Search results for "030227 psychiatry"
showing 10 items of 1017 documents
Impaired Right Temporoparietal Junction–Hippocampus Connectivity in Schizophrenia and Its Relevance for Generating Representations of Other Minds
2018
Schizophrenia is associated with impaired and exaggerated Theory of Mind processes, pointing on alterations in generating a representation of another person's mind. Despite recent work on healthy subjects suggesting that a coupling between the right temporoparietal junction (rTPJ) and the hippocampus is relevant for building representations of others' intentions, the neural basis of related dysfunctions in patients with schizophrenia remains unclear. Therefore, we used structural and functional magnetic resonance imaging together with a modified prisoner's dilemma game to test the hypotheses, that patients show dysfunctional social updating on behavioral level accompanied by altered rTPJ-hi…
Suicide attempts in chronically depressed individuals: What are the risk factors?
2020
Abstract Chronically depressed individuals have a high suicide risk. However, it is an open question whether previously observed risk factors for suicide attempts also apply to chronic depression or whether there are specific risk factors related to chronic-recurrent illness. We drew from a large group of chronically depressed individuals seeking psychotherapy to investigate demographic and psychological factors related to previous suicide attempts. Participants took part in the SCID and filled out established questionnaires. Among 368 chronically depressed individuals (68.7% women; Mage = 40.95 years), 75 participants (19.4%) reported previous suicide attempts. Men were more likely to have…
The Prevalence and Consequences of Adverse Childhood Experiences in the German Population
2019
Background Multiple studies have shown a link between cumulative adverse experiences in childhood and a wide variety of psychosocial problems in later life. There have not been any pertinent representative studies of the German population until now. The goal of this study is to determine the frequency of adverse childhood experiences (ACE), the extent to which they manifest themselves in patterns of co-occurrence, and their possible connection to psychosocial abnormalities in the German population. Methods 2531 persons (55.4% female) aged 14 years and up (mean [M] = 48.6 years, standard deviation [SD] = 18) were retro- spectively studied for ACE and psychosocial abnormalities by means of th…
Spanish Adaptation and Validation of the Short Internalized Homonegativity Scale (SIHS)
2016
Internalized homophobia has been related to mental health problems and sexual risk behaviors among nonheterosexual people. This article validates the Spanish adaptation of the Short Internalized Homonegativity Scale (SIHS). For this purpose, 347 men and 183 women completed the instrument. Exploratory factorial analysis showed three factors: public identification as homosexual (PIH), sexual comfort with homosexual people (SEXC), and social comfort with homosexual people (SOCC). These factors explained 57.96% of total variance. In addition, confirmatory factorial analysis supported this structure and internal consistency (Cronbach's alpha) was.80 for the full scale. The three subscales ranged…
Burnout Clinical Subtypes Questionnaire (BCSQ-36): reliability and validity study in Latvia
2020
The study aimed to test the validity of the burnout subtypes hierarchic model operationalized by the 'Burnout Clinical Subtypes Questionnaire' (BCSQ-36) and its applicability in other cultures. To that aim psychometric properties, factorial and convergent validity regarding the Maslach Burnout Inventory - General Survey (MBI-GS), and correlation with demographic factors were reviewed. A voluntary internet-based approach was used on a multi-occupational sample of adult Latvians (n = 394). The results of the internal consistency of the Latvian version of the BCSQ-36 exceeded .89 for all three subtypes. The CFA was used to test a hierarchical factorial model, and the analysis revealed an accep…
Design and validation of a brief scale for cognitive evaluation in people with a diagnosis of schizophrenia (BCog‐S)
2019
WHAT IS KNOWN ON THE SUBJECT?: Schizophrenia is often related to cognitive deficits. Mental health nurses are involved in health promotion, prevention, treatment and rehabilitation in schizophrenia. However, the nursing literature addressing cognitive rehabilitation from schizophrenia is very limited. Cognition and its domains (communication, information processing, attentiveness, concentration, orientation, memory and calculation skills) are established by the Nursing Outcomes Classification (NOC), but they are difficult to measure. WHAT THE PAPER ADDS TO EXISTING KNOWLEDGE?: We present a new standardized cognitive assessment to be administered by nurses to people diagnosed with schizophre…
Occurrence and clinical characteristics of Compulsive Sexual Behavior Disorder (CSBD): A cluster analysis in two independent community samples.
2020
AbstractBackground and aimsCompulsive Sexual Behavior Disorder (CSBD) is characterized by a persistent failure to control intense and recurrent sexual impulses, urges, and/or thoughts, resulting in repetitive sexual behavior that causes a marked impairment in important areas of functioning. Despite its recent inclusion in the forthcoming ICD-11, concerns regarding its assessment, diagnosis, prevalence or clinical characteristics remain. The purpose of this study was to identify participants displaying CSBD through a novel data-driven approach in two independent samples and outline their sociodemographic, sexual, and clinical profile.MethodsSample 1 included 1,581 university students (female…
The association between different domains of quality of life and symptoms in primary care patients with emotional disorders
2018
AbstractDespite the importance of quality of life (QoL) in primary care patients with emotional disorders, the specific influence of the symptoms of these disorders and the sociodemographic characteristics of patients on the various QoL domains has received scant attention. The aim of the present study of primary care patients with emotional disorders was to analyse the associations between four different QoL domains and the most prevalent clinical symptoms (i.e., depression, anxiety and somatization), while controlling for sociodemographic variables. A total of 1241 participants from 28 primary care centres in Spain were assessed with the following instruments: the Patient Health Questionn…
Cognitive and emotional empathy in patients with schizophrenia spectrum disorders: A replication and extension study.
2019
Impairments of social cognition are defined as core features in the pathology of schizophrenia. In a study by Lehmann and colleagues (2014), patients with schizophrenia have been shown to demonstrate a diminished capacity to understand others' emotions (i.e. cognitive empathy), but a preserved ability to share or feel the emotional states of others (i.e. emotional empathy). Here, we report on an independent replication study investigating cognitive and emotional empathy in 35 patients with schizophrenia spectrum disorders and a matched control group, which 1) confirms that patients demonstrate preserved emotional empathy in self-report and behavioural measurements, and 2) reveals associatio…
Body mass index as a determinant of clozapine plasma concentrations: A pharmacokinetic-based hypothesis
2021
Background: Knowledge regarding the impact of body composition measures on pharmacokinetics of antipsychotics is limited. Aims: Our aim was to investigate the impact of body weight and body mass index on clozapine pharmacokinetics using a therapeutic drug monitoring database. Methods: A large therapeutic drug monitoring dataset of clozapine plasma concentrations considering three patient subgroups was analysed: a control group (CLZ0, 20–30 kg/m2, n=266), a group with high body mass index (CLZhigh, body mass index ⩾30 kg/m2, n=162) and with low body mass index values (CLZlow, body mass index <20 kg/m2, n=27). Comparisons of plasma and dose-adjusted plasma concentrations (C/D) of clozapine…