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showing 10 items of 7948 documents

Effect of Cardiorespiratory Fitness on Risk of Sudden Cardiac Death in Overweight/Obese Men Aged 42 to 60 Years

2018

The purpose of this study was to examine the subject and combined associations of cardiorespiratory fitness (fitness) and body mass index (BMI) with the risk of sudden cardiac death (SCD) in middle-aged men. This prospective study was based on a population sample of 2,357 men aged 42 to 60 years, who were followed up in the Kuopio Ischemic Heart Disease cohort study. Fitness was directly measured by peak oxygen uptake (VO2peak) during progressive exercise testing to volitional fatigue. Participants were divided into 4 groups (fit-normal weight, unfit-normal weight, fit-overweight/obese, and unfit-overweight/obese) based on the median values of fitness and BMI. A total of 253 (10.7%) SCDs oc…

AdultMaleRiskmedicine.medical_specialtyobesityPopulationsudden deathheart failurecardiac arrest030204 cardiovascular system & hematologyOverweightLower risksydämen vajaatoimintasudden cardiac deathBody Mass Index03 medical and health sciences0302 clinical medicineSurveys and QuestionnairesInternal medicineFitnessHumansMedicineProspective Studies030212 general & internal medicineäkkikuolemaeducationFinlandeducation.field_of_studycardiorespiratory fitnessbusiness.industryHazard ratioVO2 maxCardiorespiratory fitnessta3141ta3142Middle AgedOverweightfatnessDeath Sudden CardiacExercise TestCardiologylihavuussydämenpysähdysmedicine.symptomCardiology and Cardiovascular MedicinebusinessBody mass indexCohort studyAmerican Journal of Cardiology
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Leukocyte count, diabetes mellitus and age are strong predictors of stroke in a rural population in southern Italy: an 8-year follow-up.

2001

Stroke incidence rates in the Mediterranean area are higher compared to northern European countries. In this study, we present the 8-year prospective data from a small rural Sicilian town. This population, consisting of 1351 subjects (622 males and 729 females), is homogeneous for ethnic background with traditional healthy dietary habits and shows low cholesterol mean levels. We found that the risk of stroke was significantly associated with the record of at least one previous neurological symptom (PNS), such as lack of strength, loss of vision or speech or possible drop attacks, and high hematocrit in males, and to high body mass index (BMI) and waist-hip ratio (WHR), diabetes, hypertensio…

AdultMaleRural Populationmedicine.medical_specialtySettore MED/09 - Medicina InternaEpidemiologyPopulationEthnic groupDiabetes ComplicationsLeukocyte CountPredictive Value of TestsDiabetes mellitusEpidemiologymedicineHumansRisk factoreducationStrokeeducation.field_of_studybusiness.industryPublic healthAge FactorsLeukocyteMiddle AgedCerebrovascular disordermedicine.diseaseSurgeryStrokeItalyFemaleRisk factorRural areaCardiology and Cardiovascular MedicinebusinessDemographyFollow-Up StudiesAtherosclerosis
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3D-printing-assisted fabrication of chitosan scaffolds from different sources and cross-linkers for dental tissue engineering

2021

The aim of the present study was to fabricate and characterise chitosan scaffolds from animal and fungal sources, with or without gelatine as a co-polymer, and cross-linked to 3-glycidyloxyproply trimethoxysilane (GPTMS) or genipin for application in dental root tissue engineering. Chitosan-based scaffolds were prepared by the emulsion freeze-drying technique. Scanning electron microscopy (SEM) and nano-focus computed tomography (nano-CT) were used to characterise scaffold microstructure. Chemical composition and cross-linking were evaluated by Fourier transform infrared-attenuated total reflectance spectroscopy. Compression tests were performed to evaluate scaffold mechanical properties. S…

AdultMaleScaffoldMaterials scienceRD1-811AdolescentCompressive StrengthScanning electron microscopeSimulated body fluid0206 medical engineeringBiocompatible MaterialsDiseases of the musculoskeletal system02 engineering and technologyApatiteChitosanYoung Adultchemistry.chemical_compoundTissue engineeringfungal chitosanDental pulp stem cellsMaterials TestingHumansIridoidsCells CulturedDental PulpChitosanTissue EngineeringTissue ScaffoldsStem Cellstechnology industry and agricultureSilanes020601 biomedical engineeringdental pulp stem cellsRC925-935chemistryvisual_artPrinting Three-Dimensionalvisual_art.visual_art_mediumGenipinSurgeryFemalePorosityBiomedical engineeringEuropean Cells and Materials
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Schizophrenia and automatic processing: an exploratory study.

