Search results for " solution"

showing 10 items of 3084 documents

Partition of Indicaxanthin in Membrane Biomimetic Systems. A Kinetic and Modeling Approach

2009

The solubilization site of indicaxanthin (Ind) in lipid bilayers was investigated by the kinetics of Ind oxidation by peroxyl radicals in water and in aqueous/L-alpha-dipalmitoyl-phosphatidylcholine (DPPC) vesicles, pH 7.4, and 37.0 and 48.0 degrees C, that is, in a gel-like and a crystal liquidlike bilayer state, respectively. The time-dependent Ind absorbance decay, matched with a successful simulation of the reaction kinetic mechanism by Gepasi software, supported a multistep pathway. Computer-assisted analysis allowed calculation of the rate constants associated with the reactions involved, the values of which decreased with increasing DPPC concentration. The binding constant calculated…

12-DipalmitoylphosphatidylcholinePyridinesLipid BilayersBetalain pigmentchemistry.chemical_compoundReaction rate constantGepasi simulation.biomimetic membraneLipid bilayervesiclephospholipidAqueous solutionChromatographyVesicleBilayerAqueous two-phase systemWaterGeneral ChemistryBinding constantBetaxanthinsPeroxidesKineticschemistryLiposomesPhysical chemistryDPPCGeneral Agricultural and Biological SciencesOxidation-ReductionIndicaxanthinSoftware
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Interaction of Novel Metal Complexes with DNA: Synthetic and Structural Aspects

2009

Metal ions bind to nucleic acids at various positions. This binding can be modulated by using metal complexes with appropriate ligands. Novel mono- and especially dinuclear metal complexes could be a powerful tool to detect rare, but still physiologically relevant, forms of DNA, e.g. the left-handed Z-DNA. In this review, our recent research activities in this area of bioinorganic chemistry are summarized. A special emphasis is laid on the synthetic challenges that arose upon the synthesis of the polyamine ligands. Further, some rather unusual approaches to elucidate the solution structure of copper bound to guanosine monophosphate with the help of pulsed EPR techniques like ENDOR and HYSC…

10120 Department of ChemistryMono- and dinuclear metal complexesMetal ions in aqueous solutionand dinuclear metal complexes1600 General ChemistrydnaBioinorganic chemistryZ-DNAMetalchemistry.chemical_compoundMono- and Dinuclear Metal ComplexeGuanosine monophosphate540 ChemistryQD1-999Pulsed EPRCrystal structureBioinorganic chemistryGeneral MedicineGeneral ChemistryZ-DNACombinatorial chemistrySettore FIS/07 - Fisica Applicata(Beni Culturali Ambientali Biol.e Medicin)Chemistrychemistryvisual_artCrystal structuresNucleic acidvisual_art.visual_art_mediumMonoSynthetic ChemistryDNAZ
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Crystal and solution structures of di-n-butyltin(IV) complexes of 5-[(E)-2-(4-methoxyphenyl)-1-diazenyl]quinolin-8-ol and benzoic acid derivatives: E…

2009

Abstract Reactions of nBu2SnCl(L1) (1), where L1 = acid residue of 5-[(E)-2-(4-methoxyphenyl)-1-diazenyl]quinolin-8-ol, with various substituted benzoic acids in refluxing toluene, in the presence of triethylamine, yielded dimeric mixed ligand di-n-butyltin(IV) complexes of composition [nBu2Sn(L1)(L2–6)]2 where L2 = benzene carboxylate (2), L3 = 2-[(E)-2-(2-hydroxy-5-methylphenyl)-1-diazenyl]benzoate (3), L4 = 5-[(E)-2-(4-methylphenyl)-1-diazenyl]-2-hydroxybenzoate (4), L5 = 2-{(E)-4-hydroxy-3-[(E)-4-chlorophenyliminomethyl]-phenyldiazenyl}benzoate (5) and L6 = 2-[(E)-(3-formyl-4-hydroxyphenyl)-diazenyl]benzoate (6). All complexes (1–6) have been characterized by elemental analyses, IR, 1H,…

