Search results for " visceral"
showing 10 items of 68 documents
Visceral leishmaniasis in a patient with Down syndrome
2006
TLR4 abrogates the Th1 immune response through IRF1 and IFN-β to prevent immunopathology during L. infantum infection
2020
A striking feature of human visceral leishmaniasis (VL) is chronic inflammation in the spleen and liver, and VL patients present increased production levels of multiple inflammatory mediators, which contribute to tissue damage and disease severity. Here, we combined an experimental model with the transcriptional profile of human VL to demonstrate that the TLR4-IFN-β pathway regulates the chronic inflammatory process and is associated with the asymptomatic form of the disease. Tlr4-deficient mice harbored fewer parasites in their spleen and liver than wild-type mice. TLR4 deficiency enhanced the Th1 immune response against the parasite, which was correlated with an increased activation of de…
Halo Sign and Eosinophilia: What Is Your Diagnosis?
2018
Blood eosinophilia associated with transient and migrating nodules with a halo sign on chest computed tomography scan should suggest larva migrans related to toxocariasis or <i>ascaris suum</i>.
Obesità e rischio cardiovascolare.
2007
L’obesità rappresenta attualmente la più diffusa patologia da malnutrizione delle Società occidentali industrializzate e si associa spesso a svariate complicanze invalidanti sia mediche che chirurgiche. Essa è, inoltre, una condizione ad elevata prevalenza ed in continuo e costante incremento, al punto da essere etichettata come una “Epidemia globale”. Nella presente review sono stati analizzati i risultati degli studi più recenti che hanno individuato nella patologia del tessuto adiposo uno dei meccanismi più importanti nello sviluppo dell’aterosclerosi e delle manifestazioni cliniche ad essa connesse. Particolare riguardo è stato dato, oltre che alle evidenze epidemiologiche riguardanti i…
Hypoadiponectinemia: A Link between Visceral Obesity and Metabolic Syndrome
2012
Metabolic syndrome (MetS) represents a combination of cardiometabolic risk factors, including visceral obesity, glucose intolerance or type 2 diabetes, elevated triglycerides, reduced HDL cholesterol, and hypertension. MetS is rapidly increasing in prevalence worldwide as a consequence of the “epidemic” obesity, with a considerable impact on the global incidence of cardiovascular disease and type 2 diabetes. At present, there is a growing interest on the role of visceral fat accumulation in the occurrence of MetS. In this review, the effects of adipocytokines and other proinflammatory factors produced by fat accumulation on the occurrence of the MetS have been also emphasized. Accordingly, …
Arteriopatie viscerali
2022
Le malattie delle arterie viscerali e renali sono sempre di più frequente osservazione per il chirurgo vascolare. Il progressivo invecchiamento della popolazione e il costante progresso tecnologico, in particolare della diagnostica per immagini, sicuramente hanno contribuito a un più frequente riscontro di queste patologie. Per quanto riguarda la patogenesi, la malattia aterosclerotica è la causa più frequente per entrambi i distretti arteriosi analizzati. I recenti progressi delle procedure endovascolari hanno ulteriormente migliorato la prognosi di queste malattie arteriose permettendo di trattare patologie complesse con procedure sempre meno invasive, e la conoscenza di queste moderne te…
Disfunzione del tessuto adiposo e diabete mellito tipo 2: scarsa utilità diagnostica della quantificazione del grasso tramite RMN.
2014
Leishmania tarentolae and Leishmania infantum in humans, dogs and cats in the Pelagie archipelago, southern Italy.
2021
Visceral leishmaniasis (VL) caused by Leishmania infantum is endemic in the Mediterranean basin with most of the infected human patients remaining asymptomatic. Recently, the saurian-associated Leishmania tarentolae was detected in human blood donors and in sheltered dogs. The circulation of L. infantum and L. tarentolae was investigated in humans, dogs and cats living in the Pelagie islands (Sicily, Italy) by multiple serological and molecular testing. Human serum samples (n = 346) were tested to assess the exposure to L. infantum by immunofluorescence antibody test (IFAT), enzyme-linked immunosorbent assay (ELISA) and Western blot (WB) and to L. tarentolae by IFAT. Meanwhile, sera from do…
Serum miRNAs in women affected by hyperandrogenic polycystic ovary syndrome: the potential role of miR-155 as a biomarker for monitoring the estropro…
2018
MicroRNAs can be used as very efficient circulating biomarkers. The role of microRNAs in polycystic ovary syndrome (PCOS) and the effects of antiandrogen therapy on microRNA expression is still not fully understood. A panel of serum microRNAs were retrotranscribed via looped reverse primer transcription specific for each miRNA and quantified via probe specific RT-PCR in 16 Caucasian hyperandrogenic PCOS women selected according to the Rotterdam criteria and in a subset of seven patients after four months of sequential reverse antiandrogenic therapy. All women recruited underwent an oral glucose tolerance test (OGTT) and a baseline total cholesterol, high density lipoproteins cholesterol, tr…
Cirugía en el carcinoma broncogénico no microcítico en estadio I con diámetro ≤ de 3 cm. Factores pronósticos clínico-patológicos
2013
Los datos crecientes de incidencia y prevalencia del cáncer de pulmón (CP) lo convierten, actualmente, en la primera causa de muerte por cáncer, tanto en el hombre como en la mujer, estando ampliamente demostrada su relación etiológica con el hábito tabáquico. Tiene un mal pronóstico y unos resultados terapéuticos muy pobres, con unas expectativas de supervivencia a 5 años muy bajas, que en los datos más favorables no supera el 15% del total de casos nuevos diagnosticados. Estos hechos han condicionado, durante muchos años, un gran esfuerzo por parte de las distintas sociedades científicas en la elaboración de formas de clasificación o de agrupación de los pacientes, con el fin de homogenei…