Search results for " venous"

showing 10 items of 212 documents

Estimated Glomerular Filtration Rate Is an Easy Predictor of Venous Thromboembolism in Cancer Patients Undergoing Platinum-Based Chemotherapy

2014

Abstract Background. Reduced estimated glomerular filtration rate (eGFR) has been associated with increased venous thromboembolism (VTE) risk in the general population. VTE incidence significantly increases in cancer patients, especially those undergoing chemotherapy. Despite the evidence that a substantial number of cancer patients have unrecognized renal impairment, as indicated by reduced eGFR in the presence of serum creatinine levels within the reference value, chemotherapy dosage is routinely adjusted for serum creatinine values. Among chemotherapies, platinum-based regimens are associated with the highest rates of VTE. A cohort study was designed to assess the value of pretreatment e…

MaleOncologyCancer ResearchSettore MED/06 - Oncologia Medicamedicine.medical_treatmentPlatinum CompoundsPlatinum-based chemotherapy; Renal impairment; Risk prediction; Risk stratification; Toxicity; Venous thromboembolism; Adult; Aged; Aged 80 and over; Antineoplastic Agents; Cohort Studies; Creatinine; Female; Glomerular Filtration Rate; Humans; Kidney; Male; Middle Aged; Neoplasms; Platinum Compounds; Venous Thromboembolism; Young Adult; Cancer Research; Oncology; Medicine (all)Platinum CompoundKidneyAntineoplastic AgentCohort Studieschemistry.chemical_compoundNeoplasmsRenal impairmentPlatinum-based chemotherapyAged 80 and overeducation.field_of_studyMedicine (all)Hazard ratioVenous ThromboembolismMiddle AgedRisk predictionOncologySymptom Management and Supportive CareCreatinineCohortFemaleHumanGlomerular Filtration RateCohort studyAdultmedicine.medical_specialtyPopulationRenal functionAntineoplastic AgentsYoung AdultInternal medicinemedicineHumanscardiovascular diseaseseducationRisk stratificationAgedChemotherapyCreatinineToxicitybusiness.industryCancerRenal impairment; Risk stratification; Venous thromboembolism; Risk prediction; Toxicity; Platinum-based chemotherapymedicine.diseaseSurgerychemistryNeoplasmCohort StudiebusinessThe Oncologist
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Problem-based learning for anesthesia resident operating room crisis management training.

2018

Background Senior anesthesia residents must acquire competency in crisis management for operating room (OR) emergencies. We conducted problem based learning (PBL) OR emergency scenarios for anesthesia residents, focused on emergencies in ‘Airway’, ‘Circulation’, ‘Central venous catheter’, and ‘Pain management complications’. Non-technical skills are an integral component of team-based OR emergency management. Methods Prior to integrated OR emergency clinical and non-technical skills PBL training, participating 35 anesthesia residents completed two 5-point scale surveys regarding frequency of emergency experiences in the operating room, and self-confidence for anesthesia-related crisis manag…

MaleOperating RoomsCritical Care and Emergency Medicinemedicine.medical_treatmentSocial SciencesCrew resource managementlcsh:MedicineCrisis managementLearning and Memory0302 clinical medicineAnesthesiology030202 anesthesiologyMedicine and Health SciencesCardiac ArrestPsychologyIntubationAnesthesia030212 general & internal medicinelcsh:ScienceMultidisciplinaryEmergency managementPharmaceuticsSimulation and ModelingProblem-based learningScale (social sciences)AnesthesiaEngineering and TechnologyFemaleClinical CompetenceCentral venous catheterResearch ArticleBiotechnologyCatheterseducationCardiologyBioengineeringSurgical and Invasive Medical ProceduresResearch and Analysis Methods03 medical and health sciencesDrug TherapymedicineLearningPain ManagementHumansbusiness.industryCrew Resource Management Healthcarelcsh:RCognitive PsychologyBiology and Life SciencesInternship and ResidencyProblem-Based LearningSelf ConceptCognitive ScienceMedical Devices and Equipmentlcsh:QIntubationbusinessAirwayNeurosciencePLoS ONE
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Effect of a surveillance system for decreasing neonatal nosocomial infections.

