Search results for " years"
showing 10 items of 147 documents
The Effect of Migraine Prophylaxis on Migraine-Related Resource Use and Productivity
2009
In the US, it is estimated that up to 10% of men and 25% of women, particularly those aged 25-55 years, experience debilitating migraines, such that the condition presents an enormous economic burden for patients, health systems, employers and society. Migraine headache is a particularly prevalent condition associated with major reductions in patients' quality of life. From a payer perspective, the implementation of relevant programmes of migraine prophylaxis is highly desirable. Consistent evidence exists, from several randomized, controlled studies, of the efficacy of amitriptyline, divalproex sodium, propranolol, timolol and topiramate in migraine prophylaxis. Considering resource utiliz…
Large-scale epidemiological data on vascular disorders of the intestine
2020
Objectives: This article aims to provide updates on the worldwide epidemiology of vascular disorders of the intestine.Methods: A comprehensive search for obtaining worldwide epidemiologic informati...
Economic evaluation of prolonged and enhanced ECG Holter monitoring in acute ischemic stroke patients
2019
Objective: Atrial fibrillation (AF) is a major cause for recurrent stroke, has severe impact on a patient's health and imposes a high economic burden for society. Current guidelines recommend 24 h ECG monitoring (standard-of-care, SoC) to detect AF after stroke to reduce the risk of future events. However, paroxysmal AF (PAF) is difficult to detect within this period as it occurs infrequently and unpredictably. In a randomized controlled trial (Find-AF(RANDOMISED)), prolonged and enhanced Holter ECG monitoring (EPM) revealed a significantly higher detection rate of AF compared to SoC, although its cost-effectiveness has not yet been investigated. Methods: Based on the data of FIND-AF(RANDOM…
Cost-effectiveness analysis of patent foramen ovale closure with Amplatzer plus medical therapy compared to medical therapy in patients with a histor…
2021
Abstract Background A patent foramen ovale (PFO) is formed when the ovale foramen does not close spontaneously or re-opens leaving the right and left atrium connected. The present study was conducted to analyze the cost-effectiveness of PFO closure with Amplatzer device plus medical therapy (MT) compared to MT alone in the French reimbursement system for PFO patients with a prior history of stroke, using the RESPECT study data. Methods A multi-state Markov model was used. The analysis was conducted from a collective perspective over a 10-year time horizon with 4% discount applied for costs and health effects. The simulated population included adult patients with PFO. Sub-group analysis was …
Women’s empowerment and child mortality: the case of Bangladesh
2018
Pasaku izmantošanas iespējas 4 - 5 gadus vecu bērnu uzvedības uzlabošanai
2017
Diplomdarba “Pasaku izmantošanas iespējas 4 – 5 gadus vecu bērnu uzvedības uzlabošanai” mērķis ir izpētīt pasaku izmantošanas iespējas 4 – 5 gadus vecu bērnu uzvedības problēmu mazināšanā. Darba teorētiskā daļa satur informāciju par pētījuma problemātiku, empīriskā daļa atspoguļo sākotnējo uzvedības problēmu biežumu grupā X un pasaku ietekmi uz bērniem, atklājot pasaku izmantošanas iespējas. Pētījuma uzdevumi ir: analizēt teorētisko literatūru par pētījuma problemātiku; analizēt bērnu literatūru un radīt pasakas, kas atstātu pozitīvu iespaidu uz bērnu uzvedību; veikt empīrisku pētījumu par pasaku izmantošanas iespējām 4 – 5 gadus vecu bērnu uzvedības problēmu mazināšanā. Izvirzītā hipotēze …
Mathematical problem-solving in early school years with Bee-bot
2018
Los entornos relacionados con la robótica y los lenguajes visuales de programación por bloques permiten plantear tareas que pueden ser entendidas como problemas con contenido matemático aptos para edades escolares tempranas. Estos entornos permiten proponer situaciones problemáticas en edades en las que el formalismo o el escaso conocimiento matemático impide a los estudiantes abordar problemas matemáticos más complejos. En este trabajo se da cuenta de cómo el robot programable Bee-bot constituye un dispositivo privilegiado donde poder observar cómo los estudiantes toman decisiones durante el proceso de resolución. The environments related to robotics and the visual block-based programming …
The Translation Scene in Latvia (Latvian SSR) during the Stalinist Years
2018
[full article, abstract in English; abstract in Lithuanian] In this paper the author continues to explore the translation scene in 20th century Latvia (Veisbergs 2016a). The period under discussion covers 1945–1953, the years of Stalin’s rule after WWII until his death in 1953. The translation situation is described by discussing nationalisation and centralisation of publishers, book liquidation, censorship, ideologisation and politicisation, russification, Latvian émigré translations and other aspects of importance in an attempt to present the translation scene of the period from different angles. At the end of the article an extensive list of references is provided that can serve as an in…
Parenting Stress in Families of Children with Autism Spectrum Disorder and ADHD
2015
The purpose of this study was to compare the parenting stress experienced by parents of 121 children from 5 to 9 years old with autism spectrum disorder (ASD), attention deficit/hyperactivity disorder (ADHD), comorbid ASD+ADHD, and typical development in different domains related to child and parent characteristics using the Parenting Stress Index. The three clinical groups presented greater perceived parenting stress than did the comparison group (CG). The ADHD group obtained higher levels of parenting stress related to attachment and depression than did the other groups. The ASD+ADHD group presented a unique profile of differences from the CG on Health and Spouse subscales. Results highl…
Estimates, trends, and drivers of the global burden of type 2 diabetes attributable to PM2·5 air pollution, 1990–2019: an analysis of data from the G…
2022
Background: Experimental and epidemiological studies indicate an association between exposure to particulate matter (PM) air pollution and increased risk of type 2 diabetes. In view of the high and increasing prevalence of diabetes, we aimed to quantify the burden of type 2 diabetes attributable to PM2·5 originating from ambient and household air pollution.Methods: We systematically compiled all relevant cohort and case-control studies assessing the effect of exposure to household and ambient fine particulate matter (PM2·5) air pollution on type 2 diabetes incidence and mortality. We derived an exposure–response curve from the extracted relative risk estimates using the MR-BRT (meta-regress…