Search results for " tools"
showing 10 items of 331 documents
The pre-appropriation of controlling tools : the role of the enabling management
2022
The appropriation of controlling tools is a theme that has been widely addressed research in management over the last twenty years (De Vaujany, 2005, 2006; Carton et al., 2006; Grimand, 2006, 2012, Quemener and Fimbel, 2012; Bessire et al., 2012; Bédé et al., 2012; Bernard, 2019, Couleau-Dupont, 2010, ...). This research has mobilised various theoretical frameworks and methodologies. Some mobilise the theory of appropriation proposed by De Vaujany (2005), some others use theoretical frameworks from other disciplines, such as legitimacy (Suchman, 1995), regulation theory (Reynaud, 1979) or even neo-institutional theory (Di Maggio and Powell, 1991). The literature does not propose a single fr…
Antiproliferative Activity Predictor: A New Reliable In Silico Tool for Drug Response Prediction against NCI60 Panel.
2022
In vitro antiproliferative assays still represent one of the most important tools in the anticancer drug discovery field, especially to gain insights into the mechanisms of action of anticancer small molecules. The NCI-DTP (National Cancer Institute Developmental Therapeutics Program) undoubtedly represents the most famous project aimed at rapidly testing thousands of compounds against multiple tumor cell lines (NCI60). The large amount of biological data stored in the National Cancer Institute (NCI) database and many other databases has led researchers in the fields of computational biology and medicinal chemistry to develop tools to predict the anticancer properties of new agents in advan…
Condition Monitoring Technologies for Synthetic Fiber Ropes - a Review
2020
This paper presents a review of different condition monitoring technologies for fiber ropes. Specifically, it presents an overview of the articles and patents on the subject, ranging from the early 70’s up until today with the state of the art. Experimental results are also included and discussed in a conditionmonitoring context,where failuremechanisms and changes in physical parameters give improved insight into the degradation process of fiber ropes. From this review, it is found that automatic width measurement has received surprisingly little attention, and might be a future direction for the development of a continuous condition monitoring system for synthetic fiber ropes.
Active learning in a real-world bioengineering problem: A pilot-study on ophthalmologic data processing
2019
Active learning is a format alternative to the conventional lecture/recitation/laboratory; research results have reported that it is suitable to encourage student inquiry and foster peer mentoring. Although the availability of computer-based learning materials in biomedical sciences is increasing, there are relatively few studies aimed to integrate traditional methods of teaching with inquiry-based approaches utilizing these Information and Communication Technologies (ICT) tools. This paper describes a pilot-study on a comprehensive active laboratory course about digital ophthalmologic signal classification, experienced by a group of undergraduates in Bio-Electronic Engineering. During the …
Architecture in the digital age. Evolution of language and contemporary design.
2012
The ‘computer revolution’ is the most obvious phenomenon of our time. The new capabilities introduced by the digital drafting have triggered a substantial evolution of the relationship between representation and design. The diffusion of digital technologies in Architecture has opened new frontiers in the design field, stimulating the development of a new expressive language that promotes generating complex shapes. On the other hand, the shape often becomes the main interest of the designers. Then, is the project only a formal question? Are the glamour images become the main target to which the ‘New Architecture’ aims?
New imaging techniques and opportunities in endoscopy.
2011
Gastrointestinal endoscopy is undergoing major improvements, which are driven by new available technologies and substantial refinements of optical features. In this Review, we summarize available and evolving imaging technologies that could influence the clinical algorithm of endoscopic diagnosis. Detection, characterization and confirmation are essential steps required for proper endoscopic diagnosis. Optical and nonoptical methods can help to improve each step; these improvements are likely to increase the detection rate of neoplasias and reduce unnecessary endoscopic treatments. Furthermore, functional and molecular imaging are emerging as new diagnostic tools that could provide an oppor…
Methods to investigate coronary microvascular function in clinical practice.
2012
A growing amount of data is increasingly showing the relevance of coronary microvascular dysfunction (CMVD) in several clinical contexts. This article reviews techniques and clinical investigations of the main noninvasive and invasive methods proposed to study coronary microcirculation and to identify CMVD in the presence of normal coronary arteries, also trying to provide indications for their application in clinical practice.
Are tools all we need? Digital Humanities in the time of its institutionalisation
2011
Three key features of the Digital Humanities today are its quantitative growth, its institutionalisation and its definition as a discipline. In the first part of this article (2. Institutional models) I shall pinpoint some models of institutionalisation that are emerging in the international scenario. Against this background, I shall then discuss (3. Tools) some concepts central to Digital Humanities’ self-definition, such as those of practice, ‘building’, centre, project, product and tools, particularly questioning the opinion that the creation of friendly digital tools is the key issue in the future of the field. I shall finally suggest that ‘instrumentalism’, ‘project fever’ and an exces…
Universal Design of Information Sharing Tools for Disaster Risk Reduction
2019
International audience; Disaster information sharing tools are an important aspect of disaster resilience, and it is of utmost importance that these tools are accessible and usable for as many potential users as possible. In this paper, we evaluate the accessibility of a selection of tools for crowdsourcing disaster situation information. As our evaluation shows that the selected tools are not fully accessible, we provide recommendations for mitigation, as well as highlight the importance of further research in this area.
Sequencing, De Novo Assembly and Annotation of the Colorado Potato Beetle, Leptinotarsa decemlineata, Transcriptome
2012
Background. The Colorado potato beetle (Leptinotarsa decemlineata) is a major pest and a serious threat to potato cultivation throughout the northern hemisphere. Despite its high importance for invasion biology, phenology and pest management, little is known about L. decemlineata from a genomic perspective. We subjected European L. decemlineata adult and larval transcriptome samples to 454-FLX massively-parallel DNA sequencing to characterize a basal set of genes from this species. We created a combined assembly of the adult and larval datasets including the publicly available midgut larval Roche 454 reads and provided basic annotation. We were particularly interested in diapause-specific g…