2018

Nosocomial infection in very low birthweight (VLBW) infants is a common complication with high morbimortality. New strategies to reduce its occurrence have recently led to the development of neonatal surveillance programs.To determine whether the NeoKissEs surveillance system implementation in our neonatal unit has been associated with a decrease in nosocomial infection in VLBW infants, as well as a reduction in the use of antibiotics and central venous catheters (CVC).Retrospective and descriptive study of infants1500 g admitted between January 2011 and December 2017. Rates of use of antibiotics and CVC were calculated, as well as late-onset sepsis incidence. Data were compared before and …

MalePediatricsmedicine.medical_specialtyVlbw infantsmedicine.drug_classAntibioticsBreastfeeding03 medical and health sciences0302 clinical medicine030225 pediatricsNosocomial sepsisIntensive Care Units NeonatalSepsisMedicineCentral Venous CathetersHumansInfant Very Low Birth WeightRetrospective StudiesCross InfectionInfection ControlNeonatal sepsisbusiness.industryInfant NewbornObstetrics and Gynecologymedicine.diseaseAnti-Bacterial AgentsBreast FeedingSpainPediatrics Perinatology and Child HealthFemalebusinessComplication030217 neurology & neurosurgeryEarly human development
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Correlation between chronic prostatitis syndrome and pelvic venous disease: a survey of 2,554 urologic outpatients.

2000

Objectives: In this study we evaluated the association between chronic prostatitis syndrome (CPS), varicocele and hemorrhoids as manifestations of a pelvic venous disease. Methods: Our retrospective study was based upon 2554 patients treated in two general urology clinics over the past 10 years. We have assessed the incidence of CPS among urological patients. Results: We found 483 patients with CPS, representing 18.9% of the total number of visits at the outpatient clinic. In this group the percentage of varicocele and hemorrhoids was 14.69 and 8.48%, whereas in a control group these figures were 5.02 and 5.84%, respectively (p < 0.001 and 0.1054). Such a difference is statistically sign…

MalePelvic venous diseaseUrologyData CollectionIncidenceChronic prostatitis syndromeComorbiditySyndromeHemorrhoidsSettore MED/24 - UrologiaPelvisProstatitisProstatitiItalyReference ValuesCase-Control StudiesChronic DiseaseOutpatientsVaricoceleHumansHemorrhoidRetrospective StudiesEuropean urology
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Chronic Prostatitis and Prostatodynia: Ultrasonographic Alterations of the Prostate, Bladder Neck, Seminal Vesicles and Periprostatic Venous Plexus

1988

Transrectal ultrasonography was performed in 121 patients with the chronic prostatitis syndrome (CPS), and in 20 patients with urological pathology not involving the prostate gland. The ultrasonographic aspects of the seminal vesicles (SV) in normal subjects and in patients with the CPS are described. In the latter group, characteristic ultrasonographic patterns can often be obtained, even in patients affected by prostatodynia, in whom all the other clinical and laboratory findings were absent. They consisted of: (a) dyshomogeneous echo-structure of the prostate; (b) constant dilatation of the periprostatic venous plexus, greater than 150 mm2; (c) dilated, elongated SV, with thickening of t…

MaleProstatic Diseasesmedicine.medical_specialtyPeriprostatic venous plexusmedicine.diagnostic_testbusiness.industryUrologyVesicleUrinary BladderProstateUrologySeminal VesiclesProstatitismedicine.diseaseProstatitisMuscle hypertrophyNeck of urinary bladdermedicine.anatomical_structureProstatemedicineHumansTransrectal ultrasonographyIn patientbusinessUltrasonographyEuropean Urology
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Effect of Haemodynamic Changes on Epithelium-related Intestinal Injury in Off-pump Coronary Surgery

