Search results for " support"

showing 10 items of 1591 documents

3D DCE-MRI Radiomic Analysis for Malignant Lesion Prediction in Breast Cancer Patients

2022

Rationale and Objectives: To develop and validate a radiomic model, with radiomic features extracted from breast Dynamic Contrast-Enhanced Magnetic Resonance Imaging (DCE-MRI) from a 1.5T scanner, for predicting the malignancy of masses with enhancement. Images were acquired using an 8-channel breast coil in the axial plane. The rationale behind this study is to show the feasibility of a radio-mics-powered model that could be integrated into the clinical practice by exploiting only standard-of-care DCE-MRI with the goal of reducing the required image pre-processing (ie, normalization and quantitative imaging map generation).Materials and Methods: 107 radiomic features were extracted from a …

Breast cancer Dynamic contrast-enhanced magnetic resonance imagingSupport Vector MachineComputer scienceNormalization (image processing)Breast NeoplasmsFeature selectionBreast cancerBreast cancerDiscriminative modelmedicineHumansRadiology Nuclear Medicine and imagingBreastRetrospective StudiesDynamic contrast-enhanced magnetic resonance imagingRadiomicsSupport vector machinesReceiver operating characteristicbusiness.industryPattern recognitionmedicine.diseaseMagnetic Resonance Imagingmachine learning Radiomics unsupervised feature selection Support vector machinesSupport vector machinemachine learningROC CurveFeature (computer vision)Test setFemaleArtificial intelligenceSettore MED/36 - Diagnostica Per Immagini E Radioterapiabusinessunsupervised feature selectionBreast cancer Dynamic contrast-enhanced magnetic resonance imaging; machine learning Radiomics unsupervised feature selection Support vector machinesAcademic Radiology
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Preparation of photocatalysts by physical methodologies

2021

The synthesis of photocatalytic materials is an important task for obtaining better results in terms of activity and/or selectivity in photocatalysis. This chapter reports an overview of the main methodologies using physical techniques to obtain bulky, supported powders or films and coatings to be used as heterogeneous photocatalysts. The classical chemical methodologies for the preparation of photocatalytic materials are presented in the previous chapter, so the information presented here complements the aforementioned one. Materials scientists and engineers have made significant progresses in the improvement of methods of synthesis of nanomaterial solids by developing different apparatuse…

Bulk and supported photocatalystsFlame synthesesChemical and physical vapor depositionPreparation of heterogeneous (photo)catalystsMechanochemistrySonochemistry
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Time to Deterioration in Quality of Life Score as a Modality of Longitudinal Analysis in Patients with Breast Cancer

2011

Abstract Purpose. This prospective multicenter study explored different definitions of time to deterioration (TTD) in quality of life (QoL) scores, according to different cutoffs of the minimal clinically important difference (MCID) as a modality for longitudinal QoL assessment in breast cancer patients. Methods. QoL was assessed using the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire C30 and BR-23 before surgery, after surgery, and 6 and 12 months later. The global health score, arm symptoms score (BRAS), and breast symptoms score were analyzed. For a given baseline score, QoL was considered to have deteriorated if this score decreased by ≥5 point…

Cancer Researchmedicine.medical_specialtyMultivariate analysisSentinel lymph node[SDV.CAN]Life Sciences [q-bio]/CancerBreast Neoplasms[ SDV.CAN ] Life Sciences [q-bio]/CancerCohort Studies03 medical and health sciences0302 clinical medicineBreast cancerQuality of lifeInternal medicinemedicineHumans030212 general & internal medicineLongitudinal StudiesProspective StudiesProspective cohort studyAgedNeoplasm StagingAged 80 and overbusiness.industryProportional hazards modelSentinel Lymph Node BiopsyMinimal clinically important differenceMiddle Agedmedicine.diseasehumanities3. Good healthSurgeryOncologySymptom Management and Supportive Care030220 oncology & carcinogenesisQuality of LifeLymph Node ExcisionFemalebusinessCohort study
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Good Quality Care for Cancer Patients Dying in Hospitals, but Information Needs Unmet: Bereaved Relatives’ Survey within Seven Countries

2021

Abstract Background Recognized disparities in quality of end‐of‐life care exist. Our aim was to assess the quality of care for patients dying from cancer, as perceived by bereaved relatives, within hospitals in seven European and South American countries. Materials and Methods A postbereavement survey was conducted by post, interview, or via tablet in Argentina, Brazil, Uruguay, U.K., Germany, Norway, and Poland. Next of kin to cancer patients were asked to complete the international version of the Care Of the Dying Evaluation (i‐CODE) questionnaire 6–8 weeks postbereavement. Primary outcomes were (a) how frequently the deceased patient was treated with dignity and respect, and (b) how well…

Cancer Researchmedicine.medical_specialtyPalliative careQuality managementNext of kinmedia_common.quotation_subject26Survey and questionnaireBereaved relatives03 medical and health sciencesDignity0302 clinical medicineGermanyNeoplasmsSurveys and QuestionnairesHealth caremedicineHumansFamily030212 general & internal medicinemedia_commonResponse rate (survey)Terminal Carebusiness.industryPalliative CareOdds ratioProxyHospitalsPeer reviewOncologySymptom Management and Supportive Care030220 oncology & carcinogenesisFamily medicineQuality of health carebusinessBrazilThe Oncologist
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Complete 1H and 13C NMR assignments of clerodane diterpenoids of Salvia splendens.

