Search results for "(BMP)"
showing 3 items of 23 documents
Signaling through BMPR-IA regulates quiescence and long-term activity of neural stem cells in the adult hippocampus.
2010
SummaryNeural stem cells (NSCs) in the adult hippocampus divide infrequently, and the molecules that modulate their quiescence are largely unknown. Here, we show that bone morphogenetic protein (BMP) signaling is active in hippocampal NSCs, downstream of BMPR-IA. BMPs reversibly diminish proliferation of cultured NSCs while maintaining their undifferentiated state. In vivo, acute blockade of BMP signaling in the hippocampus by intracerebral infusion of Noggin first recruits quiescent NSCs into the cycle and increases neurogenesis; subsequently, it leads to decreased stem cell division and depletion of precursors and newborn neurons. Consistently, selective ablation of Bmpr1a in hippocampal …
Efficienza idrologico-idraulica di pavimentazioni semi-permeabili per il controllo degli allagamenti pluviali
2021
La sostenibilità del binomio “acqua – città” è uno spunto interessante di discussione e confronto nell’ambito delle diverse discipline che affrontano il tema dell’ambiente urbano, delle sue continue trasformazioni, e della necessità di resilienza agli allagamenti. Le soluzioni tecniche e tecnologiche oggi a disposizione di chi si occupa di queste problematiche, per affrontare il tema di un rapporto sostenibile tra l’acqua e l’ambiente urbano sono molteplici, alcune tradizionali e di consolidata esperienza, altre innovative e di più recente applicazione sul campo. L’urbanizzazione influisce negativamente sulla formazione e propagazione dei deflussi; nelle aree urbanizzate i rapidi processi d…
Stormwater Source Control as a Strategy for Sustainable Development: State of the Practice and Perceived Trends
2005
The primary objective of the paper is to draw upon the experiences acquired in many parts of the world to provide an up-to-date summary of the state of the practice for source control techniques and approaches, in a sustainable development context. After a discussion of the prevailing context for urban drainage approaches, three main themes covering techniques and design criteria, institutional aspects and performance issues are discussed relative to source control implementation. The discussion is based on findings from the compilation and analysis of available literature, recently developed databases, the experience of the different members of the SOCOMA group and recent research on desig…