeää roolia tässä prosessissa. Tälläista tietoa voidaan kerätä tuotannon eri vaiheista, aina asiakkaalta tulevaan palautteeseen saakka. Itse tiedon keräyksessä ja analysoinnissa tietotekniikka voi olla suureksi eduksi. Tällä tutkielmalla on…
Searching for signatures around 1920 MeV of a N-* state of three hadron nature
2009
We provide a series of arguments which support the idea that the peak seen in the gamma p -> K+ Lambda reaction around 1920 MeV should correspond to the recently predicted state of J(P) = 1/2(+) as a bound state of K(K) over bar N with a mixture of alpha(0)(980)N and f(0)(980)N components. At the same time we propose polarization experiments in that reaction as a further test of the prediction, as well as a study of the total cross-section for gamma p -> K(+)K(-)p at energies close to threshold and of d sigma/dM(inv) for invariant masses close to the two-kaon threshold.
Sigma-1 Receptor Activation Induces Autophagy and Increases Proteostasis Capacity In Vitro and In Vivo
2019
Dysfunction of autophagy and disturbed protein homeostasis are linked to the pathogenesis of human neurodegenerative diseases and the modulation of autophagy as the protein clearance process has become one key pharmacological target. Due to the role of sigma-1 receptors (Sig-1R) in learning and memory, and the described pleiotropic neuroprotective effects in various experimental paradigms, Sig-1R activation is recognized as one potential approach for prevention and therapy of neurodegeneration and, interestingly, in amyotrophic lateral sclerosis associated with mutated Sig-1R, autophagy is disturbed. Here we analyzed the effects of tetrahydro-N,N-dimethyl-2,2-diphenyl-3-furanmethanamine hyd…
TCH-039 Six Sigma in Healthcare: An Application in the Monitoring of Albumin
2013
Background The high off-label use of albumin persuaded the pharmacy to introduce a request form that uses the internationals guidelines to assess whether the use of albumin is appropriate. This has resulted in a clear reduction in the costs. Purpose To monitor the wards using six sigma methodology (a statistical concept that measures a process in terms of defects); to ensure that all procedures have been followed correctly. Materials and Methods 696 forms for albumin prescriptions coming from 26 wards (August to December 2011) were analysed using Minitab software, which cheques the frequency of the best correct requests (type 1), partially correct requests (type 2) and incorrect requests (t…