1991

This study deals with the schizophrenic deficit as one of automatic processing. To test the idea, a special experimental task was designed on which 21 schizophrenics, 21 depressives, and 21 normal subjects had to complete a series of simple geometric figures. When the subjects had thoroughly learned this activity, another information source, a brief story, was introduced, and the subjects had to pay attention to the story while they did the task. Two dependent variables were considered, execution time and performance. There were no differences among the three groups in the first experimental condition; but in the second condition, when the distractor was introduced, schizophrenics needed m…

AdultMaleSchizophrenia (object-oriented programming)Exploratory researchExperimental and Cognitive PsychologyNeuropsychological Tests050105 experimental psychologyDevelopmental psychologyTask (project management)03 medical and health sciences0302 clinical medicineSchizophrenic PsychologymedicineReaction TimeHumans0501 psychology and cognitive sciencesAttentionDepressive Disorder05 social sciencesCognitive disorderInformation processingCognitionmedicine.diseaseSensory Systems030227 psychiatryPattern Recognition VisualPattern recognition (psychology)Mental RecallSchizophreniaSchizophrenic PsychologyPsychologyPsychomotor PerformanceCognitive psychologyPerceptual and motor skills
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Dopamine D2/D3 receptor availability and venturesomeness.

2011

The construct of impulsivity is considered as a major trait of personality. There is growing evidence that the mesolimbic dopamine system plays an important role in the modulation of impulsivity and venturesomeness, the two key components within the impulsivity-construct. The aim of the present study was to explore an association between trait impulsivity measured with self-assessment and the dopaminergic neurotransmission as measured by positron emission tomography (PET) in a cohort of healthy male subjects. In vivo D2/D3 receptor availability was determined with [(18)F]fallypride PET in 18 non-smoking healthy subjects. The character trait impulsivity was measured using the Impulsiveness-V…

AdultMaleSelf-AssessmentPyrrolidinesStatistics as TopicNeuroscience (miscellaneous)Neuropsychological TestsImpulsivityStatistical parametric mappingPersonality AssessmentBrain mappingDevelopmental psychologyCohort StudiesYoung AdultRisk-TakingDopamine receptor D3Dopamine receptor D2Surveys and QuestionnairesmedicineHumansRadiology Nuclear Medicine and imagingTemporal cortexBrain MappingReceptors Dopamine D2BrainPsychiatry and Mental healthFallypridePositron-Emission TomographyBenzamidesImpulsive Behaviormedicine.symptomPersonality Assessment InventoryPsychologyNeurosciencePsychiatry research
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Associations between self-estimated and measured physical fitness among 40-year-old men and women

2005

The aim was to evaluate whether 40-year-old men and women are able to estimate their level of fitness compared with actual measured physical fitness. Twenty-nine men and 35 women first completed a questionnaire at home and then their physical fitness was measured at laboratory. The index of self-estimated physical fitness was calculated by summing up the scores of self-estimated endurance, strength, speed and flexibility. The index of self-estimated endurance was calculated by summing up the scores of self-estimated endurance and those of the self-estimated distance they could run, cycle, ski and walk. The index of measured physical fitness was calculated by summing up the z-scores of a sub…

AdultMaleSelf-Assessmentmedicine.medical_specialtyPhysical fitnessPhysical Therapy Sports Therapy and RehabilitationWalkingmedicine.disease_causeRunning03 medical and health sciencesOxygen Consumption0302 clinical medicineJumpingSkiingSurveys and QuestionnairesHand strengthmedicineHumansOrthopedics and Sports Medicine030212 general & internal medicineGroup levelMathematicsAnalysis of VarianceHand Strengthbusiness.industryVO2 max030229 sport sciencesBicyclingTest (assessment)ROC CurvePhysical FitnessExercise TestPhysical EndurancePhysical therapyJumpFemaleAnalysis of variancebusinessDemographyScandinavian Journal of Medicine and Science in Sports
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Recovery of hormonal, blood lipid, and hematological profiles from a North Pole expedition.

