Search results for " simple"
showing 10 items of 180 documents
The effect of Dextransulfate 500 on the pathogenesis of herpes simplex virus infections in weanling mice
1978
Intraperitoneal (i.p.) injection of Dextran Sulfate (D.S.) 500 during a limited period of time influences the course of herpes simplex-virus-infections. D.S.500 was found to reduce the resistance of mice for some herpes simplex-virus strains (Len, L3-2s, Haase) if given between 16 hours before and 2 hours after i.p. infection. The decrease of resistance could be correlated with an increase of the virus content of liver, spleen, brain and spinal cord. Injection of herpes simplex-virus-specific immune serum counteracted the effect of D.S.500 on the course of infections. Conversely, D.S.500 increased the resistance of mice to another group of herpes simplex-viruses (strains D-316, Thea, DD), i…
Infections of susceptible and resistant mouse strains with herpes simplex virus type 1 and 2.
1980
The spread of HSV of type 1 and 2 was investigated after intraperitoneal, intraplantar and intracerebral infections of resistant (C57/bl) and susceptible (NMRI) mice. The virus spreads after i.p. infection to the spleen and the liver to the same extent in both strains of mice. However, virus is eliminated earlier in resistant mice. Intracerebral infections revealed a peculiar type of resistance of C57/bl mice especially for type 2 of HSV. HSV multiplies in the thymus at the early stage of infection and can be detected in this organ in sick mice of NMRI strain. HSV-1 and 2 can be detected in the spinal cord of C57/bl mice without sickness or death of these animals.
Congenital myopathy and epidermolysis bullosa due to PLEC variant
2021
Abstract We report on an adult Turkish patient with mild myopathy with a fiber-type disproportion and mitochondrial disorganization caused by genetic variants in the plectin gene (PLEC). Molecular genetic panel testing revealed two homozygous variants in PLEC (NM_000445.4): c.8306C>G (p.Pro2769Arg) and c.7506 + 5C>G (p. ?) that were classified as variants of unknown significance (class 3) following ACMG guidelines for variant classification in genetic diagnostics. A thorough reassessment of the patient revealed mild skin blistering (epidermolysis bullosa simplex, EBS). This illustrates the importance of deep phenotyping of neuromuscular patients.
Evaluer les choix d'itinéraires en milieu urbain
2007
ACL; International audience; La revalorisation de la marche à pied comme mode de déplacement en milieu urbain implique que l'on dispose de connaissances toujours plus précises sur les pratiques des piétons, notamment en ce qui concerne les choix d'itinéraires parmi un ensemble d'alternatives potentielles. Dans cette perspective, nous proposons d'appliquer aux déplacements piétonniers les modèles d'affectation probabilistes de flux, habituellement utilisés pour les modes de transport motorisés. Ces modèles sont fondés sur des hypothèses relatives au comportement des individus ; à ce titre, nous les considérons comme des outils de simulation permettant de tester des comportements pédestres va…
A Gaschütz–Lubeseder Type Theorem in a Class of Locally Finite Groups
1999
The aim of this paper is to present a Gaschutz–Lubeseder type theorem in the class cL of all radical locally finite groups satisfying min−p for all primes p. Notice that these groups are countable and co-Hopfian by [1, (5.4.8)]. In retrospect, the theory of saturated formations of finite soluble groups began with the results of Gaschutz [3] in 1963. He introduced the concept of “covering subgroup” as a generalization of Sylow and Hall subgroups. These covering subgroups have many of the properties of Sylow and Hall subgroups other than the arithmetic ones. The main idea of Gaschutz’s work was concerned with group theoretical classes having the same properties. He defined a formation F to be…
Operators in Rigged Hilbert Spaces, Gel’fand Bases and Generalized Eigenvalues
2022
Given a self-adjoint operator A in a Hilbert space H, we analyze its spectral behavior when it is expressed in terms of generalized eigenvectors. Using the formalism of Gel’fand distribution bases, we explore the conditions for the generalized eigenspaces to be one-dimensional, i.e., for A to have a simple spectrum.
El edificio gremial de los abaixadors o tundidores, en Valencia
2020
In the ?barri del mercat?, in the city of Valencia and very close to its Lonja, there is a building complex which is the object of this study. The research, carried out from the simple field of toponymy, to the constructive analysis, lead us to suppose that it is the building of the Valencian trade union of cloth-shearers. It can be seen how the building now camouflaged by other subsequent interventions, corresponds to a type that cannot be related to those usually built in the city of Valencia. Its origins clearly from the Valencian self-governing period splendor, its dimensions and the finishes used in its construction seem to refer to a medieval workshop. A structure of great importance …
La preservación del favor filii en supuestos de ruptura de la convivencia de los acogedores, tutores o guardadores del menor
2021
Cuando la guarda del menor por parte de los progenitores no es posible y esta es atribuida de forma conjunta a dos personas convivientes que posteriormente cesan dicha convivencia, resulta necesario determinar cuál de ellas va a ejercer a partir de ese momento las funciones inherentes a dicha guarda. Las posibles soluciones dependerán de si se trata de un supuesto de acogimiento, de tutela o de siempre guarda. When care of the child by the parents is not possible and is attributed jointly to two people living together who subsequently stop living together, it is necessary to determine which of them will exercise the functions inherent to the care from that moment on. The possible solutions …
Reliable Outer Bounds for the Dual Simplex Algorithm with Interval Right-hand Side
2013
International audience; In this article, we describe the reliable computation of outer bounds for linear programming problems occuring in linear relaxations derived from the Bernstein polynomials. The computation uses interval arithmetic for the Gauss-Jordan pivot steps on a simplex tableau. The resulting errors are stored as interval right hand sides. Additionally, we show how to generate a start basis for the linear programs of this type. We give details of the implementation using OpenMP and comment on numerical experiments.
Soft X-ray Tomography Reveals HSV-1-Induced Remodeling of Human B Cells.
2022
Upon infection, viruses hijack the cell machinery and remodel host cell structures to utilize them for viral proliferation. Since viruses are about a thousand times smaller than their host cells, imaging virus-host interactions at high spatial resolution is like looking for a needle in a haystack. Scouting gross cellular changes with fluorescent microscopy is only possible for well-established viruses, where fluorescent tagging is developed. Soft X-ray tomography (SXT) offers 3D imaging of entire cells without the need for chemical fixation or labeling. Here, we use full-rotation SXT to visualize entire human B cells infected by the herpes simplex virus 1 (HSV-1). We have mapped the temporo…