Search results for "Épidémiologie"
showing 10 items of 271 documents
Intérêt des méthodes alternatives dans l’évaluation du médicament dans les populations particulières
2020
Well conducted randomized clinical trial is considered gold standard in drug safety and efficacy evaluation. Drug development can be challenging in rare diseases, or in ethically sensitive populations (pregnant women, children, patient with cognitive defect), because of low number of subjects. The low rate of observed events at a sample scale in this population can lead to a biased evaluation of drugs compared to the general population. The aim of this work was to address alternative methods for drug evaluation in particular populations, especially pharmaco-epidemiology on populational database of the SNDS (Système National des Données de Santé). We first evaluate the safety of anti-TNFα in…
The association between respiratory tract infection incidence and localised meningitis epidemics: an analysis of high-resolution surveillance data fr…
2017
AbstractMeningococcal meningitis epidemics in the African meningitis belt consist of localised meningitis epidemics (LME) that reach attack proportions of 1% within a few weeks. A meningococcal serogroup A conjugate vaccine was introduced in meningitis belt countries from 2010 on, but LME due to other serogroups continue to occur. The mechanisms underlying LME are poorly understood, but an association with respiratory pathogens has been hypothesised. We analysed national routine surveillance data in high spatial resolution (health centre level) from 13 districts in Burkina Faso, 2004–2014. We defined LME as a weekly incidence rate of suspected meningitis ≥75 per 100,000 during ≥2 weeks; and…
Distribution of maternity units and spatial access to specialised care for women delivering before 32 weeks of gestation in Europe
2010
Contains fulltext : 88841.pdf (Publisher’s version ) (Closed access) Survival and quality of life are improved for very preterm babies when delivery occurs in a maternity unit with on-site neonatal intensive care (level III unit). We investigated the impact of distance on the probability of delivering in such a unit for births before 32 weeks of gestation from 9 European regions with diverse perinatal health systems (the MOSAIC cohort). We analysed distances between women's homes, and the nearest level III in population quartiles, adjusting for maternal and pregnancy characteristics. Living farther away from a level III reduced access to specialised care everywhere; in some regions women re…
Une relation trophique originale : la vection entomophile d'agents pathogènes
2013
Bgpi : équipe 6 chapitre 34; Une relation trophique originale : la vection entomophile d'agents pathogènes
Santé et développement durable : proposition d'une grille de lecture de la contribution des politiques de santé au développement durable
2002
Development economics and health economics evolved according to dynamics which their are appropriate.The issues concerning the role of health in developing countries, if they had formerly no echo which theytake on today, nevertheless concerned a rather big number of specialists. The approaches in terms of humancapital, endogenous growth... tend today to recognise health and education as pillars of human development.But the objective of development, qualified since the Bruntland's report, of "sustainable", does it give way tothe development of health systems? The aim of this paper is double: on one hand, it consists in tempting aclarification of the concept of sustainable development general…
MAVIE-Lab Sports: a mHealth for Injury Prevention and Risk Management in Sport
2018
International audience; Smart-phones technology and the development of mHealth (Mobile Health) applications offer an opportunity to design intervention tools to influence health behavior changes. The MAVIE-Lab is a mHealth application including a DSS (Desicion Support System) to assist in the personalized evaluation of HLIs (Home, Leisure and Sport Injuries) risk and to promote the adoption of prevention measures. MAVIE-Lab Sports will be the first module of the mobile application. The purpose of this PhD project is to improve a particular module of MAVIE-Lab, devoted to sports (MAVIE-Lab Sports), in different aspects: statistical modeling, design and ergonomics. It also aims to evaluate sy…
Singuliers généralistes. Sociologie de la médecine générale.
2010
International audience; Chacun de nous connaît un médecin généraliste, en qui il peut trouver un interlocuteur privilégié pour ses soucis de santé. En tant que groupe professionnel pourtant, les généralistes ont longtemps été peu considérés dans notre système de soins et restent méconnus : que sait-on des façons d'être généraliste ? de l'évolution de la profession ? Souvent passionnés par leur métier vécu comme un engagement personnel, les médecins généralistes sont-ils satisfaits de leurs conditions de travail et de leur place dans la société? À partir d'enquêtes récentes, des sociologues expliquent ce que sont et font les généralistes dans leur cabinet, ils analysent les "flous du métier"…
A Randomised Controlled Trial to Test the Effectiveness of Planning Strategies to Improve Medication Adherence in Patients with Cardiovascular Disease
2017
Background Low levels of adherence to medication prescribed to treat and manage chronic disease may lead to maladaptive health outcomes. Theory-based, easy-to-administer interventions that promote patients’ effective self-regulation of their medication-taking behaviour are needed if adherence is to be maximised. We tested the effectiveness of an intervention adopting planning techniques to promote medication adherence. Methods Outpatients with cardiovascular disease (N = 71) were allocated to either an experimental condition, in which participants were asked to form implementation intentions and coping plans related to their treatment, or to a no-planning control condition, in which partici…
Evaluation of the impact of therapeutic management on the survival and quality of life of patients with follicular lymphoma or diffuse large B cell l…
2014
In France, hematologic malignancies, which are the sixthmost common cancers, are amajor public healthproblem. This work aimed to study the impact of the therapeutic management on survival and healt-relatedquality of life (HRQoL) in patients with these hematologic malignancies. The first objective of this work is topresent an overview of the epidemiology of lymphoid malignancies with a study of changes in the incidenceand net survival in the Côte d’Or department between 1980 and 2009. The incidence, which has increased since1980, seems to have stabilized since the 2000s for some entities, including follicular lymphoma (FL) and diffuselarge B-cell lymphoma (DLBCL). Overall, we observed an imp…
A Comparative Analysis of Hospital Readmissions in France and the US
2015
International audience; Policymakers in the US and France are struggling to improve coordination among hospitals and other health care providers. A comparison of hospital readmission rates, and the factors that may explain them, can provide important insights about the French and US health care systems. In addition, it illustrates a methodological approach to comparative research: how an empirical inquiry along a single indicator can reveal broader issues about system-wide differences across health care systems and policy. Using data from three French regions, the article extends a previous national-level comparison indicating that rates of hospital readmission for the population aged 65+ a…