2011

INTRODUCTION This study examined the recovery patterns of hormonal, blood lipid, and hematological profiles following strenuous physical loading, continuous extreme cold exposure and energy deficit induced by a North Pole expedition. METHODS Seven men completed an 850-km North Pole expedition in temperatures varying from -3 degrees C to -47 degrees C. Daily energy intake was approximately 23 MJ x d(-1) and was composed of approximately 60% fat. Blood samples were collected 2 wk before (Pre) the expedition and after 2 wk (Post 1), and 2 mo (Post 2). Additional samples were collected on the first (R1), third (R3), and fifth (R5) return days. RESULTS Mean weight loss upon return was 10 kg. Ene…

AdultMaleSerummedicine.medical_specialtyGlobulinBlood lipidsHematocritWeight lossStress PhysiologicalInternal medicinemedicineHumansExerciseTestosteroneHematologic Testsmedicine.diagnostic_testbiologyArctic RegionsPublic Health Environmental and Occupational HealthCold ClimateLipidsCold TemperatureEndocrinologybiology.proteinHemoglobinmedicine.symptomEnergy MetabolismHormoneLipoproteinAviation, space, and environmental medicine
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Autologous whole blood injections to patients with chronic urticaria and a positive autologous serum skin test: a placebo-controlled trial.

2005

<i>Background:</i> Patients with chronic urticaria (CU) frequently exhibit positive skin test reactions to autologous serum (ASST). Therapies aimed at inducing tolerance to circulating histamine-releasing factors in ASST+ CU patients, e.g. by treatment with autologous whole blood (AWB), have not yet been tested. <i>Objective:</i> To test whether ASST+ CU patients can benefit from repeated low-dose intramuscular injections of AWB. <i>Methods:</i> We characterized CU severity and duration, anti-Fc<sub>Ε</sub>RI and anti-IgE expression, use of antihistamines, and quality of life in 56 CU patients (ASST+: 35, ASST–: 21) and assessed the t…

AdultMaleSerummedicine.medical_specialtyUrticariaImmunoblottingPlacebo-controlled studyEnzyme-Linked Immunosorbent AssayDermatologymedicine.disease_causePlaceboGastroenterologyAutoimmunityAutohemotherapyBlood Transfusion AutologousInternal medicinemedicineHumansSingle-Blind MethodProspective StudiesChronic urticariaWhole bloodSkin Testsbusiness.industryReceptors IgEImmunoglobulin EMiddle AgedSurgeryAntibodies Anti-IdiotypicClinical trialTreatment OutcomePatient SatisfactionChronic DiseaseQuality of LifeAutologous serum skin testFemalebusinessFollow-Up StudiesDermatology (Basel, Switzerland)
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Who are maximizers? Future oriented and highly numerate individuals

2014

Two studies investigated cognitive mechanisms that may be associated with people's tendency to maximize. Maximizers are individuals who are spending a great amount of effort in order to find the very best option in a decision situation, rather than stopping the decision process when they encounter a satisfying option. These studies show that maximizers are more future oriented than other people, which may motivate them to invest the extra energy into optimal choices. Maximizers also have higher numerical skills, possibly facilitating the cognitive processes involved with decision trade-offs.

AdultMaleSettore M-PSI/01 - Psicologia GeneraleCognitionDecision Makingmaximizing numeracy time perspective decision makingHumansFemaleNeuropsychological TestsChoice BehaviorProblem Solving
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Molecular epidemiology of tuberculosis in Sicily, Italy: what has changed after a decade?

2014

Background We aimed to investigate the molecular epidemiology of Mycobacterium tuberculosis complex (MTBC) isolates in the province of Palermo, Sicily, Italy, by characterizing 183 isolates identified in the years 2004-2012. A comparison with 104 MTBC strains identified in the same geographic area in the years 1994-2000 was also carried out. Methods One hundred eighty-three MTBC isolates identified in Palermo, Italy, in the years 2004-2012 were analyzed by spoligotyping and the 24 mycobacterial interspersed repetitive unit (MIRU)-variable-number tandem-repeat (VNTR) method typing. Susceptibility testing to streptomycin, isoniazid, rifampin and ethambutol was also performed. Furthermore, the…

AdultMaleSettore MED/07 - Microbiologia E Microbiologia ClinicaVeterinary medicineTuberculosis Sicily Epidemiology Spoligotyping MIRU-VNTRTuberculosisGenotypeEpidemiologyLineage (evolution)Microbial Sensitivity TestsMinisatellite RepeatsSettore MED/42 - Igiene Generale E ApplicataMIRU-VNTRDrug Resistance BacterialIsoniazidMedicineTuberculosisHumansTypingSicilyAntibiotics AntitubercularEthambutolSpoligotypingMolecular EpidemiologyMolecular epidemiologybiologybusiness.industryMycobacterium tuberculosisMiddle Agedmedicine.diseasebiology.organism_classificationMolecular TypingInfectious DiseasesParasitologyMycobacterium tuberculosis complexStreptomycinFemaleRifampinbusinessEthambutolmedicine.drugResearch ArticleBMC Infectious Diseases
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