Search results for "-n"

Analysis of the impact of sex and age on the variation in the prevalence of antinuclear autoantibodies in Polish population: a nationwide observation…

2022

AbstractThe detection of antinuclear autoantibody (ANA) is dependent on many factors and varies between the populations. The aim of the study was first to assess the prevalence of ANA in the Polish adult population depending on age, sex and the cutoff threshold used for the results obtained. Second, we estimated the occurrence of individual types of ANA-staining patterns. We tested 1731 patient samples using commercially available IIFA using two cutoff thresholds of 1:100 and 1:160. We found ANA in 260 participants (15.0%), but the percentage of positive results strongly depended on the cutoff level. For a cutoff threshold 1:100, the positive population was 19.5% and for the 1:160 cutoff th…

Interleukin 10 polymorphisms in ankylosing spondylitis.

2003

Genetic polymorphisms of the IL10 promoter region have been implicated in many autoimmune diseases, including seronegative spondyloarthropathies. We studied three SNPs (IL10-1087, -824, and -597) and two microsatellites (IL10R and IL10G) lying within the promoter region of IL10 for association with susceptibility to and clinical manifestations of ankylosing spondylitis (AS), a common form of spondyloarthritis. Four hundred and sixty-eight individuals from 182 Finnish families affected with AS were studied. No association between individual IL10 promoter region polymorphisms or marker haplotype was observed with susceptibility to AS, but weak association was noted between the IL10-597 and -8…

Presence of Serum Antinuclear Antibodies Does Not Impact Long-Term Outcomes in Nonalcoholic Fatty Liver Disease

2020

Introduction We investigated the longitudinal impact of antinuclear antibody (ANA) on clinical outcomes and survival in nonalcoholic fatty liver disease (NAFLD). Methods ANA were found in 16.9% of 923 biopsy-proven NAFLD patients, but none of them had histologic autoimmune hepatitis (AIH) or developed AIH after a mean follow-up of 106±50 months. Results Although ANA-positive cases had a higher prevalence of nonalcoholic steatohepatitis at baseline, the occurrence of liver-related events, hepatocellula carcinoma, cardiovascular events, extrahepatic malignancy, and overall survival were similar to ANA-negative. Discussion Once AIH has been ruled out, the long-term outcomes and survival are un…

MUSCLE BIOENERGETIC ABNORMALITY IN MYOTONIC-DYSTROPHY - A SECONDARY MITOCHONDRIAL DISORDER

1993

International audience; Abstract: The thenar muscles and gastrocnemius of a patient with myotonic dystrophy were investigated, at rest, by phosphorus nuclear magnetic resonance spectroscopy. A decrease in phosphocreatine level and an increase in inorganic phosphate and phosphodiester levels were found in the gastrocnemius, which was clinically spared, whilst the thenar muscles, which were wasted and affected by myotonia, exhibited only an increased inorganic phosphate level and an elevated pH. These findings were comparable with those found in other muscular disorders, such as Duchenne's and Becker's dystrophies, as well as in limb girdle dystrophy. They suggested that the abnormalities obs…

I musei naturalistici come presidi ambientali e culturali. L'Orto botanico di Palermo

2013

La funzione degli Orti botanici, fondamentalmente, si esplica nella conservazione, nella ricerca scientifica, nelle attività espositive ed educative. I punti di forza dell’azione sociale di questi tipi di musei deriva sia dalla capacità di produrre e diffondere la conoscenza scientifica, sia dalla ricchezza patrimoniale posseduta. Una serie di emergenze planetarie e le prospettive incerte per l’ambiente, le società, le economie di tutte le nazioni del mondo configurano lo scenario d’oggi. Questa situazione richiede la costruzione collettiva di nuove forme di sentire, pensare e agire nella ricerca di soluzione ai problemi contemporanei. Si tratta quindi, per i musei scientifici, di intrapren…

Persistence in memory of configural odor mixture and components in the newborn rabbit

2014

Persistence in memory of configural odor mixture and components in the newborn rabbit. 36. annual meeting - association for chemoreception sciences (AChemS XXXVI)

HHT-alpha and predictor-corrector scheme for dynamic contact problem by Nitsche's method

2022

Dans ce travail nous sommes intéressés par le problème de contact unilatéral en dynamique et sans frottement. Nous nous concentrons sur l'évolution en temps de l'impact d'un corps élastique linéaire sur un obstacle rigide, et avons souhaité en particulier étudier comment combiner des schémas en temps comme HHT et prédicteur-correcteur avec un traitement du contact via Nitsche, ce qui n'a jamais été effectué auparavant. Nous présenterons aussi quelques résultats numériques en faisant attention au comportement numérique : stabilité du schéma, conservation ou non de l'énergie et oscillations parasites. Mots clés-problème de contact, méthode de Nitsche, éléments finis, dynamique.

A greasy-skinned worker: gender, class and work in the 20th-century life story of a female labourer

2013

Thinking Narratively. Between Novel-Essay and Narrative Essay

2022

What is the connection between philosophical enquiries and storytelling in contemporary narrative? Is it possible to outline some features of a so-called philosophical fiction in Western literature throughout the last two centuries? This book aims to provide a plural answer, hosting extensive essays by seven young researchers coming from different fields (Theory of literature, German, American, Russian and Italian contemporary literature, history and evolution of the essayistic form). A short The volume is addressed to all those with a strong interest in both evolution of philosophical speech and history of the novel and has a strong vocation to promote interdisciplinarity in literary studi…

Content Domain and Language Competence in Computer-mediated Conversation for Learning

2012

This study addresses the issue of interactional dominance in Teletandem conversations, in which two speakers communicate via video calls and chat and alternatively use their L2, the latter being the native language of the interlocutor. In particular, the research focuses on the impact of language competence (native/non-native) and content expertise (minus/plus familiarity with the topic at hand) on the role assumed by each interlocutor in structuring conversation. The data consists of 3 hours of computer-mediated recorded and transcribed conversations during 3 meetings: meeting 1 comprises free discussion for mutual introduction; meeting 2 is a discussion in English of a topic chosen by the…