10120 Department of Chemistry[(E)81303 Biochemistry5DenticityStereochemistry12Crystal structuredinBiochemistrybutyltin(IV) complexes(4Inorganic Chemistrychemistry.chemical_compoundPentagonal bipyramidal molecular geometry540 ChemistryMaterials ChemistryCarboxylatePhysical and Theoretical Chemistry2505 Materials ChemistryCoordination geometryXmixed ligandsol1604 Inorganic ChemistryChemistryCrystal structurebenzoic acidOrganic Chemistry5-[(E)-2-(4-methoxyphenyl)-1- diazenyl]quinolin-8-ol Di-n-butyltin(IV) complexes Benzoic acid Mixed ligands Solution and solid-state tin NMR Crystal structureNuclear magnetic resonance spectroscopysolution and solid state tinNMRBond lengthTrigonal bipyramidal molecular geometryCrystallographydiazenyl]quinolinmethoxyphenyl)Settore CHIM/03 - Chimica Generale E Inorganica1606 Physical and Theoretical Chemistry1605 Organic Chemistry
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Coordination abilities of N-methyl alkylaminomethane-1,1-diphosphonic acids towards zinc(II), magnesium(II) and calcium(II) metal ions. Equilibrium s…

2017

Abstract Complex-formation abilities of a series of N-methyl alkylaminomethane-1,1-diphosphonic acids (1–7) with a common tertiary nitrogen atom (CH3−N−R) bearing linear or branched alkyl, cycloheptyl or phenylalkyl R substituents towards zinc(II), magnesium(II) and calcium(II) in aqueous solution have been studied by means of pH-potentiometry, ESI-MS spectrometry, 1H NMR and 31P NMR methods. The obtained results indicate that in the all presented systems mononuclear protonated equimolar and bis complexes are formed. In acidic and neutral solution, the formation of the protonated dinuclear species has been confirmed. The comparative analysis of the potentiometric and NMR data reveal that th…

1H and 31P NMRMetal ions in aqueous solutionInorganic chemistrychemistry.chemical_elementProtonationpH potentiometryZinc010402 general chemistry01 natural sciencesMedicinal chemistrymagnesium(II) and calcium(II) complexesInorganic Chemistrychemistry.chemical_compoundaminomethane-1Materials ChemistryPhysical and Theoretical ChemistryAlkylchemistry.chemical_classificationAqueous solutionzinc(II)010405 organic chemistryMagnesiumESI-MSPhosphonate0104 chemical scienceschemistryProton NMR1-diphosphonic acidsPolyhedron
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PEG 400/Cerium Ammonium Nitrate Combined with Microwave-Assisted Synthesis for Rapid Access to Beta-Amino Ketones. An Easy-to-Use Protocol for Discov…

2018

Compound libraries are important requirement in target-based drug discovery. In the present work, a small focused compound library based on β-aminoketone scaffold has been prepared combining microwave-assisted organic synthesis (MAOS) with polymer-assisted solution phase synthesis (PASPS) and replacing reaction workup standard purification procedures with solid phase extraction (SPE). Specifically, the effects of solvent, such as dioxane, dimethylformamide (DMF), polyethylene glycol 400 (PEG 400), temperature, irradiation time, stoichiometric ratio of reagents, and catalysts (HCl, acetic acid, cerium ammonium nitrate (CAN)) were investigated to maximize both conversion and yield. The optimi…

3003Transcription FactorPharmaceutical ScienceNitratePolyethylene Glycol01 natural sciencesPolyethylene GlycolsPolymer-assisted solution phase synthesiAnalytical Chemistrychemistry.chemical_compoundDrug DiscoveryMannich reactionSolid phase extractionMicrowavesβ-aminoketonesCeriumKetonesKetoneDNA-Binding ProteinsSolventCeriumChemistry (miscellaneous)Molecular MedicineDimethylformamideMicrowave-assisted organic synthesiMannich reaction; β-aminoketones; microwave-assisted organic synthesis; polymer-assisted solution phase synthesis; solid phase extraction; drug discoveryDNA-Binding ProteinBacterial Proteinchemistry.chemical_elementPolyethylene glycol010402 general chemistryArticlelcsh:QD241-441Bacterial Proteinslcsh:Organic chemistryΒ-aminoketonePhysical and Theoretical ChemistrySolid phase extractionpolymer-assisted solution phase synthesisPEG 400Nitrates010405 organic chemistryDrug Discovery3003 Pharmaceutical ScienceOrganic ChemistrySettore CHIM/08 - Chimica FarmaceuticaCombinatorial chemistry0104 chemical scienceschemistryYield (chemistry)microwave-assisted organic synthesisOrganic synthesisMicrowaveTranscription FactorsMolecules
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Solutions of the LPD equation and multi-parametric rogue waves

