Search results for " trauma"

showing 10 items of 384 documents

Xenon improves long-term cognitive function, reduces neuronal loss and chronic neuroinflammation, and improves survival after traumatic brain injury …

2019

Background.Xenon is a noble gas with neuroprotective properties. We previously showed that xenon improves short and long-term outcomes in young adult mice after controlled cortical impact (CCI). This is a follow-up study investigating xenon’s effect on very long-term outcome and survival. Methods.C57BL/6N (n=72) young adult male mice received single CCI or sham surgery and were treated with either xenon (75%Xe:25%O2) or control gas (75% N2:25%O2). The outcomes used were: 1) 24-hour lesion volume and neurological outcome score; 2)contextual fear-conditioning at 2 weeks and 20 months; 3) corpus callosum white matter quantification; 4) immunohistological assessment of neuroinflammation and neu…

MaleXenonhippocampusnerve degenerationCorpus callosumBUPRENORPHINEneuroinflammationMice0302 clinical medicineCognition030202 anesthesiologyAnesthesiologyBrain Injuries TraumaticMedicineEPIDEMIOLOGYYoung adultmemory disordersNeuronstraumatic brain injurySham surgeryBrain3. Good healthD-ASPARTATE RECEPTORmedicine.anatomical_structureNeuroprotective AgentsAnesthesianeuroprotectionmedicine.symptomLife Sciences & BiomedicineTraumatic brain injuryHYPOPITUITARISMNeuroprotectionWhite matter03 medical and health sciencesANALGESIAINHALED XENONAnimalsgeneral anaesthesiaSurvival analysisHYPOTHERMIAInflammationScience & Technologybusiness.industry1103 Clinical SciencesHypothermiamedicine.diseaseCOMPETITIVE-INHIBITIONSurvival AnalysisMice Inbred C57BLPATHOLOGYDisease Models AnimalAnesthesiology and Pain MedicineChronic DiseasebusinessCognition Disorders030217 neurology & neurosurgeryWHITE-MATTER DAMAGEFollow-Up StudiesBritish journal of anaesthesia
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Estimating Exposome Score for Schizophrenia Using Predictive Modeling Approach in Two Independent Samples: The Results From the EUGEI Study

2019

The EUGEI project was supported by the grant agreement HEALTH-F2-2010-241909 from the European Community’s Seventh Framework Programme. The authors are grateful to the patients and their families for participating in the project. They also thank all research personnel involved in the GROUP project, in particular J. van Baaren, E. Veermans, G. Driessen, T. Driesen, E. van’t Hag and J. de Nijs. Bart PF Rutten was funded by a VIDI award number 91718336 from the Netherlands Scientific Organisation.

MalecannabisLogistic regression0302 clinical medicineLasso (statistics)Adverse Childhood ExperiencesStatisticsOdds RatioChild AbusePOLYGENIC RISKpsychosisChildPsychiatrySUMMER BIRTHFramingham Risk Score3. Good healthExposomePsychiatry and Mental healthmachine learningSchizophreniaArea Under CurveFemaleMarijuana UseSeasonsEnvironment And Schizophrenia—Feature Editor: Jim van OsLife Sciences & Biomedicineenvironmentpredictive modelingAdultExposomeDISORDERSrisk scoreYoung Adult03 medical and health sciencesPSYCHOSISmedicineJournal ArticleHumansHearing LossMETAANALYSISDEFICIT SCHIZOPHRENIAENVIRONMENTModels StatisticalScience & Technologychildhood traumaReceiver operating characteristicbusiness.industrySiblingsBullyingBayes TheoremChild Abuse SexualOdds ratiohearing impairmentmedicine.disease030227 psychiatryschizophreniaLogistic ModelsROC CurveSexual abuseCase-Control StudiesbusinessCHILDHOOD ADVERSITIES030217 neurology & neurosurgerywinter birth
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Traumatic fascicular neuroma

1988

A 72-year-old man had developed amiodarone neuropathy. He was found, at biopsy, to have a fascicular neuroma of his right sural nerve, unassociated with his underlying neuropathy, apparently due to blunt trauma, as electroneurographic needling of this nerve could safely be ruled out by the patient and his physicians. Such fascicular neuromas, which may remain without sensory deficits, may develop at an unknown frequency, and may only be uncovered by biopsy — or autopsy — in a coincidental neuropathic process.

Malemedicine.medical_specialtyAutopsySural nerveAmiodaronePathology and Forensic MedicineNeuromaCellular and Molecular NeuroscienceSural NerveBiopsyotorhinolaryngologic diseasesmedicineHumansAgedDry needlingSpinal Neoplasmsmedicine.diagnostic_testbusiness.industryNeuromamedicine.diseaseSurgeryMicroscopy ElectronSpinal Nervesmedicine.anatomical_structureBlunt traumaNeurology (clinical)Perineuriumbusinessmedicine.drugActa Neuropathologica
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Effects of systemically transplanted allogeneic bone marrow multipotent mesenchymal stromal cells on rats' recovery after experimental polytrauma.

