Search results for "09"

A novel device for assessing the health risk caused by hand-arm vibrations in olives harvesting

2012

The mechanization of olive harvesting is very important both to reduce the costs of production and to assure the oil quality because the manual harvest does not allow to operate at the right time and also need a long period to be completed. The use of portable shakers, that are spreading more than others typologies, can give a solution to the problem. However, the use of such equipment may involve risk of exposure to hand-transmitted vibration. The aim of this study was to assess the level of exposure to hand-arm vibration of the operators using portable shakers (reference standards UNI EN ISO 5349-1:2004, Italian Low Decree 81/2008). The research presented here concerns the definition of a…

Safety of Tyrosine Kinase Inhibitors in Patients With Differentiated Thyroid Cancer: Real-World Use of Lenvatinib and Sorafenib in Korea

2019

Background: Thyroid cancer has become the most common cancer in Korea. Generally, thyroid cancer patients have a good prognosis; however, 15–20% of patients experience recurrence or distant metastasis or are refractory to standard treatment. We assessed the safety of sorafenib and lenvatinib in patients with advanced or metastatic radioactive iodine-refractory differentiated thyroid cancers (DTC) consecutively treated at a tertiary center in South Korea.Methods: We retrospectively reviewed the charts of all consecutive patients with DTC treated during ≥6 months with lenvatinib (February 2016–April 2018) and sorafenib (January 2014–April 2018) at Gangnam Severance Hospital. Patients were tre…

Efficacy of Long-Term Treatment of Autosomal Recessive Hypercholesterolemia With Lomitapide: A Subanalysis of the Pan-European Lomitapide Study

2022

Backgroundand aim: Autosomal recessive hypercholesterolemia (ARH) is a rare autosomal recessive disorder of low-density lipoprotein (LDL) metabolism caused by pathogenic variants in the LDLRAP1 gene. Like homozygous familial hypercholesterolemia, ARH is resistant to conventional LDL-lowering medications and causes a high risk of atherosclerotic cardiovascular diseases (ASCVDs) and aortic valve stenosis. Lomitapide is emerging as an efficacious therapy in classical HoFH, but few data are available for ARH.Results: This is a subanalysis carried out on nine ARH patients included in the Pan-European Lomitapide Study. The age at starting lomitapide was 46 (interquartile range (IQR), 39.0–65.5) y…

Brief an Johann Gottfried Herder

1797

A methodological look at the controversy about the influence of salt intake on cardiovascular risk

2012

Cardiovascular diseases are a major cause of premature death and disability. They represent an extraordinarily strong financial burden upon health-care systems in ‘‘developed’’ countries. Elevated blood pressure is a major cause of cardiovascular disease. There is much evidence that cardiovascular risk increases from normal blood pressure (i.e., from 115/75 mmHg upwards) [1]. Overwhelming evidence shows that reducing salt intake from 9–12 g/day to 5–6 g/day lowers blood pressure [2]. Blood pressure is a surrogate endpoint, but may be related to a reduction of morbidity and mortality due to cardiovascular causes. Thus, intensive support and encouragement to cut down on the intake of salt in …

Further development of integrated threat theory and intergroup contact: a reply to Aberson (2015)

2016

ABSTRACTThis essay furthers a dialogue about the theoretical and statistical merits of Croucher's [(2013). Integrated threat theory and acceptance of immigrant assimilation: An analysis of Muslim immigration in Western Europe. Communication Monographs, 80, 46–62] study exploring the relationships between threat from an immigrant group, belief that an immigrant wants to assimilate, and intergroup contact. Key points of divergence include assertions that (a) the relationships in the original piece are counter to previous literature/relationships, (b) the correlations presented are implausible, (c) the magnitude of the relationships is too strong, and (d) the manuscript has “odd” multiple regr…

La sanità fra espansione dell'impiego, deficit e sviluppo

2012

Si analizza l'anomala dimensione del mercato del lavoro siciliano nel settore della sanità, e le sue conseguenze sull'accumulo del deficit strutturale degli anni duemila.

La sanità alla prova nelle regioni del Sud

2012

Si valuta l'esperienza dei Piani di contenimento e riqualificazione della spesa sanitaria regionale nelle regioni meridionali. Dopo una fase di decentramento senza autonomia in cui le regioni avevano accumulato deficit strutturali, il nuovo regime di controllo e monitoraggio da parte del centro ha determinato una positiva risposta delle regioni coinvolte.

Una trona sense tron. Predicació i interferència política en el barroc valencià

2014

Resum: La predicació valenciana durant el barroc presenta algunes diferències substantives amb la castellana, com ara l’absència d’un to tenebrista i condemnatori. Una altra divergència és que la ingerència política en la predicació no solament és menor, sinó que la proverbial legitimació de la monarquia adquireix entre els predicadors valencians uns matisos que la singularitzen, perquè l’enfocament «legitimador» s’adreça més als orígens del Regne —i, doncs, a Jaume I, pràcticament sacralitzat— que no a la lloança dels Habsburg, només aplaudits per la seua condició de catòlics, enemics del protestantisme. D’una manera indirecta, però persistent, s’hi albiren notes que poden avalar —bé que a…

Nonlinear Absorption and Refraction of Picosecond and Femtosecond Pulses in HgTe Quantum Dot Films

2021

We report measurements of the saturated intensities, saturable absorption, and nonlinear refraction in 70-nm thick films containing 4 nm HgTe quantum dots. We demonstrate strong nonlinear refraction and saturable absorption in the thin films using tunable picosecond and femtosecond pulses. Studies were carried out using tunable laser pulses in the range of 400–1100 nm. A significant variation of the nonlinear refraction along this spectral range was demonstrated. The maximal values of the nonlinear absorption coefficients and nonlinear refractive indices determined within the studied wavelength range were −2.4 × 10−5 cm2 W−1 (in the case of 28 ps, 700 nm probe pulses) and −3 × 10−9 cm2 W−1 …