2022

Quasi-rational solutions to the Lakshmanan Porsezian Daniel equation are presented. We construct explicit expressions of these solutions for the first orders depending on real parameters. We study the patterns of these configurations in the (x, t) plane in function of the different parameters. We observe in the case of order 2, three rogue waves which move according to the two parameters. In the case of order 3, six rogue waves are observed with specific configurations moving according to the four parameters.

47.35.Fg47.10A-47.54.Bdquasi-rational solutions PACS numbers : 33Q5537K10[MATH.MATH-MP] Mathematics [math]/Mathematical Physics [math-ph]Lakshmanan Porsezian Daniel equation
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From particular polynomials to rational solutions to the mKdV equation

2022

Rational solutions to the modified Korteweg-de Vries (mKdV) equation are given in terms of a quotient of determinants involving certain particular polynomials. This gives a very efficient method to construct solutions. We construct very easily explicit expressions of these rational solutions for the first orders n = 1 until 10.

47.35.Fg47.10A-rational solutions PACS numbers : 33Q5547.54.Bd37K10[MATH.MATH-MP] Mathematics [math]/Mathematical Physics [math-ph]mKdV equation
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N order solutions with multi-parameters to the Boussinesq and KP equations and the degenerate rational case

2021

From elementary exponential functions which depend on several parameters, we construct multi-parametric solutions to the Boussinesq equation. When we perform a passage to the limit when one of these parameters goes to 0, we get rational solutions as a quotient of a polynomial of degree N (N + 1) − 2 in x and t, by a polynomial of degree N (N + 1) in x and t for each positive integer N depending on 3N parameters. We restrict ourself to give the explicit expressions of these rational solutions for N = 1 until N = 3 to shortened the paper. We easily deduce the corresponding explicit rational solutions to the Kadomtsev Petviashvili equation for the same orders from 1 to 3.

47.35.Fg47.10A-rational solutions PACS numbers : 33Q55[MATH.MATH-MP]Mathematics [math]/Mathematical Physics [math-ph]47.54.Bd37K10[MATH.MATH-MP] Mathematics [math]/Mathematical Physics [math-ph]Boussinesq equationKadomtsev Petviashvili equation
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From particular polynomials to rational solutions to the PII equation

2022

The Painlevé equations were derived by Painlevé and Gambier in the years 1895 − 1910. Given a rational function R in w, w ′ and analytic in z, they searched what were the second order ordinary differential equations of the form w ′′ = R(z, w, w ′) with the properties that the singularities other than poles of any solution or this equation depend on the equation only and not of the constants of integration. They proved that there are fifty equations of this type, and the Painlevé II is one of these. Here, we construct solutions to the Painlevé II equation (PII) from particular polynomials. We obtain rational solutions written as a derivative with respect to the variable x of a logarithm of a…

47.35.Fg47.54.Bd Painlevé equation II rational solutions determinantsnumbers : 33Q5547.10A-rational solutions47.54.Bd Painlevé equation IIdeterminants37K10[MATH.MATH-MP] Mathematics [math]/Mathematical Physics [math-ph]
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Multi-parameters rational solutions to the mKdV equation

2021

N-order solutions to the modified Korteweg-de Vries (mKdV) equation are given in terms of a quotient of two wronskians of order N depending on 2N real parameters. When one of these parameters goes to 0, we succeed to get for each positive integer N , rational solutions as a quotient of polynomials in x and t depending on 2N real parameters. We construct explicit expressions of these rational solutions for orders N = 1 until N = 6.

47.35.FgNonlinear Sciences::Exactly Solvable and Integrable Systemswronskians47.10A-rational solutions PACS numbers : 33Q55[MATH.MATH-MP]Mathematics [math]/Mathematical Physics [math-ph]47.54.Bd[MATH.MATH-MP] Mathematics [math]/Mathematical Physics [math-ph]37K10mKdV equation
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