6533b857fe1ef96bd12b4589
RESEARCH PRODUCT
Estimates, trends, and drivers of the global burden of type 2 diabetes attributable to PM2·5 air pollution, 1990–2019: an analysis of data from the Global Burden of Disease Study 2019
Katrin BurkartKate CauseyAaron J. CohenSarah S. WozniakDevashri Digvijay SalviCristiana AbbafatiVictor AdekanmbiJose C. AdsuarKeivan AhmadiFares AlahdabZiyad Al-alyVahid AlipourNelson Alvis-guzmanAdeladza Kofi AmegahCatalina Liliana AndreiTudorel AndreiFereshteh AnsariJalal ArablooOlatunde AremuTimur AripovEbrahim BabaeeMaciej BanachAnthony BarnettTill Winfried BärnighausenNeeraj BediMasoud BehzadifarYannick BéjotDerrick A. BennettIsabela M. BensenorRobert S. BernsteinKrittika BhattacharyyaAli BijaniAntonio BiondiSomayeh BohlouliSusanne BreitnerHermann BrennerZahid A. ButtLuis Alberto CámeraCarlos Cantu-britoFelix CarvalhoEster CerinVijay Kumar ChattuBal Govind ChauhanJee-young Jasmine ChoiDinh-toi ChuXiaochen DaiLalit DandonaRakhi DandonaAhmad DaryaniKairat DavletovBarbora De CourtenFeleke Mekonnen DemekeEdgar Denova-gutiérrezSamath Dhamminda DharmaratneMeghnath DhimalDaniel DiazShirin DjalaliniaBruce B. DuncanMaysaa El Sayed ZakiSharareh EskandariehMohammad FareedFarshad FarzadfarNazir FattahiMehdi FazlzadehEduarda FernandesIrina FilipFlorian FischerNataliya A. FoigtMarisa FreitasAhmad GhashghaeeParamjit GillIbrahim Abdelmageed GinawiSameer Vali GopalaniYuming GuoRajat Das GuptaTesfa Dejenie HabtewoldRandah R. HamadehSamer HamidiGraeme J. HankeyEdris HasanpoorHamid Yimam HassenSimon I. HayBehzad HeibatiMichael K. HoleNaznin HossainMowafa HousehSeyed Sina Naghibi IrvaniJalil JaafariMihajlo JakovljevicRavi Prakash JhaJost B. JonasJacek Jerzy JozwiakAmir KasaeianNeda KaydiYousef Saleh KhaderMorteza Abdullatif KhafaieEjaz Ahmad KhanJunaid KhanMd Nuruzzaman KhanKhaled KhatabAmir M. KhaterYun Jin KimRuth W. KimokotiAdnan KisaMika KivimäkiLuke D. KnibbsSoewarta KosenParvaiz A. KoulAi KoyanagiBarthelemy Kuate DefoNuworza KugbeyPaolo LauriolaPaul H. LeeMostafa LeiliSonia LewyckaShanshan LiLee Ling LimShai LinnYong LiuStefan LorkowskiPhetole Walter MahashaNarayan B. MahotraAzeem MajeedAfshin MalekiReza MalekzadehAbdullah A. MamunNavid ManafiSanti MartiniBirhanu Geta MeharieRitesh G. MenezesTomislav MestrovicBartosz MiazgowskiTomasz MiazgowskiTed R. MillerG. K. MiniAndreea MiricaErkin M. MirrakhimovBahram MohajerShafiu MohammedViswanathan MohanAli H. MokdadLorenzo MonastaPaula MoragaShane Douglas MorrisonUlrich Otto MuellerSatinath MukhopadhyayGhulam MustafaSaravanan MuthupandianGurudatta NaikVinay NangiaDuduzile Edith NdwandweRuxandra Irina NegoiDina Nur Anggraini NingrumJean Jacques NoubiapFelix Akpojene OgboAndrew T OlagunjuObinna E. OnwujekweAlberto OrtizMayowa O. OwolabiMahesh P ASonghomitra Panda-jonasEun-kee ParkFatemeh Pashazadeh KanMeghdad PirsahebMaarten J. PostmaHadi PourjafarAmir RadfarAlireza RafieiFakher RahimVafa Rahimi-movagharMuhammad Aziz RahmanRajesh Kumar RaiChhabi Lal RanabhatSamira RaoofiLal RawalAndre M. N. RenzahoAziz RezapourDaniela RibeiroLeonardo RoeverLuca RonfaniSiamak SabourBasema SaddikEhsan SadeghiSahar Saeedi MoghaddamAmirhossein SahebkarMohammad Ali SahraianHamideh SalimzadehSundeep Santosh SalviAbdallah M. SamyJuan SanabriaRodrigo Sarmiento-suárezThirunavukkarasu SathishMaria Inês SchmidtAletta Elisabeth SchutteSadaf G. SepanlouMasood Ali ShaikhKiomars SharafiAziz SheikhMika ShigematsuRahman ShiriReza ShirkoohiKerem ShuvalIreneous N. SoyiriRafael Tabarés-seisdedosYonatal Mesfin TeferaArash Tehrani-banihashemiMohamad-hani TemsahKavumpurathu Raman ThankappanRoman Topor-madryLorainne Tudor CarIrfan UllahMarco VacantePascual R. ValdezTommi Juhani VasankariFrancesco S. ViolanteYasir WaheedCharles D. A. WolfeTomohide YamadaNaohiro YonemotoChuanhua YuSojib Bin ZamanYunquan ZhangSanjay ZodpeyStephen S. LimJeffrey D. StanawayMichael BrauerHash(0x5651c97b2c90)subject