2014

Intestinal injury is thought to play a central role in the occurrence of multiorgan dysfunction after on-pump coronary surgery. Clinical benefits of off-pump revascularisation remain, however, controversial.Hepatic enzymes and plasmatic IL-6, IL-8 and intestinal-type fatty acid binding protein (I-FABP) were determined in 20 patients (age 65-75) undergoing either on-pump (n = 10) or off-pump (n = 10) coronary surgery. Haemodynamic and biochemical parameters, catecholamine and volume therapy were monitored.Central venous pressure (CVP) was significantly higher in the off-pump group during and 12h after operation (9.5 ± 1.35 vs. 6.21 ± 0.63 mmH2O, p = 0.012). Higher GGT and GLDH levels occurre…

MalePulmonary and Respiratory Medicinemedicine.medical_specialtyEnterocyteMedizinCoronary Artery Bypass Off-PumpHemodynamicsInflammationFatty Acid-Binding ProteinsGastroenterologyIntestinal mucosaInternal medicinemedicineHumansIntestinal MucosaGamma-glutamyltransferaseInterleukin 6AgedbiologyInterleukin-6business.industryInterleukin-8HemodynamicsCentral venous pressuregamma-GlutamyltransferaseIntestinal Diseasesmedicine.anatomical_structureAnesthesiaCatecholaminebiology.proteinFemalemedicine.symptomCardiology and Cardiovascular Medicinebusinessmedicine.drugHeart, Lung and Circulation
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Anti-Inflammatory Treatment with Standardized Human Serum Protein Solution Reduces Local and Systemic Inflammatory Response after Hemorrhagic Shock

2005

<i>Objective:</i> Reperfusion after hemorrhagic shock leads to local and systemic inflammatory response. This study evaluates the effect of a short-term treatment with standardized human serum protein solution (SPS) on the local and systemic inflammatory response in the mesenteric microcirculation in the rat. <i>Methods:</i> Spontaneously breathing animals underwent median laparotomy and exteriorization of an ileal loop for intravital microscopy of the mesenteric microcirculation. Volume-controlled hemorrhagic shock was set by arterial blood withdrawal (2.5 ml/100 g body weight for 60 min), followed by reperfusion for 4 h. SPS (n = 10) or saline 0.9% (controls, n = 1…

MaleResuscitationCentral Venous PressureInflammatory responseAnti-Inflammatory AgentsHemodynamicsBlood PressureInflammationShock HemorrhagicMicrocirculationRats Sprague-DawleyHeart RateLeukocytesAnimalsMedicinebusiness.industryMicrocirculationHemodynamicsBlood ProteinsBlood proteinsRatsBlood pressureShock (circulatory)ImmunologySurgeryBlood Gas Analysismedicine.symptombusinessEuropean Surgical Research
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Dabigatran after Short Heparin Anticoagulation for Acute Intermediate-Risk Pulmonary Embolism: Rationale and Design of the Single-Arm PEITHO-2 Study

2017

AbstractPatients with intermediate-risk pulmonary embolism (PE) may, depending on the method and cut-off values used for definition, account for up to 60% of all patients with PE and have an 8% or higher risk of short-term adverse outcome. Although four non-vitamin K-dependent direct oral anticoagulants (NOACs) have been approved for the treatment of venous thromboembolism, their safety and efficacy as well as the optimal anticoagulation regimen using these drugs have not been systematically investigated in intermediate-risk PE. Moreover, it remains unknown how many patients with intermediate-high-risk and intermediate-low-risk PE were included in most of the phase III NOAC trials. The ongo…

MaleRiskmedicine.medical_specialtypulmonary embolismDrug-Related Side Effects and Adverse Reactionsmedicine.medical_treatmentHemorrhageintermediate risk030204 cardiovascular system & hematologyDabigatran03 medical and health sciencesYoung Adult0302 clinical medicineRecurrenceInternal medicineGermanymedicineHumansdabigatran030212 general & internal medicineProspective StudiesProspective cohort studySurvival analysisvenous thromboembolism recurrencebusiness.industryHeparinAnticoagulantsHematologyThrombolysisHeparinReference Standardsmedicine.diseaseThrombosisSurvival Analysis3. Good healthPulmonary embolismright ventricular functionRegimenTreatment OutcomeResearch Designmajor bleedingAcute Diseasedabigatran; intermediate risk; major bleeding; pulmonary embolism; right ventricular function; venous thromboembolism recurrenceFemalebusinessmedicine.drugFollow-Up Studies
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Bernard-Horner Syndrome after accidental lesion of carotid artery: case report