2013

Background The aim of this study was to evaluate impact of transplantation of bone marrow mesenchymal stromal cells (BM MMSCs) on recovery after polytrauma and bone fracture repair. Methods A total 27 Wistar-Kyoto rats were divided into three groups (n = 9): normal control (A), polytrauma (B), and polytrauma treated with BM MMSC transplantation (C). The experimental polytrauma model was made on male rats by causing multiple fractures and hemorrhagic shock. At 36 hours 9 days after surgery, nine rats received allogeneic BM MMSCs (1 × 10(6) cells per kilogram) intravenously. The day before operation and at Days 3 and 10 after surgery as well as at the end of the experiment, blood analysis was…

Malemedicine.medical_specialtyCallus formationUrologyHematocritCritical Care and Intensive Care MedicineMesenchymal Stem Cell TransplantationRats Inbred WKYmedicineAnimalsTransplantation HomologousBony CallusCells CulturedBone Marrow TransplantationWound Healingmedicine.diagnostic_testbusiness.industryMultiple TraumaMesenchymal stem cellCell DifferentiationMesenchymal Stem CellsBone fractureRecovery of Functionmedicine.diseasePolytraumaRatsTransplantationRed blood cellDisease Models Animalmedicine.anatomical_structureTreatment OutcomeSurgeryBone marrowbusinessFollow-Up StudiesThe journal of trauma and acute care surgery
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Progress of instability in fragility fractures of the pelvis: An observational study.

2019

Abstract Fragility fractures of the pelvis (FFP) are an increasing entity among elderly persons. Characteristics are different from high-energy pelvic trauma. Little is known about the natural course of FFP in conservative and after operative treatment. Materials and methods Medical charts and radiologic data of 148 patients with an FFP, who were admitted in a 3-year period, were analysed retrospectively. Incidence and characteristics of fracture progression (FP) were noted. Results Patients presenting early after a traumatic event had more often non-displaced fractures, fractures with lower FFP Type classification and were more frequently treated conservatively. FP was observed in 21 cases…

Malemedicine.medical_specialtyConservative Treatment03 medical and health sciencesFracture Fixation Internal0302 clinical medicineElderly personsMedicineHumansPelvic BonesFracture typePelvisGeneral Environmental ScienceAgedRetrospective Studies030222 orthopedicsNatural courseBone Density Conservation Agentsbusiness.industryIncidence (epidemiology)030208 emergency & critical care medicineMiddle AgedSurgeryPelvic traumamedicine.anatomical_structureTreatment OutcomeGeneral Earth and Planetary SciencesObservational studyFemalebusinessTomography X-Ray ComputedOperative fixationOsteoporotic FracturesInjury
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Sports-related injuries in elderly men still active in sports.

1994

By means of a questionnaire with a complementary interview and physical examination, the site and nature of sports injuries were investigated over a 10-year period (1977-1987) in 97 elderly athletes (age range 70-81 years). The athletes were still active in training and competition with a mean competition background of 15 years. Of the subjects studied 30 were strength/power athletes and the remaining 67 endurance athletes. Altogether we found 273 sports-related injuries (169 acute and 104 overuse injuries). Of the injuries 75% had occurred in the lower extremities. The most commonly injured part of the body was the knee (20% of all cases). Sprains of the thigh and knee were the most freque…

Malemedicine.medical_specialtyCumulative Trauma DisordersPoison controlPhysical Therapy Sports Therapy and RehabilitationPhysical examinationKnee InjuriesThighSuicide preventionOccupational safety and healthOxygen ConsumptionPhysical medicine and rehabilitationSkiingInjury preventionmedicineHumansOrthopedics and Sports MedicineAnkle InjuriesFoot InjuriesFinlandAgedAged 80 and overmedicine.diagnostic_testbiologyAthletesbusiness.industryMusclesTrack and FieldHuman factors and ergonomicsGeneral Medicinebiology.organism_classificationmedicine.anatomical_structureAthletic InjuriesPhysical EnduranceSprains and StrainsPhysical therapyAccidental FallsJointsbusinesshuman activitiesSportsResearch ArticleBritish Journal of Sports Medicine
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Management of nasal septal abscess in childhood: our experience.