Contaminación del AireHealth (social science)Type II DiabetesType 2 diabetes deathsair pollutionand YLLs attributable to all PM2·5 air pollutionMedicine (miscellaneous)and change from 1990 to 2019DALYsburden of diseaseGlobal Burden of DiseaseCarga Global de EnfermedadesMELLITUSINFLAMMATIONand household PM2·5 pollution from solid fuels in seven GBD super-regions and globally in 2019Diabetes MellitusHumansBiologyASSOCIATIONSRISKINSULIN-RESISTANCEGBD 2019 Diabetes and Air Pollution CollaboratorsHealth PolicyMaterial ParticuladoPublic Health Environmental and Occupational HealthBayes TheoremLONG-TERM EXPOSUREHumanosYLDsChemistryDiabetes Mellitus Type 23121 General medicine internal medicine and other clinical medicineAños de Vida Ajustados por Calidad de Vidaambient PM2·5 pollutionParticulate MatterQuality-Adjusted Life YearsHuman medicineFINE PARTICULATE MATTERRAType II Diabetes; air pollution; burden of disease;description
Background: Experimental and epidemiological studies indicate an association between exposure to particulate matter (PM) air pollution and increased risk of type 2 diabetes. In view of the high and increasing prevalence of diabetes, we aimed to quantify the burden of type 2 diabetes attributable to PM2·5 originating from ambient and household air pollution.Methods: We systematically compiled all relevant cohort and case-control studies assessing the effect of exposure to household and ambient fine particulate matter (PM2·5) air pollution on type 2 diabetes incidence and mortality. We derived an exposure–response curve from the extracted relative risk estimates using the MR-BRT (meta-regression—Bayesian, regularised, trimmed) tool. The estimated curve was linked to ambient and household PM2·5 exposures from the Global Burden of Diseases, Injuries, and Risk Factors Study 2019, and estimates of the attributable burden (population attributable fractions and rates per 100 000 population of deaths and disability-adjusted life-years) for 204 countries from 1990 to 2019 were calculated. We also assessed the role of changes in exposure, population size, age, and type 2 diabetes incidence in the observed trend in PM2·5-attributable type 2 diabetes burden. All estimates are presented with 95% uncertainty intervals.Findings: In 2019, approximately a fifth of the global burden of type 2 diabetes was attributable to PM2·5 exposure, with an estimated 3·78 (95% uncertainty interval 2·68–4·83) deaths per 100 000 population and 167 (117–223) disability-adjusted life-years (DALYs) per 100 000 population. Approximately 13·4% (9·49–17·5) of deaths and 13·6% (9·73–17·9) of DALYs due to type 2 diabetes were contributed by ambient PM2·5, and 6·50% (4·22–9·53) of deaths and 5·92% (3·81–8·64) of DALYs by household air pollution. High burdens, in terms of numbers as well as rates, were estimated in Asia, sub-Saharan Africa, and South America. Since 1990, the attributable burden has increased by 50%, driven largely by population growth and ageing. Globally, the impact of reductions in household air pollution was largely offset by increased ambient PM2·5.Interpretation: Air pollution is a major risk factor for diabetes. We estimated that about a fifth of the global burden of type 2 diabetes is attributable PM2·5 pollution. Air pollution mitigation therefore might have an essential role in reducing the global disease burden resulting from type 2 diabetes.Funding: Bill & Melinda Gates Foundation.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2022-07-01 | The Lancet Planetary Health |