2006

Unambiguous and complete assignments of 1H and 13C NMR chemical shifts for five clerodane diterpenes, four of them isolated from Salvia splendens (salviarin, splendidin and splenolides A and B) and one obtained by acetylation of splenolide A, are presented. The assignments are based on 2D shift-correlated [1H,1H–COSY, 1H,13C-gHSQC–1J(C,H) and 1H,13C-gHMBC-nJ(C,H) (n = 2 and 3)] and nuclear Overhauser effect (NOE) experiments. The conformation of the rings of these compounds is supported by the 3J(H,H) values and NOE results. Copyright © 2006 John Wiley & Sons, Ltd.

Carbon IsotopesMagnetic Resonance SpectroscopybiologyStereochemistryChemistryChemical shiftAcetylationGeneral ChemistryNuclear Overhauser effectCarbon-13 NMRSalviabiology.organism_classificationDiterpenes ClerodaneUnambiguous and complete assignments of 1H and 13C NMR chemical shifts for five clerodane diterpenes four of them isolated from Salvia splendens (salviarin splendidin and splenolides A and B) and one obtained by acetylation of splenolide A are presented. The assignments are based on 2D shiftcorrelated [1H1H–COSY 1H13C-gHSQC–1J(CH) and 1H13C-gHMBC-nJ(CH) (n = 2 and 3)] and nuclear Overhauser effect (NOE) experiments. The conformation of the rings of these compounds is supported by the 3J(HH) values and NOE results. Copyright  2006 John Wiley & Sons LtdClerodane DiterpenesProton NMRGeneral Materials ScienceSalviaHydrogenMagnetic resonance in chemistry : MRC
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Impact of preclinical carotid atherosclerosis on global cardiovascular risk stratification and events in a 10-year follow-up: comparison between the …

2019

Background The aim of the study was to compare three widely used algorithms for stratification of the global cardiovascular risk (GCVR): the Framingham Heart Study (FHS) score, the European systemic coronary risk estimation (SCORE) and the Italian 'Progetto Cuore' (heart project) score. It was also investigated how preclinical carotid atherosclerosis (pre-ATS) might influence the incidence and improve the risk prediction of cerebrovascular and cardiovascular events. Methods Subjects (n = 358) without previous history of cardiovascular disease (CVD) were recruited and the GCVR was calculated for each patient. An ultrasound evaluation of the carotid arteries was also performed. Results Accord…

Carotid Artery DiseasesMaleTime Factorsintima-media thickening (IMT)Predictive Value of TestDisease030204 cardiovascular system & hematologyCarotid Intima-Media ThicknessDecision Support Technique0302 clinical medicineFramingham Heart StudyRisk FactorsProspective Studies030212 general & internal medicineProspective cohort studyasymptomatic carotid plaque (ACP)education.field_of_studyIncidence (epidemiology)IncidenceGeneral MedicineMiddle AgedPrognosisPlaque AtheroscleroticAlgorithmItalypreclinical carotid atherosclerosis (pre-ATS)Predictive value of testsCerebrovascular DisorderDisease ProgressionFemalemedicine.symptomRisk assessmentCardiology and Cardiovascular MedicineAlgorithmAlgorithmsHumanAdultTime FactorPrognosiPopulationglobal cardiovascular risk (GCVR)AsymptomaticRisk AssessmentDecision Support TechniquesFollow-Up Studie03 medical and health sciencesPredictive Value of TestsCarotid Intima-Media ThicknemedicineHumanseducationAgedAsymptomatic DiseaseCarotid Artery Diseasebusiness.industryRisk Factoralgorithms of cardiovascular riskCerebrovascular DisordersProspective StudieAsymptomatic DiseasesbusinessFollow-Up Studies
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Design of enzyme-mediated controlled release systems based on silica mesoporous supports capped with ester-glycol groups

2012

[EN] An ethylene glycol-capped hybrid material for the controlled release of molecules in the presence of esterase enzyme has been prepared. The final organic-inorganic hybrid solid S1 was synthesized by a two-step procedure. In the first step, the pores of an inorganic MCM-41 support (in the form of nanoparticles) were loaded with [Ru(bipy) 3]Cl 2 complex, and then, in the second step, the pore outlets were functionalized with ester glycol moieties that acted as molecular caps. In the absence of an enzyme, release of the complex from aqueous suspensions of S1 at pH 8.0 is inhibited due to the steric hindrance imposed by the bulky ester glycol moieties. Upon addition of esterase enzyme, del…