2004

Summary A nasal septal abscess is usually the result of an infected hematoma of the septum. A secondary septal abscess may be the result of infections extending from any of the neighbouring tissues. The necrosis of septal cartilage may lead to nasal deformities and severe impairment of nasal patency and growth. Objectives: Assess if the drainage of the abscess and the immediate reconstruction of the destroyed nasal septum in the acute phase is the best treatment to prevent short- and long-term effect on nasal and midface growth. Methods: Three pediatric patients treated with drainage and immediate implantation of homologous bank cartilage prior to 1990 and four treated with mosaic plastic u…

Malemedicine.medical_specialtyFeverNoseHemostaticsSeptum absceFormaldehydeNasal trauma; Septum abscess; Surgical treatmentNasal traumaotorhinolaryngologic diseasesmedicineNasal septumNasal septal abscessHumansTransplantation HomologousAbscessFibrin glueChildNasal SeptumSurgical treatmentbusiness.industryCartilageInfected hematomaGeneral Medicinemedicine.diseaseAbscessSurgerymedicine.anatomical_structureCartilageEpistaxisTreatment OutcomeOtorhinolaryngologyChild PreschoolPolyvinyl AlcoholPediatrics Perinatology and Child HealthInfected haematomaDrainageFemaleNasal ObstructionbusinessComplicationInternational journal of pediatric otorhinolaryngology
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Serum Sex Hormone–Binding Globulin and Cortisol Concentrations are Associated With Overreaching During Strenuous Military Training

2010

The purpose was (a) to study the effect of an 8-week Finnish military basic training period (BT) on physical fitness, body composition, mood state, and serum biochemical parameters among new conscripts; (b) to determine the incidence of overreaching (OR); and (c) to evaluate whether initial levels or training responses differ between OR and noOR subjects. Fifty-seven males (19.7 ± 0.3 years) were evaluated before and during BT. Overreaching subjects had to fulfill 3 of 5 criteria: decreased aerobic physical fitness (VO2max), increased rating of perceived exertion (RPE) in 45-minute submaximal test at 70% of VO2max or sick absence from these tests, increased somatic or emotional symptoms of …

Malemedicine.medical_specialtyHydrocortisoneCumulative Trauma DisordersPhysical ExertionPhysical fitnessPhysical Therapy Sports Therapy and RehabilitationYoung AdultOxygen ConsumptionSex hormone-binding globulinHeart RateSex Hormone-Binding GlobulinInternal medicineHeart ratemedicineHumansTestosteroneOrthopedics and Sports MedicineLactic AcidInsulin-Like Growth Factor Ita315TestosteroneHydrocortisoneRating of perceived exertionbiologybusiness.industryOvertrainingGeneral MedicineOverreachingmedicine.diseaseAffectMilitary PersonnelEndocrinologyPhysical FitnessBody CompositionPhysical Endurancebiology.proteinbusinessPsychologymedicine.drugJournal of Strength and Conditioning Research
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Value and limits of computer-assisted tomography.

1980

Three years ago, at the VIIth International Congress of Radiology in Otorhinolaryngology, held in Copenhagen, the early impressive results of computer-assisted tomography (CAT) in otorhinolaryngology were presented. Since considerable technologic and diagnostic progress of CAT has taken place in the meantime, questions about the increase in CAT's value and the expansion of its limits are appropriate now. Computed and, in some cases, conventional tomograms of facial lesions are used in the discussion of these questions. There is no doubt of CAT's advance within the last few years; there are, however, limits of CAT to be emphasized: (a) coronal CAT might be uncomfortable (especially if the ga…

Malemedicine.medical_specialtyIntracranial tumorSkull NeoplasmsComputer assisted tomographyFacial BonesInternational congressMedicineCraniocerebral TraumaHumansNeck stiffnessAgedbusiness.industryHead injurymedicine.diseaseCervical spineOtorhinolaryngologyOtorhinolaryngologySpinal InjuriesCoronal planeFemaleRadiologyFacial NeoplasmsbusinessNuclear medicineTomography X-Ray ComputedHeadneck surgery
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Traumatic dental injuries among schoolchildren in Valencia, Spain.

2010

Aim: The aim of the present study was to identify some factors related to the occurrence of dental trauma in mixed and permanent dentition. Design of the study: Over a period of two months 1325, 6 to 18 year olds from three primary schools in Valencia were examined. Data was collected through clinical examinations and interviews and their Dental trauma was classified according to IADT´s criteria. Results: The prevalence of dental injuries was 6%; boys aged between 12-18 years old experienced more injuries than girls. There was a statistical difference between the types of fractures. Non complicated coronal fractures were the most frequent (9.18%). Games were the main cause of trauma (40%) i…

Malemedicine.medical_specialtyPediatricsAdolescentPermanent dentitionStatistical differencePoison controlSuicide preventionOccupational safety and healthInjury preventionmedicinePrevalenceHumansChildGeneral DentistryDental traumabusiness.industryHuman factors and ergonomicsTooth Injuriesmedicine.disease:CIENCIAS MÉDICAS [UNESCO]stomatognathic diseasesOtorhinolaryngologySpainUNESCO::CIENCIAS MÉDICASPhysical therapySurgeryFemalebusinessMedicina oral, patologia oral y cirugia bucal
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