2012

Among the complications of internal jugular vein insertion there is the lesion of the cervical sympathetic trunk with the onset of Bernard-Horner syndrome, consisting of miosis, eyelid ptosis, enophthalmos and anhidrosis on the same side of the lesion. The neurological damage can be caused by the direct puncture of the trunk or by the irritating and compressive action of a hematoma during the puncture of the internal jugular; the clinical picture, when reversible, resolves in a few months. The case we report is about the onset of the syndrome after accidental puncture of carotid artery, followed by the total disappearance of signs in a few days.

MaleSettore MED/18 - Chirurgia GeneraleHorner SyndromeBernard-Horner syndrome central venous catheterizationHumansSettore MED/41 - AnestesiologiaMiddle AgedCarotid Artery Injuries
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Prophylaxis of venous thromboembolism in elderly patients with multimorbidity

2013

none 327 si Pharmacological thromboprophylaxis (TP) is known to reduce venous thromboembolism (VTE) in medical inpatients, but the criteria for risk-driven prescription, safety and impact on mortality are still debated. We analyze data on elderly patients with multimorbidities admitted in the year 2010 to the Italian internal medicine wards participating in the REPOSI registry to investigate the rate of TP during the hospital stay, and analyze the factors that are related to its prescription. Multivariate logistic regression, area under the ROC curve and CART analysis were performed to look for independent predictors of TP prescription. Association between TP and VTE, bleeding and death in …

MaleTVPSettore MED/09 - Medicina InternaComorbidityLogistic regressionFondaparinuxVENOUS THROMBOEMBOLISM; THROMBOPROPHYLAXIS; Medical PatientsMedical patients; Thromboprophylaxis; Venous thromboembolism; Aged; Aged 80 and over; Area Under Curve; Comorbidity; Female; Hospital Mortality; Hospitalization; Humans; Logistic Models; Male; Propensity Score; Venous Thromboembolism; Internal Medicine; Emergency MedicineThromboprophylaxis Venous thromboembolism Medical patients80 and overHospital MortalityAged 80 and overSettore MED/45 - Scienze Infermieristiche Generali Cliniche E PediatricheMedical patients; Thromboprophylaxis; Venous thromboembolism; Aged; Aged; 80 and over; Area Under Curve; Comorbidity; Female; Hospital Mortality; Hospitalization; Humans; Logistic Models; Male; Propensity Score; Venous Thromboembolism; Internal Medicine; Emergency Medicineprophylaxis; venous thromboembolism; elderlyHospitalizationArea Under CurveEmergency MedicineFemaleprophylaxismedicine.drugVenous thromboembolismmedicine.medical_specialtyThromboprophylaxis; Venous thromboembolismmultimorbidityBarthel indexvenous thromboembolismMEDLINEMedical patients; Thromboprophylaxis; Venous thromboembolism; Aged; Aged 80 and over; Area Under Curve; Comorbidity; Female; Hospital Mortality; Hospitalization; Humans; Logistic Models; Male; Propensity Score; Venous Thromboembolism; Emergency Medicine; Internal Medicineelderly patientselderlyMedical patientsInternal medicineInternal MedicinemedicineHumansMedical prescriptionprophylaxis; venous thromboembolism; elderly patientsPropensity ScoreIntensive care medicineThromboprophylaxisAgedbusiness.industryprophylaxiMedical patients; Thromboprophylaxis; Venous thromboembolismprophylaxis; Venous thromboembolism; Elderly; multimorbidity; medical patients; thromboprophylaxismedicine.diseaseComorbidityLogistic ModelsPropensity score matchingbusinessVenous thromboembolism
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