Cell viabilityINGENIERIA DE LA CONSTRUCCIONEthyleneRuthenium complexesMCM-41 supportsCytotoxicityGlycol derivativesEsteraseFunctionalizedOrganic-inorganic hybrid solidsGlycolschemistry.chemical_compoundQUIMICA ORGANICATumor Cells CulturedElectrochemistryControlled release systemsOrganic chemistryControlled releaseGeneral Materials ScienceSteric hindrancesMCF-7 cellsSpectroscopyHydrolysisEsterasesSilicaEstersSurfaces and InterfacesSilicon DioxideCondensed Matter PhysicsControlled releaseChlorine compoundsEster bondsBody fluidsHybrid materialsHybrid materialPorosityCell deathCell SurvivalSurface PropertiesCytotoxic drugsRutheniumHydrolysisEnzymatic hydrolysisEsterase enzymesPolymer chemistryHumansCamptothecin (CPT)Molecular capSize reductionsTherapeutic ApplicationEthylene glycolTwo-step procedureEsterificationSuspensions (fluids)Ruthenium compoundsQUIMICA INORGANICAMesoporous supportOligo(ethylene glycol)Cell internalizationMolecular gatesConfocal microscopychemistryEnzymatic hydrolysisEnzyme-mediated hydrolysisNanoparticlesCamptothecinCell cultureMesoporous materialAqueous suspensionsEthylene glycolHeLa Cells
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Pt–CeO thin film catalysts for PEMFC

2015

Abstract Platinum is the mostly used element in catalysts for fuel cell technology, but its high price limits large-scale applications. Platinum doped cerium oxide represents an alternative solution due to very low loading, typically few micrograms per 1 cm2, at the proton exchange membrane fuel cell (PEMFC) anode. High efficiency is achieved by using magnetron sputtering deposition of cerium oxide and Pt of 30 nm thick nanoporous films on large surface carbon nanoparticle substrates. Thin film techniques permits to grow the catalyst film characterized by highly dispersed platinum, mostly in ionic Pt2+ state. Such dispersed Pt species show high activity and stability. These new materials ma…

Cerium oxideMaterials scienceNanoporousCatalyst supportInorganic chemistryProton exchange membrane fuel cellchemistry.chemical_elementGeneral ChemistrySputter depositionCatalysisCatalysischemistryThin filmPlatinumCatalysis Today
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Scientometrics analysis of research activity and collaboration patterns in Chagas cardiomyopathy.

2018

Background Chagas cardiomyopathy is a serious and common complication of Chagas disease. Methods Through bibliometric and Social Network Analysis, we examined patterns of research on Chagas cardiomyopathy, identifying the main countries, authors, research clusters, and topics addressed; and measuring the contribution of different countries. Results We found 1932 documents on Chagas cardiomyopathy in the MEDLINE database. The most common document type was ‘journal article’, accounting for 79.6% of the total (n = 1538), followed by ‘review’ (n = 217, 11.2%). The number of published records increased from 156 in 1980–1984 to 311 in 2010–2014. Only 2.5% were clinical trials. Brazil and the USA …

Chagas diseaseChagas Cardiomyopathymedicine.medical_specialtyBoliviaLatin AmericansMyocarditislcsh:Arctic medicine. Tropical medicinelcsh:RC955-962MEDLINE030231 tropical medicineMEDLINECardiology030204 cardiovascular system & hematologyBibliometricsResearch and Analysis MethodsGeographical locations03 medical and health sciences0302 clinical medicineMedicine and Health SciencesParasitic DiseasesMedicineHumansChagas DiseaseCooperative BehaviorProtozoan Infectionsbusiness.industryResearchlcsh:Public aspects of medicinePublic Health Environmental and Occupational HealthSocial Supportlcsh:RA1-1270ScientometricsSouth AmericaResearch Assessmentmedicine.diseaseTropical DiseasesResearch PersonnelClinical trialInfectious DiseasesClinical researchBibliometricsFamily medicineCitation AnalysisPeople and placesbusinessCardiomyopathiesBrazilResearch ArticleNeglected Tropical DiseasesPLoS Neglected Tropical Diseases
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Individual behavior support in positive behavior support schools in Finland

2023

One objective in Finnish basic education is for pupils with disabilities or behavioral problems to be able to participate in mainstream education and ordinary classrooms. Positive behavior support (PBS) is an approach that offers multi-tiered behavior support for pupils. In addition to providing support at a universal level, educators need to have the necessary skills to provide more intensive individual support for pupils who need it. Check-in/Check-out (CICO) is a research-based individual support system that is widely used in PBS schools. The Finnish application of CICO includes an individual behavior assessment process for pupils with persistent challenging behaviors. In this article, w…

Check-in/Check-outoppiminenpositive behavior supportschool-based interventionoppilaatkäyttäytymishäiriöttukimuodotperusopetusPsychiatry and Mental healthtukeminenerityisopetusDevelopmental and Educational Psychologyneuropsychiatric disabilitykäyttäytyminenspecial educationInternational Journal of Developmental Disabilities
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