Search results for " systems"
showing 10 items of 9779 documents
Lipid Nanoparticles as Potential Gene Therapeutic Delivery Systems for Oral Administration.
2017
Background Gene therapy has experimented an increasing attention in the last decades, due to its enormous potential applications in the medical field. It can be defined as the use of genes or genetic material (DNA, RNA, oligonucleotides) to treat or prevent a disease state, generally a geneticbased one. Application Other applications, like treating viral, bacterial or parasite infections or development of vaccines are gaining also interest. Efficient gene therapy is mainly dependent on the ability of the highly labile genetic material to reach the therapeutic target. For this purpose, different delivery systems have been designed and extensively investigated. Nanoparticles offer a broad ran…
Molecular signatures of silencing suppression degeneracy from a complex RNA virus
2021
As genomic architectures become more complex, they begin to accumulate degenerate and redundant elements. However, analyses of the molecular mechanisms underlying these genetic architecture features remain scarce, especially in compact but sufficiently complex genomes. In the present study, we followed a proteomic approach together with a computational network analysis to reveal molecular signatures of protein function degeneracy from a plant virus (as virus-host protein-protein interactions). We employed affinity purification coupled to mass spectrometry to detect several host factors interacting with two proteins of Citrus tristeza virus (p20 and p25) that are known to function as RNA sil…
Whole genome sequencing data and de novo draft assemblies for 66 teleost species
2017
Teleost fishes comprise more than half of all vertebrate species, yet genomic data are only available for 0.2% of their diversity. Here, we present whole genome sequencing data for 66 new species of teleosts, vastly expanding the availability of genomic data for this important vertebrate group. We report on de novo assemblies based on low-coverage (9–39×) sequencing and present detailed methodology for all analyses. To facilitate further utilization of this data set, we present statistical analyses of the gene space completeness and verify the expected phylogenetic position of the sequenced genomes in a large mitogenomic context. We further present a nuclear marker set used for phylogenetic…
Take a Trip Through the Plant and Fungal Transportome of Mycorrhiza
2016
International audience; Soil nutrient acquisition and exchanges through symbiotic plant–fungus interactions in the rhizosphere are key features for the current agricultural and environmental challenges. Improved crop yield and plant mineral nutrition through a fungal symbiont has been widely described. In return, the host plant supplies carbon substrates to its fungal partner. We review here recent progress on molecular players of membrane transport involved in nutritional exchanges between mycorrhizal plants and fungi. We cover the transportome, from the transport proteins involved in sugar fluxes from plants towards fungi, to the uptake from the soil and exchange of nitrogen, phosphate, p…
Genome-Wide Profiling and Phylogenetic Analysis of the SWEET Sugar Transporter Gene Family in Walnut and Their Lack of Responsiveness to Xanthomonas …
2020
Following photosynthesis, sucrose is translocated to sink organs, where it provides the primary source of carbon and energy to sustain plant growth and development. Sugar transporters from the SWEET (sugar will eventually be exported transporter) family are rate-limiting factors that mediate sucrose transport across concentration gradients, sustain yields, and participate in reproductive development, plant senescence, stress responses, as well as support plant&ndash
El modelo cooperativo de sistemas agroalimentarios de innovación: el caso ANECOOP y el sistema citrícola valenciano
2015
English title: The cooperative model of agri-food innovation systems: ANECOOP and the Valencian citrus industry; International audience; Globalisation brings pressure on regional production systems to become regional production and innovation systems in order to maintain their competitiveness. However, the heterogeneity of the companies in these systems makes it difficult to respond to these challenges and obliges the response to be collective and mesoeconomic. To date, there has been a defence of the leadership of some private companies and other intermediaries such as business associations as vehicles of this process, but the part that cooperatives play in it has barely been studied. This…
A Knowledge-Based System as a Sustainable Software Application for the Supervision and Intelligent Control of an Alcoholic Fermentation Process
2020
One goal of specialists in food processing is to increase production efficiency in accordance with sustainability by optimising the consumption of raw food materials, water, and energy. One way to achieve this purpose is to develop new methods for process monitoring and control. In the winemaking industry, there is a lack of procedures regarding the common work based on knowledge acquisition and intelligent control. In the present article, we developed and tested a knowledge-based system for the alcoholic fermentation process of white winemaking while considering the main phases: the latent phase, exponential growth phase, and decay phase. The automatic control of the white wine&rsquo
A simple modelling of crop water balance for agrometeorological applications
1991
Abstract A simple agrometeorological model of crop water balance is presented. It aims at the best estimate possible of the water balance components with the simplest formulation and the minimum set of input data. The model works with a time step of one day and uses rainfall and the calculated evapotranspiration as the climatic inputs. Some soil and crop characteristics, such as the maximum available moisture and crop coefficients are required as input parameters. The model is tested using experimental data obtained on wheat and lucerne crops in the Paris region. The sensitivity of the model is discussed and some possible applications to rainfed crop management are presented.
Systems Approach to Eastern Baltic Coastal Zone Management
2020
Relying on the results of multivariate analysis of the re-analysis case studies from the BaltCoast project, specific features of integrated coastal management (ICM) approaches in Estonia, Latvia, Lithuania, and the Kaliningrad Oblast of the Russian Federation are highlighted in this paper. Eleven Eastern Baltic ICM case studies have been re-analyzed in-depth, which was the main focus of the present paper, covering a wide range of coastal landscapes, themes, policy issues, and ICM approaches. Five principal components explaining 84.86% of the total variance of ICM factor scores have been elicited by calculating rotation sums of squared loadings: (1) Stakeholder Involvement
Forest responses to last-millennium hydroclimate variability are governed by spatial variations in ecosystem sensitivity.
2020
Forecasts of forest responses to climate variability are governed by climate exposure and ecosystem sensitivity, but ecosystem model projections and process representations are under-constrained by data at multidecadal and longer timescales. Here, we assess ecosystem sensitivity to centennial-scale hydroclimate variability, by comparing dendroclimatic and pollen-inferred reconstructions of drought, forest composition and biomass for the last millennium with five ecosystem model simulations. In both observations and models, spatial patterns in ecosystem responses to hydroclimate variability are strongly governed by ecosystem sensitivity rather than climate exposure. Ecosystem sensitivity was…